From d238606bfc39c9489ba2ca78a593336358983d85 Mon Sep 17 00:00:00 2001 From: Sebastian Duesing <66700705+sebastianduesing@users.noreply.github.com> Date: Mon, 18 Nov 2024 16:00:36 -0600 Subject: [PATCH 01/12] Import versioned OMO --- src/ontology/obi-edit.owl | 2 +- 1 file changed, 1 insertion(+), 1 deletion(-) diff --git a/src/ontology/obi-edit.owl b/src/ontology/obi-edit.owl index 8d7cd215..2f30f8bf 100644 --- a/src/ontology/obi-edit.owl +++ b/src/ontology/obi-edit.owl @@ -14,7 +14,7 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - + From d7679f1d40d3eb4b84efc276d3d79074d89054e2 Mon Sep 17 00:00:00 2001 From: Sebastian Duesing <66700705+sebastianduesing@users.noreply.github.com> Date: Fri, 22 Nov 2024 12:52:31 -0600 Subject: [PATCH 02/12] Update to devices.owl --- src/ontology/modules/devices.owl | 6 +++--- 1 file changed, 3 insertions(+), 3 deletions(-) diff --git a/src/ontology/modules/devices.owl b/src/ontology/modules/devices.owl index 03d99d54..2052b972 100644 --- a/src/ontology/modules/devices.owl +++ b/src/ontology/modules/devices.owl @@ -9247,7 +9247,7 @@ PERSON: Mark Andrew Miller https://github.com/obi-ontology/obi/issues/1825 Alicia Clum - Illumina HiSeq Series Instrument + Illumina HiSeq series instrument @@ -9271,7 +9271,7 @@ PERSON: Mark Andrew Miller https://github.com/obi-ontology/obi/issues/1825 Alicia Clum - Illumina NextSeq Series Instrument + Illumina NextSeq series instrument @@ -9294,7 +9294,7 @@ PERSON: Mark Andrew Miller https://github.com/obi-ontology/obi/issues/1825 Alicia Clum - Illumina NovaSeq Series Instrument + Illumina NovaSeq series instrument From a0e030f80ab02ca079ed56f890ee2967659957f5 Mon Sep 17 00:00:00 2001 From: Sebastian Duesing <66700705+sebastianduesing@users.noreply.github.com> Date: Fri, 22 Nov 2024 12:53:39 -0600 Subject: [PATCH 03/12] Relabel specified input/output terms to remove underscores --- src/ontology/obi-edit.owl | 20 ++++---- src/ontology/templates/administration.tsv | 2 +- .../templates/antibody-purification.tsv | 2 +- src/ontology/templates/assays.tsv | 6 +-- src/ontology/templates/biopsy.tsv | 2 +- src/ontology/templates/data-sets.tsv | 2 +- .../templates/data-transformations.tsv | 8 +-- src/ontology/templates/devices.tsv | 2 +- src/ontology/templates/epitope-assays.tsv | 2 +- .../templates/physical-examination.tsv | 2 +- src/ontology/templates/sample-collection.tsv | 2 +- src/ontology/templates/sequence-analysis.tsv | 2 +- .../templates/specimen-assay-data.tsv | 50 +++++++++---------- src/ontology/templates/specimens.tsv | 28 +++++------ src/ontology/templates/study-designs.tsv | 2 +- 15 files changed, 66 insertions(+), 66 deletions(-) diff --git a/src/ontology/obi-edit.owl b/src/ontology/obi-edit.owl index 2f30f8bf..a9a30569 100644 --- a/src/ontology/obi-edit.owl +++ b/src/ontology/obi-edit.owl @@ -679,16 +679,16 @@ https://sourceforge.net/tracker/?func=detail&aid=3603413&group_id=177891 - has_specified_input + has specified input see is_input_of example_of_usage - The inverse property of is_specified_input_of + The inverse property of is specified input of 8/17/09: specified inputs of one process are not necessarily specified inputs of a larger process that it is part of. This is in contrast to how 'has participant' works. PERSON: Alan Ruttenberg PERSON: Bjoern Peters PERSON: Larry Hunter PERSON: Melanie Coutot - has_specified_input + has specified input @@ -714,13 +714,13 @@ https://sourceforge.net/tracker/?func=detail&aid=3603413&group_id=177891 - is_specified_input_of + is specified input of some Autologous EBV(Epstein-Barr virus)-transformed B-LCL (B lymphocyte cell line) is_input_for instance of Chromum Release Assay described at https://wiki.cbil.upenn.edu/obiwiki/index.php/Chromium_Release_assay A relation between a planned process and a continuant participating in that process that is not created during the process. The presence of the continuant during the process is explicitly specified in the plan specification which the process realizes the concretization of. Alan Ruttenberg PERSON:Bjoern Peters - is_specified_input_of + is specified input of @@ -766,14 +766,14 @@ For instances: e has_quality q at t iff q inheres_in e at t and q instance-of Qu - has_specified_output + has specified output - The inverse property of is_specified_output_of + The inverse property of is specified output of PERSON: Alan Ruttenberg PERSON: Bjoern Peters PERSON: Larry Hunter PERSON: Melanie Courtot - has_specified_output + has specified output @@ -928,12 +928,12 @@ instance level relation [GOC:cjm] - is_specified_output_of + is specified output of A relation between a planned process and a continuant participating in that process. The presence of the continuant at the end of the process is explicitly specified in the objective specification which the process realizes the concretization of. Alan Ruttenberg PERSON:Bjoern Peters - is_specified_output_of + is specified output of diff --git a/src/ontology/templates/administration.tsv b/src/ontology/templates/administration.tsv index aed4b76d..591c8efe 100644 --- a/src/ontology/templates/administration.tsv +++ b/src/ontology/templates/administration.tsv @@ -2,7 +2,7 @@ ontology ID label editor preferred term has curation status alternative term def ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'realizes' some ('target of material addition role' and ('role of' some %)) SPLIT=| C 'realizes' some ('material to be added role' and ('role of' some %)) SPLIT=| C 'has part' some % SPLIT=| C achieves_planned_objective some % C % OBI:0000281 intraperitoneal injection intraperitoneal injection is the injection of a material entity (bearing the administered substance role) into the peritoneum (bearing the target role) of an organism using a syringe BP equivalent intraperitoneal administration ('realizes' some ('function' and ('inheres in' some 'syringe'))) OBI:0000429 intraperitoneal administration intraperitoneal administration The administration of a substance into the peritoneum of an organism Rats were injected intraperitoneally with either rrIL-6 (250 ng/0.5 ml) or equal-volume sterile saline twice within an interval of 24 h Person:Bjoern Peters equivalent administering substance in vivo peritoneum -OBI:0000837 oral ingestion of pill oral ingestion of pill An adding a material entity to target with the entity is a pill and the target is the mouth Person:Alan Ruttenberg 2009/09/28 Alan Ruttenberg. Fucoidan-use-case equivalent oral administration pill ('has_specified_input' some 'pill') +OBI:0000837 oral ingestion of pill oral ingestion of pill An adding a material entity to target with the entity is a pill and the target is the mouth Person:Alan Ruttenberg 2009/09/28 Alan Ruttenberg. Fucoidan-use-case equivalent oral administration pill ('has specified input' some 'pill') OBI:0000934 intramuscular injection intramuscular injection is the injection of a material entity (bearing the administered substance role) into the muscle (bearing the target role) of an organism using a syringe equivalent administering substance in vivo skeletal muscle tissue ('realizes' some ('function' and ('inheres in' some 'syringe'))) OBI:0000942 intradermal injection intradermal injection is the injection of a material entity (bearing the administered substance role) into the dermis (bearing the target role) of an organism using a syringe PERSON: Melanie Courtot equivalent administering substance in vivo dermis ('realizes' some ('function' and ('inheres in' some 'syringe'))) OBI:0000952 oral administration oral administration An administering substance in vivo into the mouth of an organism PERSON: Melanie Courtot equivalent administering substance in vivo mouth diff --git a/src/ontology/templates/antibody-purification.tsv b/src/ontology/templates/antibody-purification.tsv index 7227c734..955a911e 100644 --- a/src/ontology/templates/antibody-purification.tsv +++ b/src/ontology/templates/antibody-purification.tsv @@ -1,5 +1,5 @@ id rdfs label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent output -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester SPLIT=| A term tracker item SPLIT=| CLASS_TYPE C % C has_specified_output some % +ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester SPLIT=| A term tracker item SPLIT=| CLASS_TYPE C % C 'has specified output' some % OBI:0003616 antibody purification of MHC class I protein complex An antibody purification of MHC protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of MHC class I protein complex, while others contain impurities and are not of interest. Randi Vita Randi Vita|Sebastian Duesing equivalent antibody purification of MHC protein complex MHC class I protein complex OBI:0003617 antibody purification of human MHC class I protein complex An antibody purification of MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of human MHC class I protein complex, while others contain impurities and are not of interest. Randi Vita Randi Vita|Sebastian Duesing equivalent antibody purification of MHC class I protein complex human MHC class I protein complex OBI:0003618 antibody purification of HLA protein complex with A2 serotype An antibody purification of human MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of HLA protein complex with A2 serotype, while others contain impurities and are not of interest. Randi Vita Randi Vita|Sebastian Duesing equivalent antibody purification of human MHC class I protein complex HLA protein complex with A2 serotype diff --git a/src/ontology/templates/assays.tsv b/src/ontology/templates/assays.tsv index 8e146a7b..3bf66f7c 100644 --- a/src/ontology/templates/assays.tsv +++ b/src/ontology/templates/assays.tsv @@ -1,5 +1,5 @@ ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type logical note parent class material processing technique detection technique evaluant measurand analyte device reagent molecular label input output target entity target context objective associated axioms -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ( % and 'detection technique') SPLIT=| C (has_specified_input some (% and 'has role' some 'evaluant role')) and (realizes some ('evaluant role' and ('role of' some %))) SPLIT=| C (has_specified_input some %) and (realizes some ('measurand role' and ('inheres in' some %))) C (has_specified_input some %) and (realizes some ('analyte role' and ('inheres in' some %))) C (has_specified_input some %) and (realizes some (function and ('inheres in' some %))) SPLIT=| C (has_specified_input some %) and (realizes some ('reagent role' and ('inheres in' some %))) C (has_specified_input some %) and (realizes some ('molecular label role' and ('inheres in' some %))) C has_specified_input some % C has_specified_output some % C has_specified_output some ('is about' some %) C has_specified_output some ('is about' some ( 'has assay target context' some %)) C achieves_planned_objective some % C % +ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some (% and 'has role' some 'evaluant role')) and (realizes some ('evaluant role' and ('role of' some %))) SPLIT=| C ('has specified input' some %) and (realizes some ('measurand role' and ('inheres in' some %))) C ('has specified input' some %) and (realizes some ('analyte role' and ('inheres in' some %))) C ('has specified input' some %) and (realizes some (function and ('inheres in' some %))) SPLIT=| C ('has specified input' some %) and (realizes some ('reagent role' and ('inheres in' some %))) C ('has specified input' some %) and (realizes some ('molecular label role' and ('inheres in' some %))) C 'has specified input' some % C 'has specified output' some % C 'has specified output' some ('is about' some %) C 'has specified output' some ('is about' some ( 'has assay target context' some %)) C achieves_planned_objective some % C % CHMO:0000087 fluorescence microscopy assay fluorescence imaging|fluorescence microscopic imaging|FM Any type of light microscopy assay where the specimen can be made to fluoresce (emit energy as visible light) by illuminating it with light of specific wavelengths. These specimens are called fluorophores. CHMO subclass light microscopy assay ('material entity' and ('bearer of' some fluorescence)) CHMO:0000089 confocal fluorescence microscopy assay CLSM|confocal fluorescence imaging|confocal laser scanning fluorescence microscopy|confocal laser scanning microscopy|confocal-laser scanning microscopy|fluorescence confocal microscopy|fluorescence confocal scanning laser microscopy|LSCM|scanning confocal fluorescence microscopy Microscopy where the specimen can be made to fluoresce (emit energy as visible light) by scanning a gas (Ar or Kr) laser spot of specific wavelength over its surface and using a spatial pinhole to eliminate out-of-focus fluorescence. CHMO subclass microscopy assay CHMO:0000102 light microscopy assay light microscopy|OM|optical microscopy Microscopy where the specimen is illuminated with visible light and a system of lenses is used to produce an image. CHMO subclass microscopy assay @@ -47,7 +47,7 @@ OBI:0000743 immune response assay metadata incomplete An assay that determines OBI:0000748 bisulfite sequencing assay metadata complete A DNA methylation profiling assay which determines the methylation status of genomic DNA using DNA sequencing techniques preceded by a bisulfite based chemical modification of genomic DNA at CpG island location. url:https://en.wikipedia.org/wiki/Bisulfite_sequencing PMID: 19581485. High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing. Hodges E, Smith A, Kendall J, Xuan Z, Ravi K, Rooks M, Zhang M, Ye K, Battacharjee A, Brizuela L, McCombie WR, Wigler M, Hannon GJ, Hicks J. Philippe Rocca-Serra|Sagar Jain subclass DNA meth profiling is a epigenetic mod assay, does not need inference DNA methylation profiling assay DNA sequencing assay DNA extract ('deoxyribonucleotide' and ('has part' some 'methyl group')) DNA sequencer DNA extract ('measurement datum' and 'DNA sequence data') epigenetic modification identification objective OBI:0000787 human antithrombin-III in blood assay ready for release AT-III assay An assay that measures the amount of antithrombin III in blood. url:http://www.muschealth.com/lab/content.aspx?id=150006@2009/08/06 PMID:19696660#The antithrombin-III (AT-III) was determined using a Berichrom(r) Antithrombin-III (A) kit. Alan Ruttenberg subclass analyte assay ('scattered molecular aggregate' and ('has grain' some antithrombin-III)) scalar measurement datum blood coagulation OBI:0000802 prothrombin time assay metadata complete An assay that measures the prothrombin ratio, which is the prothrombin time for a patient, divided by the result for control plasma. Most commonly the test is preformed using blood plasma. Blood is drawn into a test tube containing liquid citrate, which acts as an anticoagulant. An excess of calcium is added to enable the blood to clot again.Tissue factor (also known as factor III or thromboplastin) is added, and the time the sample takes to clot is measured optically as the prothrombin time, which is compared to a control sample. url:http://en.wikipedia.org/wiki/Prothrombin_time@2009/10/06 PMID:19696660#The prothrombin time (PT) was quantitatively determined using RecombiPlasTin (Instrumentation Laboratory Company, Lexington, Massachusetts, USA). Alan Ruttenberg subclass assay scalar measurement datum blood coagulation -OBI:0000805 antithrombin-III berichrome assay metadata complete AT-III assay An antithrombin-III (AT-III) assay in which exogenous bovine thrombin and heparin are added to test plasma to form a thrombin-heparin-AT complex. The residual thrombin not bound then hydrolyzes the p-nitroalanine substrate to produce a yellow color, which is read at 405 nm. The intensity of color produced is inversely proportional to the AT present. A calibration is done with standard human plasma reagent and results for a given specimen are reported as a percentage relative to the standard url:http://www.clinchem.org/cgi/content/full/43/9/1783@2009/08/06 subclass human antithrombin-III in blood assay (has_specified_output some 'scalar measurement datum') and ('has participant' some 'Berichrom(r) Antithrombin III (A) Kit') and (has_specified_output exactly 1 Thing) +OBI:0000805 antithrombin-III berichrome assay metadata complete AT-III assay An antithrombin-III (AT-III) assay in which exogenous bovine thrombin and heparin are added to test plasma to form a thrombin-heparin-AT complex. The residual thrombin not bound then hydrolyzes the p-nitroalanine substrate to produce a yellow color, which is read at 405 nm. The intensity of color produced is inversely proportional to the AT present. A calibration is done with standard human plasma reagent and results for a given specimen are reported as a percentage relative to the standard