add selectedMOIs to saved search

ui/pages/Search/components/filters/LocusListSelector.jsx

@@ -33,26 +33,28 @@ class BaseLocusListDropdown extends React.Component {
     locusListOptions: PropTypes.arrayOf(PropTypes.object),
     loading: PropTypes.bool,
     onChange: PropTypes.func,
+    selectedMOIs: PropTypes.arrayOf(PropTypes.string),
   }
 
   shouldComponentUpdate(nextProps) {
-    const { locusList, locusListOptions, onChange, loading } = this.props
+    const { locusList, locusListOptions, onChange, loading, selectedMOIs } = this.props
     return nextProps.locusListOptions !== locusListOptions ||
       nextProps.onChange !== onChange ||
       nextProps.loading !== loading ||
       nextProps.locusList.locusListGuid !== locusList.locusListGuid ||
-      (!!locusList.locusListGuid && nextProps.locusList.rawItems !== locusList.rawItems)
+      (!!locusList.locusListGuid && nextProps.locusList.rawItems !== locusList.rawItems) ||
+      nextProps.selectedMOIs !== selectedMOIs
   }
 
   componentDidUpdate(prevProps) {
-    const { locusList, onChange } = this.props
+    const { locusList, onChange, selectedMOIs } = this.props
 
     if (prevProps.locusList.rawItems !== locusList.rawItems) {
       const { locusListGuid } = locusList
 
       if (locusList.paLocusList) {
-        const panelAppItems = formatPanelAppItems(locusList.items)
-        onChange({ locusListGuid, panelAppItems })
+        const panelAppItems = formatPanelAppItems(locusList.items, selectedMOIs)
+        onChange({ locusListGuid, panelAppItems, selectedMOIs })
       } else {
         const { rawItems } = locusList
         onChange({ locusListGuid, rawItems })
@@ -96,7 +98,7 @@ const SUBSCRIPTION = { values: true }
 const LocusListSelector = React.memo(({ value, ...props }) => (
   <LocusListsLoader allProjectLists hideLoading>
     <LocusListItemsLoader locusListGuid={value.locusListGuid} reloadOnIdUpdate content hideLoading>
-      <LocusListDropdown {...props} />
+      <LocusListDropdown selectedMOIs={value?.selectedMOIs} {...props} />
     </LocusListItemsLoader>
   </LocusListsLoader>
 ))

ui/shared/components/panel/search/PaLocusListSelector.jsx

@@ -0,0 +1,50 @@
+import React from 'react'
+import { BaseSemanticInput } from 'shared/components/form/Inputs'
+import { connect } from 'react-redux'
+import { getLocusListsWithGenes } from 'redux/selectors'
+import { formatPanelAppItems } from 'shared/utils/panelAppUtils'
+import PropTypes from 'prop-types'
+
+const EMPTY_STRING = ''
+
+class PaLocusListSelector extends React.Component {
+
+  static propTypes = {
+    locus: PropTypes.object,
+    locusList: PropTypes.object,
+    onChange: PropTypes.func,
+    value: PropTypes.string,
+    color: PropTypes.string,
+  }
+
+  shouldComponentUpdate(nextProps) {
+    const { locus, value } = this.props
+    return nextProps.locus.selectedMOIs !== locus.selectedMOIs ||
+      nextProps.value !== value
+  }
+
+  componentDidUpdate(prevProps) {
+    const { locus, locusList, onChange, color } = this.props
+    const { selectedMOIs } = locus
+
+    if (prevProps.locus.selectedMOIs !== selectedMOIs) {
+      const panelAppItems = formatPanelAppItems(locusList?.items, selectedMOIs)
+      if (panelAppItems[color]) {
+        onChange(panelAppItems[color])
+      } else {
+        onChange(EMPTY_STRING)
+      }
+    }
+  }
+
+  render() {
+    return <BaseSemanticInput {...this.props} />
+  }
+
+}
+
+const mapStateToProps = (state, ownProps) => ({
+  locusList: getLocusListsWithGenes(state)[ownProps.locus.locusListGuid],
+})
+
+export default connect(mapStateToProps)(PaLocusListSelector)

ui/shared/components/panel/search/PaMoiSelector.jsx

@@ -4,7 +4,7 @@ import { connect } from 'react-redux'
 
 import { getLocusListsWithGenes } from 'redux/selectors'
 import { Multiselect } from 'shared/components/form/Inputs'
-import { moiToMoiInitials, formatPanelAppItems } from 'shared/utils/panelAppUtils'
+import { moiToMoiInitials } from 'shared/utils/panelAppUtils'
 import { PANEL_APP_MOI_OPTIONS } from 'shared/utils/constants'
 
 const EMPTY_LIST = []
@@ -13,24 +13,6 @@ class PaMoiDropdown extends React.PureComponent {
 
