wes/wgs: stricter comp het inheritance filtering #4528
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jklugherz
commented
Dec 10, 2024
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| This folder comprises a Hail (www.hail.is) native Table or MatrixTable. | |||
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updated variant 4 here to be hom-alt for an unaffected family member (would this be a valid call in real life?) to illustrate how comp het search would behave if one sample type is invalid
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yes this is possible although not super common. But, for example, sometimes if a person has a variant on one strand and a deletion on the other the caller calls it as hom alt, so like this could happen if a parent has an alt and a deletion and the child inherits the deletion and not the alt allele. Its a weird edge case but okay to include in a test
jklugherz
changed the title
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