url:http://www.clinchem.org/cgi/content/full/43/9/1783@2009/08/06 subclass human antithrombin-III in blood assay ('has specified output' some 'scalar measurement datum') and ('has participant' some 'Berichrom(r) Antithrombin III (A) Kit') and ('has specified output' exactly 1 Thing) OBI:0000808 spectrolyse heparin antifactor-Xa assay metadata complete An assay that quantitatively measures heparin in human plasma using Factor Xa and Antithrombin III in excess, where the rate of Factor Xa inhibition is directly proportional to the heparin concentration. The residual Factor Xa activity, measured with a Factor Xa-specific chromogenic substrate, is inversely proportional to the heparin concentration. url:http://www.kordia.nl/en/product/hemostasis/specialty_kits__reagens/598/spectrolyse_heparin_anti_xa@2009/08/06 PMID:19696660#Antifactor-Xa (anti-Xa) was determined using spectrolyse heparin (Xa) (Trinity Biotech plc, Bray, County Wicklow, Ireland). Alan Ruttenberg subclass assay scalar measurement datum blood coagulation OBI:0000812 measuring neural activity in the caudate nucleus assay metadata complete An assay that measures neural activity in the caudate nucleus Jessica Turner, NIF|Dirk Derom, OBI An SU micro-electrode was used to measure neural activity in the form of spike trains in the caudate nucleus of monkeys in response to a flashing light stimulus Helen Parkinson subclass extracellular electrophysiology recording assay OBI:0000820 activated partial thromboplastin time assay metadata complete aPTT assay An assay that evaluates blood coagulation by measuring the time required for the appearance of fibrin strands following the mixing blood or plasma with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of blood coaguation . It is used as a screening test and to monitor heparin therapy. url:http://www.ebi.ac.uk/ols/ontologies/efo/terms?short_form=EFO_0004310 The activated partial thromboplastin time (aPTT) was determined using Dade Actin FSL activated PTT reagent (PMID:19696660) Alan Ruttenberg|OBI call There is also the 'partial thromboplastin assay', which some people use synonymously to aPPT, but historically was done slightly differently (without adding a coagulant). subclass assay ('blood specimen' or 'blood plasma specimen') time measurement datum blood coagulation @@ -81,7 +81,7 @@ OBI:0000964 in live cell assay metadata incomplete An assay in which a measure OBI:0000966 in live organism assay metadata complete in vivo assay An assay in which a measurement is made by observing entities located in an organism. Measuring the rate in which cells that are pulsed with a peptide are killed inside a mouse by peptide specific cytotoxic T cells. Bjoern Peters subclass assay ('has participant' some ('material entity' and ('located in' some (organism and ('has quality' some alive))))) OBI:0000975 cell-cell binding detection by flow cytometry assay A binding assay which uses a flow cytometer to detect pairs of cells that are bound to each other by staining them with different fluorescent labels. IEDB Staining a B cell with PE and staining a T cell with FITC, incubating them together with a peptide, and counting the number of co-stained conjugates. IEDB equivalent cytometry assay flow cytometry assay binding OBI:0000978 in container assay metadata incomplete An assay in which a measurement is made by observing entities located in a container. subclass assay -OBI:0001001 Edinburgh handedness assay metadata complete An assay that uses a set of questions (the Edinburgh Handedness inventory) to generate a score that can be used to assess the dominance of a person's right or left hand in everyday activities. The inventory can be used by an observer assessing the person, or by a person self-reporting hand use. The latter method tends to be less reliable due to a person over-attributing tasks to the dominant hand. url:http://en.wikipedia.org/wiki/Edinburgh_Handedness_Inventory|PMID:5146491 Verdino (1998) Perceptual and Motor Skills. 86 (2): 476_8. (PMID: 9638746) uses this measure in an experimental study: ""Individuals of extreme handedness based on the Edinburgh Handedness Inventory (laterality Quotients of +90 to +100 and -100 and +54; 50 each)"" Alan Ruttenberg|Jessica Turner|Gully Burns (orcid:0000-0003-1493-865X) subclass handedness assay Homo sapiens Edinburgh score (has_specified_input value 'Edingburgh handedness inventory') +OBI:0001001 Edinburgh handedness assay metadata complete An assay that uses a set of questions (the Edinburgh Handedness inventory) to generate a score that can be used to assess the dominance of a person's right or left hand in everyday activities. The inventory can be used by an observer assessing the person, or by a person self-reporting hand use. The latter method tends to be less reliable due to a person over-attributing tasks to the dominant hand. url:http://en.wikipedia.org/wiki/Edinburgh_Handedness_Inventory|PMID:5146491 Verdino (1998) Perceptual and Motor Skills. 86 (2): 476_8. (PMID: 9638746) uses this measure in an experimental study: ""Individuals of extreme handedness based on the Edinburgh Handedness Inventory (laterality Quotients of +90 to +100 and -100 and +54; 50 each)"" Alan Ruttenberg|Jessica Turner|Gully Burns (orcid:0000-0003-1493-865X) subclass handedness assay Homo sapiens Edinburgh score ('has specified input' value 'Edingburgh handedness inventory') OBI:0001005 RNASE CL3 structure mapping assay ready for release single nucleotide resolution mapping assay using RNAse CL3 A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using RNAse CL3 as reagent and enzymatic probe. RNA ontology PMID:16453415 Philippe Rocca-Serra subclass single-nucleotide-resolution nucleic acid structure mapping assay using enzymatic probing RNA extract ribonuclease CL3 (chicken) secondary structure of RNA molecule OBI:0001006 CMCT structure mapping assay ready for release single nucleotide resolution mapping assay using CMCT probe A single-nucleotide-resolution nucleic acid structure mapping assay which uses CMCT as reagent and chemical probe to generate data and information at nucleotide resolution scale contributing to the determination of nucleic acid secondary structure RNA ontology PMID:2422386 and PMID:2446263 Philippe Rocca-Serra subclass single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing ('deoxyribonucleic acid' or 'ribonucleic acid') measurement datum secondary structure of sequence macromolecule OBI:0001008 MPE-Fe(II) structure mapping assay ready for release single nucleotide resolution mapping assay using Fe-MP probe A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at the nucleotide resolution scale using Fe-MP as reagent and chemical probe. RNA ontology PMID:6209709 Philippe Rocca-Serra subclass single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing RNA extract measurement datum secondary structure of RNA molecule diff --git a/src/ontology/templates/biopsy.tsv b/src/ontology/templates/biopsy.tsv index 3d8e352c..7a4d70c3 100644 --- a/src/ontology/templates/biopsy.tsv +++ b/src/ontology/templates/biopsy.tsv @@ -1,5 +1,5 @@ ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class material anatomical entity input device output entity -ID LABEL A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE CI C 'has_specified_input' some % C 'has_specified_input' some % C 'has_specified_output' some % +ID LABEL A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE CI C 'has specified input' some % C 'has specified input' some % C 'has specified output' some % OBI:0002650 biopsy ready for release A specimen collection that obtains a sample of tissue or cell from a living multicellular organism body for diagnostic purposes by means intended to be minimally invasive. https://en.wikipedia.org/wiki/Biopsy Biopsy of a potentially cancerous mole. Nicole Vasilevsky|Damion Dooley subclass collecting specimen from organism material anatomical entity device pre-mortem specimen OBI:0002651 image guided biopsy ready for release image-guided biopsy|imaging guided biopsy|image guided needle biopsy A biopsy which uses an imaging procedure to guide a needle biopsy. https://www.mayoclinic.org/diseases-conditions/cancer/in-depth/biopsy/art-20043922 Image-guided needle biopsy allows a doctor to biopsy suspicious areas that aren't readily seen or felt through skin, such as in a prostate gland. Damion Dooley subclass needle biopsy OBI:0002652 computed tomography assisted biopsy ready for release Computed Tomography Assisted Biopsy|CT Guided Biopsy|CT Assisted Biopsy|Computed Tomography-Guided Needle Biopsy A needle biopsy guided by real-time computed tomography (CT) scan images. http://purl.obolibrary.org/obo/NCIT_C137909 A CT Guided Biopsy is a procedure performed by a radiologist to obtain a small tissue sample through a needle. Damion Dooley subclass image guided biopsy computed tomography scanner diff --git a/src/ontology/templates/data-sets.tsv b/src/ontology/templates/data-sets.tsv index d1551234..57de9134 100644 --- a/src/ontology/templates/data-sets.tsv +++ b/src/ontology/templates/data-sets.tsv @@ -1,5 +1,5 @@ ontology ID label has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class is about is specified output of has member -ID A rdfs:label AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=, A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE CI C 'is about' some % C is_specified_output_of some % C 'has member' some % +ID A rdfs:label AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=, A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE CI C 'is about' some % C 'is specified output of' some % C 'has member' some % OBI:0003327 image data set A data set that is comprised of multidimensional structured measurements and metadata required for a morphological representation of an entity. An image data set can be the source from which an image (such as a 2D image using pixels or a 3D image using voxels) is produced. The output produced by a digital imaging technique, such as microscopy, MRI, or CT. https://orcid.org/0000-0001-9625-1899 ""William D. Duncan"",https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie"",https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik"",https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl"",https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra"",https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"" https://github.com/obi-ontology/obi/issues/1481 subclass data set entity OBI:0003328 magnetic resonance image data set An image data set whose information content originates from some MR imaging assay and is about some MRI participant. MRI at a Glance, ISBN 10: 1119053552 The DICOM file produced by an MRI machine when a multiple sclerosis patient undergoes a brain scan. https://orcid.org/0000-0001-9625-1899 ""William D. Duncan"",https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie"",https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik"",https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl"",https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra"",https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"" https://github.com/obi-ontology/obi/issues/1481 equivalent image data set magnetic resonance imaging participant OBI:0003331 raw image data set An image data set that encodes measurement values produced by some instrument before undergoing a data transformation. The untransformed (""k-space"") data produced by an MRI machine, prior to mathematical transformation into a form that corresponds to the anatomical structure of the brain. https://orcid.org/0000-0001-9625-1899 ""William D. Duncan"",https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie"",https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik"",https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl"",https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra"",https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"",https://orcid.org/0000-0002-1604-3078 ""Alan Ruttenberg"" https://github.com/obi-ontology/obi/issues/1481 subclass image data set diff --git a/src/ontology/templates/data-transformations.tsv b/src/ontology/templates/data-transformations.tsv index dbe7caa6..36179101 100644 --- a/src/ontology/templates/data-transformations.tsv +++ b/src/ontology/templates/data-transformations.tsv @@ -1,7 +1,7 @@ ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note term tracker item logical type parent class input output objective associated axioms -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A term tracker item CLASS_TYPE C % C has_specified_input some % C has_specified_output some % C achieves_planned_objective some % C % +ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A term tracker item CLASS_TYPE C % C 'has specified input' some % C 'has specified output' some % C achieves_planned_objective some % C % OBI:0003355 image data set analysis The process of deriving a data item from an image data set using computer algorithms. The produced data item can be an image data set, data measurement, or any other data item. https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik""|https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl""|https://orcid.org/0000-0001-9625-1899 ""William D. Duncan""|https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra""|https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie""|https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"" https://github.com/obi-ontology/obi/issues/1481 subclass data transformation image data set OBI:0003356 raw magnetic resonance image data set reconstruction A process that transforms raw magnetic resonance image data from an NMR/MRI machine into a reconstructed magnetic resonance image data set. A Fourier transform of raw ""k-space"" data produced into an image data set that represents the anatomical structure of the tissue examined. https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik""|https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl""|https://orcid.org/0000-0001-9625-1899 ""William D. Duncan""|https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra""|https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie""|https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"" https://github.com/obi-ontology/obi/issues/1481 equivalent image data set analysis raw magnetic resonance image data set reconstructed magnetic resonance image data set -OBI:0003647 tandem mass spectrometry analysis tandem mass spectrometry analysis A mass spectrometry analysis in which the data being analyzed is the result of a tandem mass spectrometry assay. Sebastian Duesing https://github.com/obi-ontology/obi/issues/1684 equivalent mass spectrometry analysis ('data item' and is_specified_output_of some 'tandem mass spectrometry assay') -OBI:0003648 liquid chromatrography mass spectrometry analysis liquid chromatography mass spectrometry analysis A mass spectrometry analysis in which the data being analyzed is the result of a liquid chromatography mass spectrometry assay. Sebastian Duesing https://github.com/obi-ontology/obi/issues/1684 equivalent mass spectrometry analysis ('data item' and is_specified_output_of some 'liquid chromatography mass spectrometry assay') -OBI:0003649 liquid chromatography-tandem mass spectrometry analysis liquid chromatography tandem mass spectrometry analysis A mass spectrometry analysis in which the data being analyzed is the result of a liquid chromatography tandem mass spectrometry assay. Sebastian Duesing https://github.com/obi-ontology/obi/issues/1684 equivalent mass spectrometry analysis ('data item' and is_specified_output_of some 'liquid chromatography-tandem mass spectrometry') +OBI:0003647 tandem mass spectrometry analysis tandem mass spectrometry analysis A mass spectrometry analysis in which the data being analyzed is the result of a tandem mass spectrometry assay. Sebastian Duesing https://github.com/obi-ontology/obi/issues/1684 equivalent mass spectrometry analysis ('data item' and 'is specified output of' some 'tandem mass spectrometry assay') +OBI:0003648 liquid chromatrography mass spectrometry analysis liquid chromatography mass spectrometry analysis A mass spectrometry analysis in which the data being analyzed is the result of a liquid chromatography mass spectrometry assay. Sebastian Duesing https://github.com/obi-ontology/obi/issues/1684 equivalent mass spectrometry analysis ('data item' and 'is specified output of' some 'liquid chromatography mass spectrometry assay') +OBI:0003649 liquid chromatography-tandem mass spectrometry analysis liquid chromatography tandem mass spectrometry analysis A mass spectrometry analysis in which the data being analyzed is the result of a liquid chromatography tandem mass