   static propTypes = {
     locusList: PropTypes.object,
-    onChange: PropTypes.func,
-  }
-
-  handleMOIselect = (selectedMOIs) => {
-    const { locusList, onChange } = this.props
-
-    const panelAppItems = formatPanelAppItems(
-      locusList.items?.filter((item) => {
-        let result = true
-        const initials = moiToMoiInitials(item.pagene?.modeOfInheritance, false)
-        if (selectedMOIs && selectedMOIs.length !== 0) {
-          result = selectedMOIs.some(moi => initials.includes(moi))
-        }
-        return result
-      }),
-    )
-
-    onChange({ ...panelAppItems })
   }
 
   moiOptions = () => {
@@ -50,15 +32,15 @@ class PaMoiDropdown extends React.PureComponent {
   }
 
   render() {
-    const { selectedMOIs, label, width, locusList } = this.props || []
+    const { value, label, width, locusList, onChange } = this.props || []
     const disabled = !locusList?.items
     return (
       <Multiselect
         label={label}
-        value={selectedMOIs}
+        value={value}
         width={width}
         inline
-        onChange={this.handleMOIselect}
+        onChange={onChange}
         placeholder="Showing all MOIs as listed in Panel App"
         disabled={disabled}
         options={disabled ? EMPTY_LIST : this.moiOptions()}

ui/shared/components/panel/search/constants.js

@@ -30,6 +30,7 @@ import {
 
 import LocusListItemsFilter from './LocusListItemsFilter'
 import PaMoiSelector from './PaMoiSelector'
+import PaLocusListSelector from './PaLocusListSelector'
 
 export const getSelectedAnalysisGroups = (
   analysisGroupsByGuid, familyGuids,
@@ -464,6 +465,7 @@ export const FREQUENCIES = [...SNP_FREQUENCIES, ...MITO_FREQUENCIES, ...SV_FREQU
 
 export const LOCUS_FIELD_NAME = 'locus'
 export const PANEL_APP_FIELD_NAME = 'panelAppItems'
+export const SELECTED_MOIS_FIELD_NAME = 'selectedMOIs'
 const VARIANT_FIELD_NAME = 'rawVariantItems'
 const PANEL_APP_COLORS = [...new Set(
   Object.entries(PANEL_APP_CONFIDENCE_LEVELS).sort((a, b) => b[0] - a[0]).map(config => config[1]),
@@ -485,9 +487,11 @@ export const LOCATION_FIELDS = [
     label: color === 'none' ? 'Genes' : `${camelcaseToTitlecase(color)} Genes`,
     labelHelp: 'A list of genes, can be separated by commas or whitespace',
     component: LocusListItemsFilter,
+    filterComponent: PaLocusListSelector,
     width: 3,
     shouldShow: locus => !!locus[PANEL_APP_FIELD_NAME],
     shouldDisable: locus => !!locus[VARIANT_FIELD_NAME],
+    color,
   })),
   {
     name: VARIANT_FIELD_NAME,
@@ -498,7 +502,7 @@ export const LOCATION_FIELDS = [
     shouldDisable: locus => !!locus[LOCUS_LIST_ITEMS_FIELD.name] || !!locus[PANEL_APP_FIELD_NAME],
   },
   {
-    name: PANEL_APP_FIELD_NAME,
+    name: SELECTED_MOIS_FIELD_NAME,
     label: 'Modes of Inheritance',
     labelHelp: 'Filter the Gene List based on Modes of Inheritance from Panel App',
     component: LocusListItemsFilter,

ui/shared/utils/panelAppUtils.ts

@@ -64,6 +64,7 @@ export const panelAppUrl = (
 
 export type PanelAppItem = {
   pagene?: {
+    modeOfInheritance?: string;
     confidenceLevel?: 0 | 1 | 2 | 3 | 4
   }
   display: string
@@ -74,15 +75,30 @@ export type PanelAppItem = {
  * and concatenated item displays as values.
  *
  * @param {PanelAppItem[] | null | undefined} items - The array of PanelApp items to format.
+ * @param {string[] | null | undefined} selectedMOIs - Optional array of selected MOIs for filtering.
  * @returns {Record<string, string> | never[]} A record where keys represent confidence levels and values
  * are concatenated item displays, or an empty array if `items` is falsy.
  */
-export const formatPanelAppItems = (items: PanelAppItem[] | null | undefined): Record<string, string> | never[] => {
+export const formatPanelAppItems = (
+  items: PanelAppItem[] | null | undefined,
+  selectedMOIs?: string[] | null
+): Record<string, string> | never[] => {
   if (!items) {
     return []
   }
 
+  const hasSelectedMoi = (item: { pagene?: any; display?: string }, selectedMOIs: any[]) => {
+    if (!selectedMOIs || selectedMOIs.length === 0) {
+      return true
+    }
+    const initials = moiToMoiInitials(item.pagene?.modeOfInheritance, false)
+    return selectedMOIs.some((moi) => initials.includes(moi))
+  }
+
   return items.reduce((acc, item) => {
+    if (!hasSelectedMoi(item, selectedMOIs)) {
+      return acc
+    }
     const color: string = PANEL_APP_CONFIDENCE_LEVELS[item.pagene?.confidenceLevel] || PANEL_APP_CONFIDENCE_LEVELS[0]
     return { ...acc, [color]: [acc[color], item.display].filter(val => val).join(', ') }
   }, {} as Record<string, string>)