spectrometry assay. Sebastian Duesing https://github.com/obi-ontology/obi/issues/1684 equivalent mass spectrometry analysis ('data item' and 'is specified output of' some 'liquid chromatography-tandem mass spectrometry') diff --git a/src/ontology/templates/devices.tsv b/src/ontology/templates/devices.tsv index df3f44ca..fb369a0e 100644 --- a/src/ontology/templates/devices.tsv +++ b/src/ontology/templates/devices.tsv @@ -309,7 +309,7 @@ OBI:0001204 SNP microarray SNP microarray metadata complete A DNA microarray us OBI:0001307 tiling microarray tiling microarray metadata complete genome tiling array A DNA microarray which has short fragments of nucleic acid immobilized on a substrate. These are designed to cover the whole genome of the target species. Tiling arrays are used to determine genome binding in ChIP assays or to identify transcribed regions. EFO_0002704: tiling array Person: Helen Parkinson DNA microarray OBI:0001865 assay array metadata complete A device made to be used in an analyte assay for immobilization of substances that bind the analyte at regular spatial positions on a surface. Penn Group PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg device solid support function OBI:0001869 Illumina BeadChip metadata complete An array that consists of 3-micron silica beads that self assemble in microwells on either of two materials: fiber optic bundles or planar silica slides. http://www.illumina.com/technology/beadarray_technology.ilmn PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg, Venkat Malladi assay array Illumina -OBI:0001870 Illumina methylation BeadChip metadata complete A BeadChip made for an analyte assay that generates information about DNA methylation. Penn Group PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg Illumina BeadChip ('bearer of' some (function and ('realized in' only (assay and (has_specified_output some ('measurement datum' and ('is about' some (deoxyribonucleotide and ('has part' some 'methyl group'))))))))) +OBI:0001870 Illumina methylation BeadChip metadata complete A BeadChip made for an analyte assay that generates information about DNA methylation. Penn Group PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg Illumina BeadChip ('bearer of' some (function and ('realized in' only (assay and ('has specified output' some ('measurement datum' and ('is about' some (deoxyribonucleotide and ('has part' some 'methyl group'))))))))) OBI:0001871 LSRFortessa X-20 metadata complete A flow cytometer analyzer manifactured by Becton ans Dickinson. Can be configured with up to 5 lasers, 488nm, 532 or 561 nm, 640 nm, 405 nm, 355 nm for measuring up to 20 parameters simultaneously. http://www.bdbiosciences.com/instruments/lsrx20/index.jsp?WT.srch=1&gclid=CJjJ8JTR5LoCFXBo7AodZycAbg Anna Maria Masci flow cytometer analyzer Becton Dickinson (BD Biosciences) OBI:0001971 Ion 316 Chip v2 Ion 316 Chip v2 Ion PGM 316 Chip|Ion 316 Chip|Ion PGM 316 Chip v2 An ion semiconductor chip manufactured by Life Technologies which detects polymerase-driven base incorporation to translate into digital form. The 316 chip is compatible with the Ion Torrent PGM and has a run time of: 3.0 hours for 200 bp reads with an output of 30-50 Mb, 4.9 hours for 400 bp reads with an output of 60 Mb-1 Gb. http://www.lifetechnologies.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-run-sequence/ion-pgm-ion-proton-system-chips.html PERSON: Sagar Jain Issue Tracker #774 https://sourceforge.net/p/obi/obi-terms/774/ ion semiconductor chip OBI:0001972 Ion 318 Chip v2 Ion 318 Chip v2 Ion 318 Chip|Ion PGM 318 Chip|Ion PGM 318 Chip v2 An ion semiconductor chip manufactured by Life Technologies which detects polymerase-driven base incorporation to translate into digital form. The 318 chip is compatible with the Ion Torrent PGM and has a run time of: 4.4 hours for 200 bp reads with an output of 60 Mb-1 Gb, 7.3 hours for 400 bp reads with an output of 1.2 Gb-2 Gb. http://www.lifetechnologies.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-run-sequence/ion-pgm-ion-proton-system-chips.html PERSON: Sagar Jain Issue Tracker #775 https://sourceforge.net/p/obi/obi-terms/775/ ion semiconductor chip diff --git a/src/ontology/templates/epitope-assays.tsv b/src/ontology/templates/epitope-assays.tsv index df7eb494..7e7bc676 100644 --- a/src/ontology/templates/epitope-assays.tsv +++ b/src/ontology/templates/epitope-assays.tsv @@ -1,5 +1,5 @@ Ontology ID label editor preferred term has curation status alternative term IEDB alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class material processing technique detection technique reagent input output MHC source target entity target context unit -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| A IEDB alternative term AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ( % and 'detection technique') SPLIT=| C (has_specified_input some %) and (realizes some ('reagent role' and ('inheres in' some %))) C has_specified_input some % C has_specified_output some % C has_specified_input some (% and ('has part' some 'MHC protein complex')) C has_specified_output some ('is about' some %) C has_specified_output some ('is about' some ( 'has assay target context' some %)) C has_specified_output some ('has measurement unit label' value %) +ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| A IEDB alternative term AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some %) and (realizes some ('reagent role' and ('inheres in' some %))) C 'has specified input' some % C 'has specified output' some % C 'has specified input' some (% and ('has part' some 'MHC protein complex')) C 'has specified output' some ('is about' some %) C 'has specified output' some ('is about' some ( 'has assay target context' some %)) C 'has specified output' some ('has measurement unit label' value %) OBI:0001194 ELISPOT assay measuring epitope specific transforming growth factor-beta production by T cells TGFb release|ELISPOT An enzyme-linked immunospot assay that detects transforming growth factor-beta production by T cells. IEDB PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters equivalent enzyme-linked immunospot assay ('transforming growth factor beta production' and ('process is result of' some 'MHC:epitope complex binding to TCR')) OBI:0001196 cytometric bead array assay measuring epitope specific IP-10 production by T cells CXCL10/IP-10 release|cytometric bead array A cytometric bead array assay that detects IP-10 production by T cells. IEDB PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters equivalent antigen detection by cytometric bead array assay ('IP-10 production' and ('process is result of' some 'MHC:epitope complex binding to TCR')) OBI:0001198 assay measuring epitope specific interleukin-27 production by T cells IL-27 release|biological activity A T cell epitope specific cytokine production assay that detects interleukin-27 production by T cells. IEDB PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters equivalent assay ('interleukin-27 production' and ('process is result of' some 'MHC:epitope complex binding to TCR')) diff --git a/src/ontology/templates/physical-examination.tsv b/src/ontology/templates/physical-examination.tsv index 7aeb49b3..ea2ebf3f 100644 --- a/src/ontology/templates/physical-examination.tsv +++ b/src/ontology/templates/physical-examination.tsv @@ -1,5 +1,5 @@ ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type logical note parent class detection technique evaluant device input output anatomical site assessed biological trait -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some ( % and 'detection technique') SPLIT=| C (has_specified_input some (% and 'has role' some 'evaluant role')) and (realizes some ('evaluant role' and ('role of' some %))) SPLIT=| C (has_specified_input some %) and (realizes some (function and ('inheres in' some %))) SPLIT=| C has_specified_input some % C has_specified_output some % C has_specified_output some ('is about' some %) C has_specified_output some ('is quality measurement of' some %) +ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some (% and 'has role' some 'evaluant role')) and (realizes some ('evaluant role' and ('role of' some %))) SPLIT=| C ('has specified input' some %) and (realizes some (function and ('inheres in' some %))) SPLIT=| C 'has specified input' some % C 'has specified output' some % C 'has specified output' some ('is about' some %) C 'has specified output' some ('is quality measurement of' some %) OBI:0003501 functional assessment of individual A physical examination of an organism's ability to perform functional activities. Critical Path Institute Daniel Olson, ORCID: 0000-0002-8134-1207 https://github.com/obi-ontology/obi/issues/1637 subclass physical examination of an organism OBI:0003502 facial atrophy assessment An observational assessment of the loss of facial muscle tissue due to inactivity or disease. Critical Path Institute Daniel Olson, ORCID: 0000-0002-8134-1207 https://github.com/obi-ontology/obi/issues/1637 subclass observational assessment of individual facial muscle facial muscle performance OBI:0003503 tongue atrophy assessment An observational assessment of the loss of muscle tissue related to tongue movement due to inactivity or disease. Critical Path Institute Daniel Olson, ORCID: 0000-0002-8134-1207 https://github.com/obi-ontology/obi/issues/1637 subclass observational assessment of individual tongue facial muscle performance diff --git a/src/ontology/templates/sample-collection.tsv b/src/ontology/templates/sample-collection.tsv index c2731ddf..34df2de5 100644 --- a/src/ontology/templates/sample-collection.tsv +++ b/src/ontology/templates/sample-collection.tsv @@ -1,5 +1,5 @@ ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class specimen type -ID LABEL A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C has_specified_output some (% and 'has role' some 'specimen role') +ID LABEL A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has specified output' some (% and 'has role' some 'specimen role') OBI:0002904 adult arthropod specimen collection process collection of adults A live arthropod specimen collection process in which the arthropods are in the adult stage. MIRO:30000052 John Judkins https://github.com/obi-ontology/obi/issues/1217 live arthropod specimen collection process OBI:0002905 animal-biting arthropod specimen collection by aspiration animal biting catch An arthropod specimen collection by aspiration that occurs while the arthropod is biting an animal. MIRO:30000012 John Judkins https://github.com/obi-ontology/obi/issues/1217 arthropod specimen collection by aspiration OBI:0002906 animal-biting outdoor arthropod specimen collection by aspiration animal biting catch - outdoors An animal-biting arthropod specimen collection by aspiration that occurs outside a building. MIRO:30000014 John Judkins https://github.com/obi-ontology/obi/issues/1217 animal-biting arthropod specimen collection by aspiration diff --git a/src/ontology/templates/sequence-analysis.tsv b/src/ontology/templates/sequence-analysis.tsv index 9fb69b27..09ce802a 100644 --- a/src/ontology/templates/sequence-analysis.tsv +++ b/src/ontology/templates/sequence-analysis.tsv @@ -1,5 +1,5 @@ ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class output input input of output of objective -ID A rdfs:label A editor preferred term AL has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has_specified_output' some % C 'has_specified_input' some % C is_specified_input_of some % C is_specified_output_of some % C achieves_planned_objective some % +ID A rdfs:label A editor preferred term AL has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has specified output' some % C 'has specified input' some % C 'is specified input of' some % C 'is specified output of' some % C achieves_planned_objective some % OBI:0002565 adapter-sequence trimming A data transformation in which adapter sequences at the end of a molecular sequence are cut (removed). Dan Berrios Dan Berrios subclass sequence trimming adapter-trimmed sequence data 'adapter sequence data' OBI:0002566 file merge A data transformation in which data contained in 2 or more files are merged into a single file. Dan Berrios Dan Berrios subclass data transformation OBI:0002567 sequence alignment A data transformation in which one or more sequences (reads) are positioned on a reference sequence template (often a reference set of genes), according to the genetic base-pairing paradigm. Dan Berrios Dan Berrios subclass sequence analysis data transformation aligned sequence data sequence data diff --git a/src/ontology/templates/specimen-assay-data.tsv b/src/ontology/templates/specimen-assay-data.tsv index 84caaf7d..6bb77a2c 100644 --- a/src/ontology/templates/specimen-assay-data.tsv +++ b/src/ontology/templates/specimen-assay-data.tsv @@ -1,22 +1,22 @@ ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item axiom ID LABEL A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item EC % -OBI:0003243 blood assay datum A data item that is the specified output of a blood assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and is_specified_output_of some 'blood assay') -OBI:0003244 blood microbiology datum An organism detection datum that is the specified output of a blood microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and is_specified_output_of some 'blood microbiology assay') -OBI:0003245 feces assay datum A data item that is the specified output of a feces assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and is_specified_output_of some 'feces assay') -OBI:0003246 feces microbiology datum An organism detection datum that is the specified output of a feces microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and is_specified_output_of some 'feces microbiology assay') -OBI:0003247 urine assay datum A data item that is the specified output of a urine assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and is_specified_output_of some 'urine assay') -OBI:0003248 urine microbiology datum An organism detection datum that is the specified output of a urine microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and is_specified_output_of some 'urine microbiology assay') -OBI:0003249 induced sputum assay datum A data item that is the specified output of a induced sputum assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and is_specified_output_of some 'induced sputum assay') -OBI:0003251 induced sputum microbiology datum An organism detection datum that is the specified output of an induced sputum microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and is_specified_output_of some 'induced sputum microbiology assay') -OBI:0003252 cerebrospinal fluid assay datum A data item that is the specified output of a cerebrospinal fluid assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and is_specified_output_of some 'cerebrospinal fluid assay') -OBI:0003253 cerebrospinal fluid microbiology datum An organism detection datum that is the specified output of a cerebrospinal fluid microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and is_specified_output_of some 'cerebrospinal fluid microbiology assay') -OBI:0003254 endotracheal aspirate assay datum An organism detection datum that is the specified output of an endotracheal aspirate assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and is_specified_output_of some 'endotracheal aspirate assay') -OBI:0003255 endotracheal tube aspirate microbiology datum An organism detection datum that is the specified output of an endotracheal tube aspirate microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and is_specified_output_of some 'endotracheal tube aspirate microbiology assay') -OBI:0003256 lung microbiology datum An organism detection datum that is the specified output of a lung microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and is_specified_output_of some 'lung microbiology assay') -OBI:0003257 nasopharyngeal or oropharyngeal swab microbiology datum An organism detection datum that is the specified output of a nasopharyngeal or oropharyngeal swab microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and is_specified_output_of some 'nasopharyngeal or oropharyngeal swab microbiology assay') -OBI:0003258 pleural fluid microbiology datum An organism detection datum that is the specified output of a pleural fluid microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and is_specified_output_of some 'pleural fluid microbiology assay') -OBI:0003259 umbilical cord blood assay datum A data item that is the specified output of an umbilical cord blood assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and is_specified_output_of some 'umbilical cord blood assay') -OBI:0003260 umbilical cord blood microbiology datum An organism detection datum that is the specified output of an umbilical cord blood microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and is_specified_output_of some 'umbilical cord blood microbiology assay') +OBI:0003243 blood assay datum A data item that is the specified output of a blood assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and 'is specified output of' some 'blood assay') +OBI:0003244 blood microbiology datum An organism detection datum that is the specified output of a blood microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and 'is specified output of' some 'blood microbiology assay') +OBI:0003245 feces assay datum A data item that is the specified output of a feces assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and 'is specified output of' some 'feces assay') +OBI:0003246 feces microbiology datum An organism detection datum that is the specified output of a feces microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and 'is specified output of' some 'feces microbiology assay') +OBI:0003247 urine assay datum A data item that is the specified output of a urine assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and 'is specified output of' some 'urine assay') +OBI:0003248 urine microbiology datum An organism detection datum that is the specified output of a urine microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and 'is specified output of' some 'urine microbiology assay') +OBI:0003249 induced sputum assay datum A data item that is the specified output of a induced sputum assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and 'is specified output of' some 'induced sputum assay') +OBI:0003251 induced sputum microbiology datum An organism detection datum that is the specified output of an induced sputum microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and 'is specified output of' some 'induced sputum microbiology assay') +OBI:0003252 cerebrospinal fluid assay datum A data item that is the specified output of a cerebrospinal fluid assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and 'is specified output of' some 'cerebrospinal fluid assay') +OBI:0003253 cerebrospinal fluid microbiology datum An organism detection datum that is the specified output of a cerebrospinal fluid microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and 'is specified output of' some 'cerebrospinal fluid microbiology assay') +OBI:0003254 endotracheal aspirate assay datum An organism detection datum that is the specified output of an endotracheal aspirate assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and 'is specified output of' some 'endotracheal aspirate assay') +OBI:0003255 endotracheal tube aspirate microbiology datum An organism detection datum that is the specified output of an endotracheal tube aspirate microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and 'is specified output of' some 'endotracheal tube aspirate microbiology assay') +OBI:0003256 lung microbiology datum An organism detection datum that is the specified output of a lung microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and 'is specified output of' some 'lung microbiology assay') +OBI:0003257 nasopharyngeal or oropharyngeal swab microbiology datum An organism detection datum that is the specified output of a nasopharyngeal or oropharyngeal swab microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and 'is specified output of' some 'nasopharyngeal or oropharyngeal swab microbiology assay') +OBI:0003258 pleural fluid microbiology datum An organism detection datum that is the specified output of a pleural fluid microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and 'is specified output of' some 'pleural fluid microbiology assay') +OBI:0003259 umbilical cord blood assay datum A data item that is the specified output of an umbilical cord blood assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and 'is specified output of' some 'umbilical cord blood assay') +OBI:0003260 umbilical cord blood microbiology datum An organism detection datum that is the specified output of an umbilical cord blood microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and 'is specified output of' some 'umbilical cord blood microbiology assay') OBI:0003261 bacteria in blood datum A blood microbiology datum that is about bacteria. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('blood microbiology datum' and 'is about' some Bacteria) OBI:0003262 virus in blood datum A blood microbiology datum that is about a virus. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('blood microbiology datum' and 'is about' some Viruses) OBI:0003263 eukaryota in blood datum A blood microbiology datum that is about eukaryota. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('blood microbiology datum' and 'is about' some Eukaryota) @@ -38,12 +38,12 @@ OBI:0003278 bacteria in pleural fluid datum A pleural fluid microbiology datu OBI:0003279 eukaryota in pleural fluid datum A pleural fluid microbiology datum that is about eukaryota. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('pleural fluid microbiology datum' and 'is about' some Eukaryota) OBI:0003280 virus in pleural fluid datum A pleural fluid microbiology datum that is about a virus. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('pleural fluid microbiology datum' and 'is about' some Viruses) OBI:0003281 eukaryota in umbilical cord blood datum An umbilical cord blood microbiology datum that is about eukaryota. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('umbilical cord blood microbiology datum' and 'is about' some Eukaryota) -OBI:0003365 milk assay datum A data item that is the specified output of a milk assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1515 ('data item' and is_specified_output_of some 'milk assay') -OBI:0003382 placental blood microbiology datum An organism detection datum that is the specified output of a placental blood microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1297 ('organism detection datum' and is_specified_output_of some 'placental blood microbiology assay') +OBI:0003365 milk assay datum A data item that is the specified output of a milk assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1515 ('data item' and 'is specified output of' some 'milk assay') +OBI:0003382 placental blood microbiology datum An organism detection datum that is the specified output of a placental blood microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1297 ('organism detection datum' and 'is specified output of' some 'placental blood microbiology assay') OBI:0003383 eukaryota in placental blood datum A placental blood microbiology datum that is about eukaryota. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1297 ('placental blood microbiology datum' and 'is about' some Eukaryota) -OBI:0003417 antigen specific antibodies assay datum A data item that is the specified output of an antigen specific antibodies assay. VEuPathDB John Judkins ORCID:0000-0001-6595-0902 https://github.com/obi-ontology/obi/issues/1526 ('data item' and is_specified_output_of some 'antigen specific antibodies assay') -OBI:0003420 antigen specific antibodies in blood assay datum An antigen specific antibodies assay datum that is the specified output of an antigen specific antibodies in blood assay. VEuPathDB John Judkins ORCID:0000-0001-6595-0902 https://github.com/obi-ontology/obi/issues/1526 ('antigen specific antibodies assay datum' and is_specified_output_of some 'blood assay') -OBI:0003421 antigen specific antibodies in milk assay datum An antigen specific antibodies assay datum that is the specified output of an antigen specific antibodies in milk assay. VEuPathDB John Judkins ORCID:0000-0001-6595-0902 https://github.com/obi-ontology/obi/issues/1526 ('antigen specific antibodies assay datum' and is_specified_output_of some 'milk assay') -OBI:0003577 skin of body microbiology datum An organism detection datum that is the specified output of a skin of body microbiology assay. VEuPathDB John Judkins ORCID:0000-0001-6595-0902 https://github.com/obi-ontology/obi/issues/1680 ('organism detection datum' and is_specified_output_of some 'skin of body microbiology assay') -OBI:0003579 bone marrow microbiology datum An organism detection datum that is the specified output of a bone marrow microbiology assay. VEuPathDB John Judkins ORCID:0000-0001-6595-0902 https://github.com/obi-ontology/obi/issues/1680 ('organism detection datum' and is_specified_output_of some 'bone marrow microbiology assay') -OBI:0003581 nasal aspirate microbiology datum An organism detection datum that is the specified output of a nasal aspirate microbiology assay. VEuPathDB John Judkins ORCID:0000-0001-6595-0902 https://github.com/obi-ontology/obi/issues/1680 ('organism detection datum' and is_specified_output_of some 'nasal aspirate microbiology assay') +OBI:0003417 antigen specific antibodies assay datum A data item that is the specified output of an antigen specific antibodies assay. VEuPathDB John Judkins ORCID:0000-0001-6595-0902 https://github.com/obi-ontology/obi/issues/1526 ('data item' and 'is specified output of' some 'antigen specific antibodies assay') +OBI:0003420 antigen specific antibodies in blood assay datum An antigen specific antibodies assay datum that is the specified output of an antigen specific antibodies in blood assay. VEuPathDB John Judkins ORCID:0000-0001-6595-0902 https://github.com/obi-ontology/obi/issues/1526 ('antigen specific antibodies assay datum' and 'is specified output of' some 'blood assay') +OBI:0003421 antigen specific antibodies in milk assay datum An antigen specific antibodies assay datum that is the specified output of an antigen specific antibodies in milk assay. VEuPathDB John Judkins ORCID:0000-0001-6595-0902 https://github.com/obi-ontology/obi/issues/1526 ('antigen specific antibodies assay datum' and 'is specified output of' some 'milk assay') +OBI:0003577 skin of body microbiology datum An organism detection datum that is the specified output of a skin of body microbiology assay. VEuPathDB John Judkins ORCID:0000-0001-6595-0902 https://github.com/obi-ontology/obi/issues/1680 ('organism detection datum' and 'is specified output of' some 'skin of body microbiology assay') +OBI:0003579 bone marrow microbiology datum An organism detection datum that is the specified output of a bone marrow microbiology assay. VEuPathDB John Judkins ORCID:0000-0001-6595-0902 https://github.com/obi-ontology/obi/issues/1680 ('organism detection datum' and 'is specified output of' some 'bone marrow microbiology assay') +OBI:0003581 nasal aspirate microbiology datum An organism detection datum that is the specified output of a nasal aspirate microbiology assay. VEuPathDB John Judkins ORCID:0000-0001-6595-0902 https://github.com/obi-ontology/obi/issues/1680 ('organism detection datum' and 'is specified output of' some 'nasal aspirate microbiology assay') diff --git a/src/ontology/templates/specimens.tsv b/src/ontology/templates/specimens.tsv index 28cc0148..934e7a7d 100644 --- a/src/ontology/templates/specimens.tsv +++ b/src/ontology/templates/specimens.tsv @@ -1,5 +1,5 @@ ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class specimen collection process gross anatomical part collection process input associated axioms URI -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C is_specified_output_of some % C (is_specified_output_of some 'specimen collection process') and ('derives from' some %) C is_specified_output_of some ('specimen collection process' and has_specified_input some %) C % SPLIT=| +ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'is specified output of' some % C ('is specified output of' some 'specimen collection process') and ('derives from' some %) C 'is specified output of' some ('specimen collection process' and 'has specified input' some %) C % SPLIT=| OBI:0000651 urine specimen urine specimen metadata complete a portion of urine collected from an organism This could be instead a kind of collection of secreted stuff. Among secreted stuff there is passive, and active. urine is secreted, passiv. lavage is secreted, active|are we happy calling collection of urine a material separation?|4/10/2011BP: It seems to me that the editor notes refer to a previous version, and are no longer relevant. equivalent specimen from organism collecting specimen from organism urine OBI:0000655 blood specimen blood specimen ready for release a material entity derived from a portion of blood collected from an organism Bjoern Peters blood drawn from a human for glucose assay Bjoern Peters equivalent specimen from organism collecting specimen from organism blood OBI:0000671 sample from organism sample from organism example to be eventually removed a material obtained from an organism in order to be a representative of the whole we need to work on this: Is taking a urine sample a material separation process? If not, we will need to specify what 'taking a sample from organism' entails. We can argue that the objective to obtain a urine sample from a patient is enough to call it a material separation process, but it could dilute what material separation was supposed to be about.|5/29: This is a helper class for now equivalent specimen from organism 'has role' some 'material sample role' @@ -14,23 +14,23 @@ OBI:0000880 RNA extract RNA extract metadata complete an extract which is the o OBI:0000895 total RNA extract total RNA extract metadata complete A RNA extract that is the output of an extraction process in which total celluar and organelle RNA molecules are isolated from a specimen. UPenn Group Extraction of total RNA from cells with Qiagen mini RNeasy kit PERSON: Chris Stoeckert|PERSON: Jie Zheng subclass RNA extract total RNA extraction OBI:0000899 organellar RNA extract organellar RNA extract metadata complete A RNA extract that is the output of an extraction process in which RNA molecules found in an organelle, e.g., mitochondrion, ER, or chloroplast, excluding the nucleus, are extracted. UPenn Group Extraction of organellar RNA from plant cells using organellar RNA binding protein. PERSON: Chris Stoeckert|PERSON: Jie Zheng subclass RNA extract organellar RNA extraction OBI:0000902 post mortem specimen post mortem specimen metadata complete a specimen that was taken from a dead organism MO_416 postmortem the spleen taken from a dead mouse Bjoern Peters equivalent specimen with pre- or post-mortem status ('organism' and ('has quality' some 'dead')) -OBI:0000908 labeled DNA extract labeled DNA extract metadata complete a labeled specimen that is the output of a labeling process and has grain labeled DNA to be able to detect DNA in future experiments. Group: OBI group Group: OBI group Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. Added duirng Mar 1, 2010 dev call equivalent labeled nucleic acid extract ('addition of molecular label' and ('has_specified_input' some 'DNA extract')) 'has grain' some 'deoxyribonucleic acid' +OBI:0000908 labeled DNA extract labeled DNA extract metadata complete a labeled specimen that is the output of a labeling process and has grain labeled DNA to be able to detect DNA in future experiments. Group: OBI group Group: OBI group Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. Added duirng Mar 1, 2010 dev call equivalent labeled nucleic acid extract ('addition of molecular label' and ('has specified input' some 'DNA extract')) 'has grain' some 'deoxyribonucleic acid' OBI:0000909 cloacal specimen cell specimen metadata complete A specimen obtained by inserting a swab deeply into the vent of the cloaca of an organism and vigorously swabbing the wall. The swab should be deeply stained with fecal material and is then placed in transport medium. WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf type of sample used in the PCIRN influenza network PERSON: Melanie Courtot equivalent specimen from organism collecting specimen from organism cloaca OBI:0000914 nasopharyngeal aspirate specimen nasopharyngeal aspirate specimen metadata complete A specimen which derives from nasopharyngeal mucosa after aspiration. WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf type of sample used in the PCIRN influenza network PERSON: Melanie Courtot subclass specimen from organism collecting specimen from organism nasopharynx OBI:0000917 nasal swab specimen nasal swab specimen metadata complete A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of exudate and epithelial debris for microbiological or cellular examination. WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf type of sample used in the PCIRN influenza network PERSON: Melanie Courtot equivalent specimen from organism collecting specimen with swab nasal cavity mucosa -OBI:0000921 labeled RNA extract labeled RNA extract metadata complete a labeled specimen that is the output of a labeling process and has grain labeled RNA to be able to detect RNA in future experiments. Group: OBI group Group: OBI group Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. Added duirng Mar 1, 2010 dev call equivalent labeled nucleic acid extract ('addition of molecular label' and ('has_specified_input' some 'RNA extract')) 'has grain' some 'ribonucleic acid' -OBI:0000922 frozen specimen frozen specimen metadata incomplete A specimen that has been frozen in order to store it. MO_610 frozen_sample Frozen blood plasma Person:Alan Ruttenberg equivalent specimen ('freezing storage' and ('has_specified_input' some ('has role' some 'specimen role'))) +OBI:0000921 labeled RNA extract labeled RNA extract metadata complete a labeled specimen that is the output of a labeling process and has grain labeled RNA to be able to detect RNA in future experiments. Group: OBI group Group: OBI group Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. Added duirng Mar 1, 2010 dev call equivalent labeled nucleic acid extract ('addition of molecular label' and ('has specified input' some 'RNA extract')) 'has grain' some 'ribonucleic acid' +OBI:0000922 frozen specimen frozen specimen metadata incomplete A specimen that has been frozen in order to store it. MO_610 frozen_sample Frozen blood plasma Person:Alan Ruttenberg equivalent specimen ('freezing storage' and ('has specified input' some ('has role' some 'specimen role'))) OBI:0000924 labeled specimen labeled specimen metadata incomplete A specimen that has been modified in order to be able to detect it in future experiments OBI group added during call 3/1/2010 equivalent specimen addition of molecular label 'has part' some 'molecular label' -OBI:0000950 paraffin specimen paraffin specimen metadata incomplete a specimen that is output of a paraffin storage process in which specimen is embedded in paraffin MO_990 paraffin_sample liver tissue embedded in paraffin PERSON: Chris Stoeckert|PERSON: Jie Zheng equivalent specimen ('paraffin storage' and ('has_specified_input' some ('has role' some 'specimen role'))) +OBI:0000950 paraffin specimen paraffin specimen metadata incomplete a specimen that is output of a paraffin storage process in which specimen is embedded in paraffin MO_990 paraffin_sample liver tissue embedded in paraffin PERSON: Chris Stoeckert|PERSON: Jie Zheng equivalent specimen ('paraffin storage' and ('has specified input' some ('has role' some 'specimen role'))) OBI:0000953 processed specimen processed specimen ready for release A specimen that has been intentionally physically modified. Bjoern Peters Bjoern Peters A tissue sample that has been sliced and stained for a histology study. equivalent specimen 'processed material' and 'specimen' -OBI:0000965 lyophilized specimen lyophilized specimen metadata incomplete a specimen that is output of a lyophilization storage process in which specimen is lyophilized for storage. MO_589 freeze_dried_sample freezing dried DNA PERSON: Chris Stoeckert|PERSON: Jie Zheng equivalent specimen ('lyophilization storage' and ('has_specified_input' some ('has role' some 'specimen role'))) +OBI:0000965 lyophilized specimen lyophilized specimen metadata incomplete a specimen that is output of a lyophilization storage process in which specimen is lyophilized for storage. MO_589 freeze_dried_sample freezing dried DNA PERSON: Chris Stoeckert|PERSON: Jie Zheng equivalent specimen ('lyophilization storage' and ('has specified input' some ('has role' some 'specimen role'))) OBI:0000971 fresh specimen fresh specimen metadata incomplete a specimen that is output of a specimen creation process used for an investigation without storage. MO_730 fresh_sample a liver freshly removed from a rat PERSON: Chris Stoeckert|PERSON: Jie Zheng subclass specimen with known storage state -OBI:0000981 agar stab specimen agar stab specimen metadata incomplete a specimen that is output of a process that cell culture inoculated into agar for long term storage. MO_971 agar_stab PERSON: Chris Stoeckert|PERSON: Jie Zheng equivalent specimen ('agar stab storage' and ('has_specified_input' some ('has role' some 'specimen role'))) +OBI:0000981 agar stab specimen agar stab specimen metadata incomplete a specimen that is output of a process that cell culture inoculated into agar for long term storage. MO_971 agar_stab PERSON: Chris Stoeckert|PERSON: Jie Zheng equivalent specimen ('agar stab storage' and ('has specified input' some ('has role' some 'specimen role'))) OBI:0001010 nucleic acid extract nucleic acid extract metadata complete An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen. UPenn Group Person: Jie Zheng subclass specimen nucleic acid extraction OBI:0001051 DNA extract DNA extract metadata complete The output of an extraction process in which DNA molecules are purified in order to exclude DNA from organellas. Group: UPenn group Person: Jie Zheng subclass nucleic acid extract DNA extraction 'has grain' some 'deoxyribonucleic acid' -OBI:0001143 labeled nucleic acid extract labeled nucleic acid extract metadata complete labeled extract a labeled specimen that is the output of a labeling process and has grain labeled nucleic acid for detection of the nucleic acid in future experiments. MO_221 labeledExtract Person: Jie Zheng equivalent labeled specimen ('addition of molecular label' and ('has_specified_input' some 'nucleic acid extract')) 'has grain' some 'nucleic acid' +OBI:0001143 labeled nucleic acid extract labeled nucleic acid extract metadata complete labeled extract a labeled specimen that is the output of a labeling process and has grain labeled nucleic acid for detection of the nucleic acid in future experiments. MO_221 labeledExtract Person: Jie Zheng equivalent labeled specimen ('addition of molecular label' and ('has specified input' some 'nucleic acid extract')) 'has grain' some 'nucleic acid' OBI:0001468 cell specimen cell specimen metadata incomplete A specimen primarily composed of a cell or cells collected from a multicellular organism or a cell culture. MO_612 cell PERSON: Chris Stoeckert, Jie Zheng, Alexander Diehl Discussed on obi call Jan 23, 2017. To improve cell specimen that include single cell specimen. Details see tracker: https://sourceforge.net/p/obi/obi-terms/828 equivalent specimen from organism 'has part' some 'cell' -OBI:0001472 specimen with known storage state specimen with known storage state metadata incomplete A specimen for which it is known whether it has been subjected to storage of a specified type. MO_95 BiosourceType PERSON: Chris Stoeckert, Jie Zheng equivalent specimen 'fresh specimen' or ('specimen' and ('is_specified_output_of' some 'storage')) +OBI:0001472 specimen with known storage state specimen with known storage state metadata incomplete A specimen for which it is known whether it has been subjected to storage of a specified type. MO_95 BiosourceType PERSON: Chris Stoeckert, Jie Zheng equivalent specimen 'fresh specimen' or ('specimen' and ('is specified output of' some 'storage')) OBI:0001479 specimen from organism ready for release tissue specimen A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm). MO_954 organism_part PERSON: Chris Stoeckert, Jie Zheng equivalent specimen ('organism' or 'material anatomical entity' or 'anatomical cluster') OBI:0001506 specimen with pre- or post-mortem status specimen with pre- or post-mortem status metadata complete A specimen that has been established to be taken from a live (pre-mortem) or dead (post-mortem) organism. MO_84 OrganismStatus PERSON: Chris Stoeckert, Jie Zheng organizational term, used in description of specimen that is created from known pre- or post-mortem status equivalent specimen ('organism' and ('has quality' some ('alive' or 'dead'))) OBI:0002125 H&E-stained fixed tissue slide specimen H&E-stained fixed tissue slide specimen pending final vetting A fixed tissue slide specimen that is the output of H&E slide staining. OBIB, OBI Chris Stoeckert, Ned Haubein equivalent fixed tissue slide specimen H&E slide staining @@ -128,13 +128,13 @@ OBI:0003595 nasal lavage fluid A specimen collected through nasal cavity lava OBI:0003652 albumin-free serum albumin-free serum A blood serum specimen that contains no albumin. Sebastian Duesing Philippe Rocca-Serra https://github.com/obi-ontology/obi/issues/493 equivalent blood serum specimen 'has part' only (not ('albumin')) OBI:0003666 lavage fluid specimen lavage fluid specimen A specimen obtained through a lavage process which includes fluid in addition to cells and/or cellular secretions. The collection of bronchoalveolar lavage fluid (BAL) from the lungs of mice in order to study the cytokines present. Sebastian Duesing https://github.com/obi-ontology/obi/issues/1803 equivalent specimen from organism lavage OBI:0003667 oral lavage fluid oral lavage fluid mouth rinse specimen A specimen collected through oral cavity lavage that contains the reagents used to for the lavage process, organisms, cells, cellular secretions, and other biomaterials present in the oral cavity space. Sebastian Duesing Anna Maria Masci https://github.com/obi-ontology/obi/issues/1803 equivalent lavage fluid specimen lavage mouth UBERON_0000165 -OBI:0100016 blood plasma specimen blood plasma specimen metadata complete plasma a material entity which corresponds to the liquid component of blood, in which the blood cells are suspended. WEB: http://en.wikipedia.org/wiki/Blood_plasma PMID: 18217225.Sex Transm Dis. 2008 Jan;35(1):55-60. Review.Human immunodeficiency virus viral load in blood plasma and semen: review and implications of empirical findings. PERSON: Maura Gasparetto|PERSON: Melanie Courtot|PERSON: Philippe Rocca-Serra 03/21/2010: BP, blood plasma is defined as the output of certain separation processes, so this is in the domain of OBI, not FMA. subclass blood specimen ('material component separation' and ('has_specified_input' some 'blood specimen')) -OBI:0100017 blood serum specimen blood serum specimen metadata complete A material entity which derives from blood and corresponds to blood plasma without fibrinogen or the other clotting factors. WEB: http://en.wikipedia.org/wiki/Blood_plasma PMID: 18229666.Adv Med Sci. 2007;52 Suppl 1:204-6.Antioxidant activity of blood serum and saliva in patients with periodontal disease treated due to epilepsy. PERSON: Maura Gasparetto|PERSON: Melanie Courtot|PERSON: Philippe Rocca-Serra subclass blood plasma specimen (('filtration' or 'centrifugation' or 'dialysis') and ('has_specified_input' some 'blood specimen')) +OBI:0100016 blood plasma specimen blood plasma specimen metadata complete plasma a material entity which corresponds to the liquid component of blood, in which the blood cells are suspended. WEB: http://en.wikipedia.org/wiki/Blood_plasma PMID: 18217225.Sex Transm Dis. 2008 Jan;35(1):55-60. Review.Human immunodeficiency virus viral load in blood plasma and semen: review and implications of empirical findings. PERSON: Maura Gasparetto|PERSON: Melanie Courtot|PERSON: Philippe Rocca-Serra 03/21/2010: BP, blood plasma is defined as the output of certain separation processes, so this is in the domain of OBI, not FMA. subclass blood specimen ('material component separation' and ('has specified input' some 'blood specimen')) +OBI:0100017 blood serum specimen blood serum specimen metadata complete A material entity which derives from blood and corresponds to blood plasma without fibrinogen or the other clotting factors. WEB: http://en.wikipedia.org/wiki/Blood_plasma PMID: 18229666.Adv Med Sci. 2007;52 Suppl 1:204-6.Antioxidant activity of blood serum and saliva in patients with periodontal disease treated due to epilepsy. PERSON: Maura Gasparetto|PERSON: Melanie Courtot|PERSON: Philippe Rocca-Serra subclass blood plasma specimen (('filtration' or 'centrifugation' or 'dialysis') and ('has specified input' some 'blood specimen')) OBI:0100067 bronchial alveolar lavage bronchial alveolar lavage metadata complete BAL Group of biomaterials present in the bronchial aveolar space of an organism which are collected through lavage including the reagents used to for the lavage process, organisms, cells, and cellular secretions present in the bronchial aveolar space. GROUP: IEDB solution containing lung derived T cells, eosinophils, and TNFa. PERSON: Bjoern Peters equivalent lavage fluid specimen lavage lung -OBI:0302716 pool of specimens pool of specimens metadata complete A pool of specimens is a mixture of a population of samples which have been gathered from one or more sample populations, obtained by the physical process of mixing individual specimens, e.g. mixing the DNA collected from the individual fish. GROUP: CEBS PERSON: Jennifer Fostel check with advisors as to how to represent multiple instances of any class? a set of specimens which have been gathered from one or more sample_populations, obtained by the physical process of mixing individual specimens, e.g. mixing the DNA collected from the individual fish equivalent specimen ('material combination' and ('has_specified_input' only 'specimen')) +OBI:0302716 pool of specimens pool of specimens metadata complete A pool of specimens is a mixture of a population of samples which have been gathered from one or more sample populations, obtained by the physical process of mixing individual specimens, e.g. mixing the DNA collected from the individual fish. GROUP: CEBS PERSON: Jennifer Fostel check with advisors as to how to represent multiple instances of any class? a set of specimens which have been gathered from one or more sample_populations, obtained by the physical process of mixing individual specimens, e.g. mixing the DNA collected from the individual fish equivalent specimen ('material combination' and ('has specified input' only 'specimen')) OBI:1000049 whole mount tissue whole mount tissue metadata complete whole mount sample A whole organism preparation resulting from a histological preparation known as whole mount preparation where the whole specimen is mounted or spread on the microscope (glass) slide GROUP: OBI PERSON: Helen Parkinson|PERSON: Philippe Rocca-Serra PRS:22-02-2008: indicates the need to create a protocol application and distinguish it from this entity|PRS:22-02-2008: is a material which has output_role during whole mount preparation protocol-application subclass whole organism preparation histological sample preparation 'derives from' some 'material anatomical entity' -OBI:1110041 lymph node cell specimen lymph node cell specimen metadata incomplete A cell specimen comprised of a mixed population of cells obtained by processing whole lymph node into individual cells, typically performed using a sieve. This population includes T cells, B cells, macrophages, and other cell types. IEDB IEDB equivalent cell specimen ('organ harvesting' and ('has_specified_input' some 'lymph node')) -OBI:1110116 splenocyte specimen splenocyte specimen metadata complete A cell specimen comprised of a mixed cell population obtained by processing whole spleen into individual cells, typically performed using a sieve or blender. This population includes T cells, B cells, macrophages, and other cell types. IEDB IEDB equivalent cell specimen ('organ harvesting' and ('has_specified_input' some 'spleen')) +OBI:1110041 lymph node cell specimen lymph node cell specimen metadata incomplete A cell specimen comprised of a mixed population of cells obtained by processing whole lymph node into individual cells, typically performed using a sieve. This population includes T cells, B cells, macrophages, and other cell types. IEDB IEDB equivalent cell specimen ('organ harvesting' and ('has specified input' some 'lymph node')) +OBI:1110116 splenocyte specimen splenocyte specimen metadata complete A cell specimen comprised of a mixed cell population obtained by processing whole spleen into individual cells, typically performed using a sieve or blender. This population includes T cells, B cells, macrophages, and other cell types. IEDB IEDB equivalent cell specimen ('organ harvesting' and ('has specified input' some 'spleen')) OBI:1200000 FFPE specimen FFPE specimen formalin-fixed paraffin-embeded specimen A specimen that has been fixed in formalin and embedded in paraffin. https://www.biochain.com/general/what-is-ffpe-tissue/ Many of today’s researchers prefer to use Formalin-Fixed Paraffin-Embedded samples of tissues for their IHC, histological or in-situ genomic analyses. Professionally fixed and embedded FFPE samples and the biomolecules they contain are reasonably stable at ambient temperatures. -based on https://lab-ally.com/histopathology-resources/ffpe-samples/ MIABIS https://github.com/obi-ontology/obi/issues/1019 subclass paraffin specimen OBI:2000000 uterine cervix specimen A specimen that is derived from some uterine cervix Mark A. Miller ORCID:0000-0001-9076-6066|Christian Stoeckert ORCID:0000-0002-5714-991X Mark A. Miller ORCID:0000-0001-9076-6066|Christian Stoeckert ORCID:0000-0002-5714-991X equivalent specimen from organism collecting specimen from organism (tissue and ('part of' some 'uterine cervix')) UBERON_0000002 OBI:2000001 urethra specimen A specimen that is derived from some urethra Mark A. Miller ORCID:0000-0001-9076-6066|Christian Stoeckert ORCID:0000-0002-5714-991X Mark A. Miller ORCID:0000-0001-9076-6066|Christian Stoeckert ORCID:0000-0002-5714-991X equivalent specimen from organism collecting specimen from organism (tissue and ('part of' some urethra)) UBERON_0000057 diff --git a/src/ontology/templates/study-designs.tsv b/src/ontology/templates/study-designs.tsv index 50ae1a83..a3a15ad3 100644 --- a/src/ontology/templates/study-designs.tsv +++ b/src/ontology/templates/study-designs.tsv @@ -34,7 +34,7 @@ OBI:0001337 clinical history design clinical history design metadata complete A OBI:0001358 post-transcriptional modification design post-transcriptional modification design metadata complete A study design in which a modification of the transcriptome, proteome (not genome) is made, for example RNAi, antibody targeting. MO_392 cellular_modification_design Person: Chris Stoeckert, Jie Zheng post transcription modification design? or more clear RNAi design / antibody targeting design? need to check the use cases subclass intervention design biological feature identification objective study intervention OBI:0001365 cellular process design cellular process design metadata complete A study design that aims to study the processes that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. MO_810 cellular_process_design Person: Chris Stoeckert, Jie Zheng subclass study design ('cellular feature identification objective' and ('is about' some 'cellular process')) OBI:0001374 injury design injury design metadata complete A study design in which the response of an organism(s) to injury or damage is studied. MO_726 injury_design Person: Chris Stoeckert, Jie Zheng subclass study design organism feature identification objective -OBI:0001377 organism status comparison design organism status comparison design metadata complete A study design that compares samples from live and dead organisms. MO_841 organism_status_design Person: Chris Stoeckert, Jie Zheng subclass study design biological feature identification objective ('is concretized as' some ('realized in' some (assay and (has_specified_input some ('pre-mortem specimen' or 'post mortem specimen'))))) +OBI:0001377 organism status comparison design organism status comparison design metadata complete A study design that compares samples from live and dead organisms. MO_841 organism_status_design Person: Chris Stoeckert, Jie Zheng subclass study design biological feature identification objective ('is concretized as' some ('realized in' some (assay and ('has specified input' some ('pre-mortem specimen' or 'post mortem specimen'))))) OBI:0001387 genotyping by array design genotyping by array design metadata complete A study design that classifies an individual or group of individuals on the basis of alleles, haplotypes, SNPs using microarray technology. MO_560 genotyping_design Person: Chris Stoeckert, Jie Zheng subclass genotyping design OBI:0001396 stimulus or stress design stimulus or stress design metadata complete A study design in which the response of an organism(s) to the stress or stimulus is studied, e.g. osmotic stress, heat shock, radiation exposure, behavioral treatment etc. MO_568 stimulus_or_stress_design Person: Chris Stoeckert, Jie Zheng subclass intervention design ('organism feature identification objective' and ('is about' some 'response to stimulus')) study intervention OBI:0001401 protocol optimization design protocol optimization design metadata complete A study design where different protocols or protocol parameters are compared aims to find an optimized protocol MO_934 optimization_design Person: Chris Stoeckert, Jie Zheng subclass study design protocol optimization objective From 3197d0d461ab403d8dce112458f457770de9c279 Mon Sep 17 00:00:00 2001 From: Sebastian Duesing <66700705+sebastianduesing@users.noreply.github.com> Date: Fri, 22 Nov 2024 13:26:02 -0600 Subject: [PATCH 04/12] Replace alternative term with alternative label in all templates --- src/ontology/templates/administration.tsv | 4 ++-- src/ontology/templates/antibody-purification.tsv | 4 ++-- src/ontology/templates/assays.tsv | 4 ++-- src/ontology/templates/biopsy.tsv | 4 ++-- src/ontology/templates/data-sets.tsv | 4 ++-- src/ontology/templates/data-transformations.tsv | 4 ++-- src/ontology/templates/devices.tsv | 4 ++-- src/ontology/templates/epitope-assays.tsv | 4 ++-- src/ontology/templates/medical-history.tsv | 4 ++-- src/ontology/templates/obsolete.tsv | 4 ++-- src/ontology/templates/organizations.tsv | 4 ++-- src/ontology/templates/physical-examination.tsv | 4 ++-- src/ontology/templates/sample-collection.tsv | 4 ++-- src/ontology/templates/sequence-analysis.tsv | 4 ++-- src/ontology/templates/specimen-assay-data.tsv | 4 ++-- src/ontology/templates/specimens.tsv | 4 ++-- src/ontology/templates/study-designs.tsv | 4 ++-- src/ontology/templates/value-specifications.tsv | 4 ++-- 18 files changed, 36 insertions(+), 36 deletions(-) diff --git a/src/ontology/templates/administration.tsv b/src/ontology/templates/administration.tsv index 591c8efe..c0f26942 100644 --- a/src/ontology/templates/administration.tsv +++ b/src/ontology/templates/administration.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type logical note parent class target of administration material administered administration technique objective associated axiom -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'realizes' some ('target of material addition role' and ('role of' some %)) SPLIT=| C 'realizes' some ('material to be added role' and ('role of' some %)) SPLIT=| C 'has part' some % SPLIT=| C achieves_planned_objective some % C % +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type logical note parent class target of administration material administered administration technique objective associated axiom +ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'realizes' some ('target of material addition role' and ('role of' some %)) SPLIT=| C 'realizes' some ('material to be added role' and ('role of' some %)) SPLIT=| C 'has part' some % SPLIT=| C achieves_planned_objective some % C % OBI:0000281 intraperitoneal injection intraperitoneal injection is the injection of a material entity (bearing the administered substance role) into the peritoneum (bearing the target role) of an organism using a syringe BP equivalent intraperitoneal administration ('realizes' some ('function' and ('inheres in' some 'syringe'))) OBI:0000429 intraperitoneal administration intraperitoneal administration The administration of a substance into the peritoneum of an organism Rats were injected intraperitoneally with either rrIL-6 (250 ng/0.5 ml) or equal-volume sterile saline twice within an interval of 24 h Person:Bjoern Peters equivalent administering substance in vivo peritoneum OBI:0000837 oral ingestion of pill oral ingestion of pill An adding a material entity to target with the entity is a pill and the target is the mouth Person:Alan Ruttenberg 2009/09/28 Alan Ruttenberg. Fucoidan-use-case equivalent oral administration pill ('has specified input' some 'pill') diff --git a/src/ontology/templates/antibody-purification.tsv b/src/ontology/templates/antibody-purification.tsv index 955a911e..1279f84b 100644 --- a/src/ontology/templates/antibody-purification.tsv +++ b/src/ontology/templates/antibody-purification.tsv @@ -1,5 +1,5 @@ -id rdfs label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent output -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester SPLIT=| A term tracker item SPLIT=| CLASS_TYPE C % C 'has specified output' some % +id rdfs label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent output +ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester SPLIT=| A term tracker item SPLIT=| CLASS_TYPE C % C 'has specified output' some % OBI:0003616 antibody purification of MHC class I protein complex An antibody purification of MHC protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of MHC class I protein complex, while others contain impurities and are not of interest. Randi Vita Randi Vita|Sebastian Duesing equivalent antibody purification of MHC protein complex MHC class I protein complex OBI:0003617 antibody purification of human MHC class I protein complex An antibody purification of MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of human MHC class I protein complex, while others contain impurities and are not of interest. Randi Vita Randi Vita|Sebastian Duesing equivalent antibody purification of MHC class I protein complex human MHC class I protein complex OBI:0003618 antibody purification of HLA protein complex with A2 serotype An antibody purification of human MHC class I protein complex to separate a material entity into different compositions of which one fraction contains a higher concentration of HLA protein complex with A2 serotype, while others contain impurities and are not of interest. Randi Vita Randi Vita|Sebastian Duesing equivalent antibody purification of human MHC class I protein complex HLA protein complex with A2 serotype diff --git a/src/ontology/templates/assays.tsv b/src/ontology/templates/assays.tsv index 3bf66f7c..066cfd1e 100644 --- a/src/ontology/templates/assays.tsv +++ b/src/ontology/templates/assays.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type logical note parent class material processing technique detection technique evaluant measurand analyte device reagent molecular label input output target entity target context objective associated axioms -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some (% and 'has role' some 'evaluant role')) and (realizes some ('evaluant role' and ('role of' some %))) SPLIT=| C ('has specified input' some %) and (realizes some ('measurand role' and ('inheres in' some %))) C ('has specified input' some %) and (realizes some ('analyte role' and ('inheres in' some %))) C ('has specified input' some %) and (realizes some (function and ('inheres in' some %))) SPLIT=| C ('has specified input' some %) and (realizes some ('reagent role' and ('inheres in' some %))) C ('has specified input' some %) and (realizes some ('molecular label role' and ('inheres in' some %))) C 'has specified input' some % C 'has specified output' some % C 'has specified output' some ('is about' some %) C 'has specified output' some ('is about' some ( 'has assay target context' some %)) C achieves_planned_objective some % C % +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type logical note parent class material processing technique detection technique evaluant measurand analyte device reagent molecular label input output target entity target context objective associated axioms +ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some (% and 'has role' some 'evaluant role')) and (realizes some ('evaluant role' and ('role of' some %))) SPLIT=| C ('has specified input' some %) and (realizes some ('measurand role' and ('inheres in' some %))) C ('has specified input' some %) and (realizes some ('analyte role' and ('inheres in' some %))) C ('has specified input' some %) and (realizes some (function and ('inheres in' some %))) SPLIT=| C ('has specified input' some %) and (realizes some ('reagent role' and ('inheres in' some %))) C ('has specified input' some %) and (realizes some ('molecular label role' and ('inheres in' some %))) C 'has specified input' some % C 'has specified output' some % C 'has specified output' some ('is about' some %) C 'has specified output' some ('is about' some ( 'has assay target context' some %)) C achieves_planned_objective some % C % CHMO:0000087 fluorescence microscopy assay fluorescence imaging|fluorescence microscopic imaging|FM Any type of light microscopy assay where the specimen can be made to fluoresce (emit energy as visible light) by illuminating it with light of specific wavelengths. These specimens are called fluorophores. CHMO subclass light microscopy assay ('material entity' and ('bearer of' some fluorescence)) CHMO:0000089 confocal fluorescence microscopy assay CLSM|confocal fluorescence imaging|confocal laser scanning fluorescence microscopy|confocal laser scanning microscopy|confocal-laser scanning microscopy|fluorescence confocal microscopy|fluorescence confocal scanning laser microscopy|LSCM|scanning confocal fluorescence microscopy Microscopy where the specimen can be made to fluoresce (emit energy as visible light) by scanning a gas (Ar or Kr) laser spot of specific wavelength over its surface and using a spatial pinhole to eliminate out-of-focus fluorescence. CHMO subclass microscopy assay CHMO:0000102 light microscopy assay light microscopy|OM|optical microscopy Microscopy where the specimen is illuminated with visible light and a system of lenses is used to produce an image. CHMO subclass microscopy assay diff --git a/src/ontology/templates/biopsy.tsv b/src/ontology/templates/biopsy.tsv index 7a4d70c3..9d1c616a 100644 --- a/src/ontology/templates/biopsy.tsv +++ b/src/ontology/templates/biopsy.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class material anatomical entity input device output entity -ID LABEL A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE CI C 'has specified input' some % C 'has specified input' some % C 'has specified output' some % +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class material anatomical entity input device output entity +ID LABEL A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE CI C 'has specified input' some % C 'has specified input' some % C 'has specified output' some % OBI:0002650 biopsy ready for release A specimen collection that obtains a sample of tissue or cell from a living multicellular organism body for diagnostic purposes by means intended to be minimally invasive. https://en.wikipedia.org/wiki/Biopsy Biopsy of a potentially cancerous mole. Nicole Vasilevsky|Damion Dooley subclass collecting specimen from organism material anatomical entity device pre-mortem specimen OBI:0002651 image guided biopsy ready for release image-guided biopsy|imaging guided biopsy|image guided needle biopsy A biopsy which uses an imaging procedure to guide a needle biopsy. https://www.mayoclinic.org/diseases-conditions/cancer/in-depth/biopsy/art-20043922 Image-guided needle biopsy allows a doctor to biopsy suspicious areas that aren't readily seen or felt through skin, such as in a prostate gland. Damion Dooley subclass needle biopsy OBI:0002652 computed tomography assisted biopsy ready for release Computed Tomography Assisted Biopsy|CT Guided Biopsy|CT Assisted Biopsy|Computed Tomography-Guided Needle Biopsy A needle biopsy guided by real-time computed tomography (CT) scan images. http://purl.obolibrary.org/obo/NCIT_C137909 A CT Guided Biopsy is a procedure performed by a radiologist to obtain a small tissue sample through a needle. Damion Dooley subclass image guided biopsy computed tomography scanner diff --git a/src/ontology/templates/data-sets.tsv b/src/ontology/templates/data-sets.tsv index 57de9134..749d1489 100644 --- a/src/ontology/templates/data-sets.tsv +++ b/src/ontology/templates/data-sets.tsv @@ -1,5 +1,5 @@ -ontology ID label has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class is about is specified output of has member -ID A rdfs:label AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=, A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE CI C 'is about' some % C 'is specified output of' some % C 'has member' some % +ontology ID label has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class is about is specified output of has member +ID A rdfs:label AI has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=, A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE CI C 'is about' some % C 'is specified output of' some % C 'has member' some % OBI:0003327 image data set A data set that is comprised of multidimensional structured measurements and metadata required for a morphological representation of an entity. An image data set can be the source from which an image (such as a 2D image using pixels or a 3D image using voxels) is produced. The output produced by a digital imaging technique, such as microscopy, MRI, or CT. https://orcid.org/0000-0001-9625-1899 ""William D. Duncan"",https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie"",https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik"",https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl"",https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra"",https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"" https://github.com/obi-ontology/obi/issues/1481 subclass data set entity OBI:0003328 magnetic resonance image data set An image data set whose information content originates from some MR imaging assay and is about some MRI participant. MRI at a Glance, ISBN 10: 1119053552 The DICOM file produced by an MRI machine when a multiple sclerosis patient undergoes a brain scan. https://orcid.org/0000-0001-9625-1899 ""William D. Duncan"",https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie"",https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik"",https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl"",https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra"",https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"" https://github.com/obi-ontology/obi/issues/1481 equivalent image data set magnetic resonance imaging participant OBI:0003331 raw image data set An image data set that encodes measurement values produced by some instrument before undergoing a data transformation. The untransformed (""k-space"") data produced by an MRI machine, prior to mathematical transformation into a form that corresponds to the anatomical structure of the brain. https://orcid.org/0000-0001-9625-1899 ""William D. Duncan"",https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie"",https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik"",https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl"",https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra"",https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"",https://orcid.org/0000-0002-1604-3078 ""Alan Ruttenberg"" https://github.com/obi-ontology/obi/issues/1481 subclass image data set diff --git a/src/ontology/templates/data-transformations.tsv b/src/ontology/templates/data-transformations.tsv index 36179101..e9b522b1 100644 --- a/src/ontology/templates/data-transformations.tsv +++ b/src/ontology/templates/data-transformations.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note term tracker item logical type parent class input output objective associated axioms -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A term tracker item CLASS_TYPE C % C 'has specified input' some % C 'has specified output' some % C achieves_planned_objective some % C % +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note term tracker item logical type parent class input output objective associated axioms +ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A term tracker item CLASS_TYPE C % C 'has specified input' some % C 'has specified output' some % C achieves_planned_objective some % C % OBI:0003355 image data set analysis The process of deriving a data item from an image data set using computer algorithms. The produced data item can be an image data set, data measurement, or any other data item. https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik""|https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl""|https://orcid.org/0000-0001-9625-1899 ""William D. Duncan""|https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra""|https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie""|https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"" https://github.com/obi-ontology/obi/issues/1481 subclass data transformation image data set OBI:0003356 raw magnetic resonance image data set reconstruction A process that transforms raw magnetic resonance image data from an NMR/MRI machine into a reconstructed magnetic resonance image data set. A Fourier transform of raw ""k-space"" data produced into an image data set that represents the anatomical structure of the tissue examined. https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik""|https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl""|https://orcid.org/0000-0001-9625-1899 ""William D. Duncan""|https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra""|https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie""|https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"" https://github.com/obi-ontology/obi/issues/1481 equivalent image data set analysis raw magnetic resonance image data set reconstructed magnetic resonance image data set OBI:0003647 tandem mass spectrometry analysis tandem mass spectrometry analysis A mass spectrometry analysis in which the data being analyzed is the result of a tandem mass spectrometry assay. Sebastian Duesing https://github.com/obi-ontology/obi/issues/1684 equivalent mass spectrometry analysis ('data item' and 'is specified output of' some 'tandem mass spectrometry assay') diff --git a/src/ontology/templates/devices.tsv b/src/ontology/templates/devices.tsv index fb369a0e..32bce389 100644 --- a/src/ontology/templates/devices.tsv +++ b/src/ontology/templates/devices.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class function has part part of manufactured by associated axioms -ID LABEL A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has function' some % SPLIT=| C 'has part' some % SPLIT=| C 'part of' some % C is_manufactured_by value % C % SPLIT=| +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class function has part part of manufactured by associated axioms +ID LABEL A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has function' some % SPLIT=| C 'has part' some % SPLIT=| C 'part of' some % C is_manufactured_by value % C % SPLIT=| OBI:0000038 chromatography column chromatography column metadata incomplete Chromatography column in chemistry is a tube and contents (typically glass) used to purify individual chemical compounds from mixtures of compounds. It is often used for preparative applications on scales from micrograms up to kilograms. http://en.wikipedia.org/wiki/Column_chromatography Frank Gibson open tracker https://sourceforge.net/tracker/index.php?func=detail&aid=2881353&group_id=177891&atid=886178 device ('material separation function' and ('realized in' only 'preparative chromatography')) container OBI:0000041 pump valve switch pump valve switch metadata incomplete A pump valve switch is a cardinal part of a liquid chromatography instrument that controls the flow. OBI OBI Instrument branch FG:I would assume this should be a pump valve control switch and it would not be specific to a liquid chromatography instrument device mechanical function OBI:0000048 chromatography device chromatography device metadata complete chromatography instrument A device that facilitates the separation of mixtures. The function of a chromatography device involves passing a mixture dissolved in a ""mobile phase"" through a stationary phase, which separates the analyte to be measured from other molecules in the mixture and allows it to be isolated. http://en.wikipedia.org/wiki/Chromatography Frank Gibson open tracker https://sourceforge.net/tracker/index.php?func=detail&aid=2881353&group_id=177891&atid=886178 device contain function|environment control function|measure function|material separation function diff --git a/src/ontology/templates/epitope-assays.tsv b/src/ontology/templates/epitope-assays.tsv index 7e7bc676..d1e7e6d6 100644 --- a/src/ontology/templates/epitope-assays.tsv +++ b/src/ontology/templates/epitope-assays.tsv @@ -1,5 +1,5 @@ -Ontology ID label editor preferred term has curation status alternative term IEDB alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class material processing technique detection technique reagent input output MHC source target entity target context unit -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| A IEDB alternative term AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some %) and (realizes some ('reagent role' and ('inheres in' some %))) C 'has specified input' some % C 'has specified output' some % C 'has specified input' some (% and ('has part' some 'MHC protein complex')) C 'has specified output' some ('is about' some %) C 'has specified output' some ('is about' some ( 'has assay target context' some %)) C 'has specified output' some ('has measurement unit label' value %) +Ontology ID label editor preferred term has curation status alternative label IEDB alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class material processing technique detection technique reagent input output MHC source target entity target context unit +ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| A IEDB alternative term AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some %) and (realizes some ('reagent role' and ('inheres in' some %))) C 'has specified input' some % C 'has specified output' some % C 'has specified input' some (% and ('has part' some 'MHC protein complex')) C 'has specified output' some ('is about' some %) C 'has specified output' some ('is about' some ( 'has assay target context' some %)) C 'has specified output' some ('has measurement unit label' value %) OBI:0001194 ELISPOT assay measuring epitope specific transforming growth factor-beta production by T cells TGFb release|ELISPOT An enzyme-linked immunospot assay that detects transforming growth factor-beta production by T cells. IEDB PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters equivalent enzyme-linked immunospot assay ('transforming growth factor beta production' and ('process is result of' some 'MHC:epitope complex binding to TCR')) OBI:0001196 cytometric bead array assay measuring epitope specific IP-10 production by T cells CXCL10/IP-10 release|cytometric bead array A cytometric bead array assay that detects IP-10 production by T cells. IEDB PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters equivalent antigen detection by cytometric bead array assay ('IP-10 production' and ('process is result of' some 'MHC:epitope complex binding to TCR')) OBI:0001198 assay measuring epitope specific interleukin-27 production by T cells IL-27 release|biological activity A T cell epitope specific cytokine production assay that detects interleukin-27 production by T cells. IEDB PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters equivalent assay ('interleukin-27 production' and ('process is result of' some 'MHC:epitope complex binding to TCR')) diff --git a/src/ontology/templates/medical-history.tsv b/src/ontology/templates/medical-history.tsv index 3dafc77d..c1ccb4d3 100644 --- a/src/ontology/templates/medical-history.tsv +++ b/src/ontology/templates/medical-history.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class +ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % OBI:0002368 clinical history of cancer A clinical history in which there is a diagnosis of cancer. NCI BBRB, OBIB Chris Stoeckert, Helena Ellis NCI BBRB subclass clinical history OBI:0002369 clinical history devoid of cancer clinical history of no cancer A clinical history in which there was no diagnosis of cancer. NCI BBRB, OBIB Chris Stoeckert, Helena Ellis NCI BBRB subclass clinical history OBI:0002370 unknown clinical history of cancer A clinical history in which it is not known whether there was a diagnosis of cancer. NCI BBRB, OBIB Chris Stoeckert, Helena Ellis NCI BBRB subclass clinical history diff --git a/src/ontology/templates/obsolete.tsv b/src/ontology/templates/obsolete.tsv index 39f14605..fdaba18a 100755 --- a/src/ontology/templates/obsolete.tsv +++ b/src/ontology/templates/obsolete.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term IEDB Alternative Terms definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class obsolete obsolescence reason replacement term Randi notes on obsolescence -ID LABEL A editor preferred term AI has curation status A alternative term SPLIT=| A IEDB alternative term AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % AT deprecated^^xsd:boolean AI has obsolescence reason AI term replaced by +ontology ID label editor preferred term has curation status alternative label IEDB Alternative Terms definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class obsolete obsolescence reason replacement term Randi notes on obsolescence +ID LABEL A editor preferred term AI has curation status A alternative label SPLIT=| A IEDB alternative term AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % AT deprecated^^xsd:boolean AI has obsolescence reason AI term replaced by OBI:0000050 obsolete_platform metadata incomplete A platform is an object_aggregate that is the set of instruments and software needed to perform a process. definition_source: OBI. OBI Instrument branch OBI Instrument branch subclass Obsolete Class true IAO:0000103 OBI:0000100 obsolete_role of being first subject treated metadata complete First subject treated role is a study subject role borne by the subject realized in the application of the process specified in intervention study design with no previous study subject realizing the role prior in the study OBI Rat 1A; first enrolled patient to receive treatment Role Branch subclass Obsolete Class true IAO:0000103 OBI:0000109 obsolete biological vector role metadata complete a biological vector role is a material to be added role that is realized by the process of transmitting material to the organism that is the target of the transmission. OBI and Wikipedia 1983 Sci. Amer. Jan. 58/2 Plasmids are routinely used as vectors for introducing foreign DNA into bacteria.|Some epidemiological aspects and vector role of tick infestation on layers in the Faisalabad district (Pakistan). http://journals.cambridge.org/action/displayAbstract;jsessionid=0373164489D00868AEEF2C556EB4FD29.tomcat1?fromPage=online&aid=624280 GROUP: Role Branch subclass Obsolete Class true IAO:0000103 diff --git a/src/ontology/templates/organizations.tsv b/src/ontology/templates/organizations.tsv index dd3c57c6..17735113 100644 --- a/src/ontology/templates/organizations.tsv +++ b/src/ontology/templates/organizations.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type type -ID LABEL A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE TYPE SPLIT=| +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type type +ID LABEL A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE TYPE SPLIT=| OBI:0000462 Affymetrix Affymetrix An organization which supplies technology, tools and protocols for use in high throughput applications Affymetrix supplied microarray manufacturer|material supplier OBI:0000752 Thermo Thermo Philippe Rocca-Serra manufacturer OBI:0000753 Waters Waters Philippe Rocca-Serra manufacturer diff --git a/src/ontology/templates/physical-examination.tsv b/src/ontology/templates/physical-examination.tsv index ea2ebf3f..ede2326d 100644 --- a/src/ontology/templates/physical-examination.tsv +++ b/src/ontology/templates/physical-examination.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type logical note parent class detection technique evaluant device input output anatomical site assessed biological trait -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some (% and 'has role' some 'evaluant role')) and (realizes some ('evaluant role' and ('role of' some %))) SPLIT=| C ('has specified input' some %) and (realizes some (function and ('inheres in' some %))) SPLIT=| C 'has specified input' some % C 'has specified output' some % C 'has specified output' some ('is about' some %) C 'has specified output' some ('is quality measurement of' some %) +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type logical note parent class detection technique evaluant device input output anatomical site assessed biological trait +ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some (% and 'has role' some 'evaluant role')) and (realizes some ('evaluant role' and ('role of' some %))) SPLIT=| C ('has specified input' some %) and (realizes some (function and ('inheres in' some %))) SPLIT=| C 'has specified input' some % C 'has specified output' some % C 'has specified output' some ('is about' some %) C 'has specified output' some ('is quality measurement of' some %) OBI:0003501 functional assessment of individual A physical examination of an organism's ability to perform functional activities. Critical Path Institute Daniel Olson, ORCID: 0000-0002-8134-1207 https://github.com/obi-ontology/obi/issues/1637 subclass physical examination of an organism OBI:0003502 facial atrophy assessment An observational assessment of the loss of facial muscle tissue due to inactivity or disease. Critical Path Institute Daniel Olson, ORCID: 0000-0002-8134-1207 https://github.com/obi-ontology/obi/issues/1637 subclass observational assessment of individual facial muscle facial muscle performance OBI:0003503 tongue atrophy assessment An observational assessment of the loss of muscle tissue related to tongue movement due to inactivity or disease. Critical Path Institute Daniel Olson, ORCID: 0000-0002-8134-1207 https://github.com/obi-ontology/obi/issues/1637 subclass observational assessment of individual tongue facial muscle performance diff --git a/src/ontology/templates/sample-collection.tsv b/src/ontology/templates/sample-collection.tsv index 34df2de5..834b94a1 100644 --- a/src/ontology/templates/sample-collection.tsv +++ b/src/ontology/templates/sample-collection.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class specimen type -ID LABEL A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has specified output' some (% and 'has role' some 'specimen role') +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class specimen type +ID LABEL A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has specified output' some (% and 'has role' some 'specimen role') OBI:0002904 adult arthropod specimen collection process collection of adults A live arthropod specimen collection process in which the arthropods are in the adult stage. MIRO:30000052 John Judkins https://github.com/obi-ontology/obi/issues/1217 live arthropod specimen collection process OBI:0002905 animal-biting arthropod specimen collection by aspiration animal biting catch An arthropod specimen collection by aspiration that occurs while the arthropod is biting an animal. MIRO:30000012 John Judkins https://github.com/obi-ontology/obi/issues/1217 arthropod specimen collection by aspiration OBI:0002906 animal-biting outdoor arthropod specimen collection by aspiration animal biting catch - outdoors An animal-biting arthropod specimen collection by aspiration that occurs outside a building. MIRO:30000014 John Judkins https://github.com/obi-ontology/obi/issues/1217 animal-biting arthropod specimen collection by aspiration diff --git a/src/ontology/templates/sequence-analysis.tsv b/src/ontology/templates/sequence-analysis.tsv index 09ce802a..8b4ce88c 100644 --- a/src/ontology/templates/sequence-analysis.tsv +++ b/src/ontology/templates/sequence-analysis.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class output input input of output of objective -ID A rdfs:label A editor preferred term AL has curation status A alternative term SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has specified output' some % C 'has specified input' some % C 'is specified input of' some % C 'is specified output of' some % C achieves_planned_objective some % +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class output input input of output of objective +ID A rdfs:label A editor preferred term AL has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has specified output' some % C 'has specified input' some % C 'is specified input of' some % C 'is specified output of' some % C achieves_planned_objective some % OBI:0002565 adapter-sequence trimming A data transformation in which adapter sequences at the end of a molecular sequence are cut (removed). Dan Berrios Dan Berrios subclass sequence trimming adapter-trimmed sequence data 'adapter sequence data' OBI:0002566 file merge A data transformation in which data contained in 2 or more files are merged into a single file. Dan Berrios Dan Berrios subclass data transformation OBI:0002567 sequence alignment A data transformation in which one or more sequences (reads) are positioned on a reference sequence template (often a reference set of genes), according to the genetic base-pairing paradigm. Dan Berrios Dan Berrios subclass sequence analysis data transformation aligned sequence data sequence data diff --git a/src/ontology/templates/specimen-assay-data.tsv b/src/ontology/templates/specimen-assay-data.tsv index 6bb77a2c..452c6861 100644 --- a/src/ontology/templates/specimen-assay-data.tsv +++ b/src/ontology/templates/specimen-assay-data.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item axiom -ID LABEL A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item EC % +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item axiom +ID LABEL A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item EC % OBI:0003243 blood assay datum A data item that is the specified output of a blood assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and 'is specified output of' some 'blood assay') OBI:0003244 blood microbiology datum An organism detection datum that is the specified output of a blood microbiology assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('organism detection datum' and 'is specified output of' some 'blood microbiology assay') OBI:0003245 feces assay datum A data item that is the specified output of a feces assay. VEuPathDB John Judkins https://github.com/obi-ontology/obi/issues/1428 ('data item' and 'is specified output of' some 'feces assay') diff --git a/src/ontology/templates/specimens.tsv b/src/ontology/templates/specimens.tsv index 934e7a7d..2ea0f976 100644 --- a/src/ontology/templates/specimens.tsv +++ b/src/ontology/templates/specimens.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class specimen collection process gross anatomical part collection process input associated axioms URI -ID A rdfs:label A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'is specified output of' some % C ('is specified output of' some 'specimen collection process') and ('derives from' some %) C 'is specified output of' some ('specimen collection process' and 'has specified input' some %) C % SPLIT=| +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class specimen collection process gross anatomical part collection process input associated axioms URI +ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'is specified output of' some % C ('is specified output of' some 'specimen collection process') and ('derives from' some %) C 'is specified output of' some ('specimen collection process' and 'has specified input' some %) C % SPLIT=| OBI:0000651 urine specimen urine specimen metadata complete a portion of urine collected from an organism This could be instead a kind of collection of secreted stuff. Among secreted stuff there is passive, and active. urine is secreted, passiv. lavage is secreted, active|are we happy calling collection of urine a material separation?|4/10/2011BP: It seems to me that the editor notes refer to a previous version, and are no longer relevant. equivalent specimen from organism collecting specimen from organism urine OBI:0000655 blood specimen blood specimen ready for release a material entity derived from a portion of blood collected from an organism Bjoern Peters blood drawn from a human for glucose assay Bjoern Peters equivalent specimen from organism collecting specimen from organism blood OBI:0000671 sample from organism sample from organism example to be eventually removed a material obtained from an organism in order to be a representative of the whole we need to work on this: Is taking a urine sample a material separation process? If not, we will need to specify what 'taking a sample from organism' entails. We can argue that the objective to obtain a urine sample from a patient is enough to call it a material separation process, but it could dilute what material separation was supposed to be about.|5/29: This is a helper class for now equivalent specimen from organism 'has role' some 'material sample role' diff --git a/src/ontology/templates/study-designs.tsv b/src/ontology/templates/study-designs.tsv index a3a15ad3..f56b5ab2 100644 --- a/src/ontology/templates/study-designs.tsv +++ b/src/ontology/templates/study-designs.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class objective independent variable dependent variable assay associated superclasses associated equivalent classes -ID LABEL A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ('study design independent variable' and ('is about' some %)) SPLIT=| C 'has part' some ('study design dependent variable' and ('is about' some %)) SPLIT=| C 'is concretized as' some ('realized in' some ('has part' some %)) SPLIT=| SC % SPLIT=| EC % SPLIT=| +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class objective independent variable dependent variable assay associated superclasses associated equivalent classes +ID LABEL A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ('study design independent variable' and ('is about' some %)) SPLIT=| C 'has part' some ('study design dependent variable' and ('is about' some %)) SPLIT=| C 'is concretized as' some ('realized in' some ('has part' some %)) SPLIT=| SC % SPLIT=| EC % SPLIT=| OBI:0000115 intervention design intervention design pending final vetting An intervention design is a study design in which a controlled process applied to the subjects (the intervention) serves as the independent variable manipulated by the experimentalist. The treatment (perturbation or intervention) defined can be defined as a combination of values taken by independent variable manipulated by the experimentalists are applied to the recruited subjects assigned (possibly by applying specific methods) to treatment groups. The specificity of intervention design is the fact that independent variables are being manipulated and a response of the biological system is evaluated via response variables as monitored by possibly a series of assays. OBI branch derived PMID: 18208636.Br J Nutr. 2008 Jan 22;:1-11.Effect of vitamin D supplementation on bone and vitamin D status among Pakistani immigrants in Denmark: a randomised double-blinded placebo-controlled intervention study. Philppe Rocca-Serra equivalent study design study intervention OBI:0000951 compound treatment design compound treatment design metadata complete an intervention design in which the treatment is the administration of a compound MO_555 compound_treatment_design PERSON: Bjoern Peters This is meant to include all kinds of material administrations, including vaccinations, chemical compounds etc. subclass study design ('study intervention' and 'administration of material to specimen') OBI:0000985 growth condition intervention design growth condition intervention design metadata complete A study design in which the independent variable is the environmental condition in which the specimen is growing MO_588 growth_condition_design PERSON: Bjoern Peters subclass intervention design study intervention|growth environment diff --git a/src/ontology/templates/value-specifications.tsv b/src/ontology/templates/value-specifications.tsv index adeeb7d4..3dd5092a 100644 --- a/src/ontology/templates/value-specifications.tsv +++ b/src/ontology/templates/value-specifications.tsv @@ -1,5 +1,5 @@ -ontology ID label editor preferred term has curation status alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type type parent class -ID LABEL A editor preferred term AI has curation status A alternative term SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE TYPE C % +ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type type parent class +ID LABEL A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE TYPE C % OBI:0002199 reason for lack of data item An information content entity that provides an explanation why a data item is not provided. OBI cannot be assessed, not applicable, unknown Chris Stoeckert, Helena Ellis NCI BBRB subclass information content entity OBI:0002200 cannot be assessed determination cannot be assessed A reason for lack of data item that is the negative output of a determination if assay will provide reliable results. OBI Chris Stoeckert, Helena Ellis NCI BBRB subclass reason for lack of data item OBI:0002201 determination if assay will provide reliable results A planned process that is used to assess whether an assay will provide reliable results based on the conditions or qualities of the inputs, devices, and other participants of the assay. OBI Chris Stoeckert, Helena Ellis NCI BBRB subclass planned process From d0344ec2304e2c4ef8f261b884e4e21d4e491c69 Mon Sep 17 00:00:00 2001 From: Sebastian Duesing <66700705+sebastianduesing@users.noreply.github.com> Date: Thu, 5 Dec 2024 12:54:27 -0600 Subject: [PATCH 05/12] Release Candidate 2024-12-05 --- obi.owl | 3913 +++++++++++++++++++-------------------- views/NIAID-GSC-BRC.owl | 185 +- views/obi-base.owl | 3416 +++++++++++++++------------------- views/obi.obo | 444 ++++- views/obi_core.owl | 124 +- 5 files changed, 3927 insertions(+), 4155 deletions(-) diff --git a/obi.owl b/obi.owl index 6469e90e..bc9dd2b1 100755 --- a/obi.owl +++ b/obi.owl @@ -13,7 +13,7 @@ xmlns:protege="http://protege.stanford.edu/plugins/owl/protege#" xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - + en Ontology for Biomedical Investigations Advisors for this project come from the IFOMIS group, Saarbruecken and from the Co-ODE group in Manchester @@ -80,7 +80,7 @@ http://creativecommons.org/licenses/by/4.0/ Ontology for Biomedical Investigations Please cite the OBI consortium http://purl.obolibrary.org/obo/obi where traditional citation is called for. However it is adequate that individual terms be attributed simply by use of the identifying PURL for the term, in projects that refer to them. - 2024-10-25 + 2024-12-05 @@ -897,6 +897,19 @@ https://sourceforge.net/tracker/?func=detail&aid=3603413&group_id=177891 + + + + A serial number such as "12324X"; a stop sign; a written proper name such as "OBI + An information content entity that is a mark(s) or character(s) used as a conventional representation of another entity. + + + 2024-03-25 + has symbol + + + + @@ -1219,6 +1232,19 @@ https://sourceforge.net/tracker/?func=detail&aid=3603413&group_id=177891 + + + + disease characteristic (MONDO:0021125) has cross-reference (http://www.geneontology.org/formats/oboInOwl#hasDbXref) "NCIT:C41009"^^xsd:string + An annotation property that links an ontology entity or a statement to a prefixed identifier or URI. + + + 2024-03-18 + has cross-reference + + + + @@ -12310,7 +12336,7 @@ editor = PRS specimen role liver section; a portion of a culture of cells; a nemotode or other animal once no longer a subject (generally killed); portion of blood from a patient. - a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation + A role borne by a material entity that is obtained during a specimen collection process and that can be realized by performing measurements or observations on the specimen. 22Jun09. The definition includes whole organisms, and can include a human. The link between specimen role and study subject role has been removed. A specimen taken as part of a case study is not considered to be a population representative, while a specimen taken as representing a population, e.g. person taken from a cohort, blood specimen taken from an animal) would be considered a population representative and would also bear material sample role. Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation. blood taken from animal: animal continues in study, whereas blood has role specimen. @@ -15323,6 +15349,7 @@ Proposal is to obsolete. + @@ -19941,25 +19968,30 @@ Eur J Cancer. 2009 Jan;45(1):74-81. PMID: 19008094 + + + + + + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - - - - - - - urine specimen a portion of urine collected from an organism @@ -20044,25 +20076,30 @@ Eur J Cancer. 2009 Jan;45(1):74-81. PMID: 19008094 + + + + + + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - - - - - - - blood specimen blood drawn from a human for glucose assay @@ -20143,9 +20180,10 @@ Eur J Cancer. 2009 Jan;45(1):74-81. PMID: 19008094 specimen collection process - drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation + drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation, collecting a stone from a site - A planned process with the objective of collecting a specimen. + A planned process with the objective to obtain a material entity for potential use as an input upon which measurements or observations are performed. + Definition updated following discussion on 2024-10-07 OBI dev call. Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation. Philly2013: A specimen collection can have as part a material entity acquisition, such as ordering from a bank. The distinction is that specimen collection necessarily involves the creation of a specimen role. However ordering cell lines cells from ATCC for use in an investigation is NOT a specimen collection, because the cell lines already have a specimen role. Philly2013: The specimen_role for the specimen is created during the specimen collection process. @@ -20456,10 +20494,7 @@ http://sourceforge.net/p/obi/obi-terms/716/ - - - - + @@ -20469,12 +20504,6 @@ http://sourceforge.net/p/obi/obi-terms/716/ - - - - - - sample from organism a material obtained from an organism in order to be a representative of the whole @@ -20601,23 +20630,6 @@ http://sourceforge.net/p/obi/obi-terms/716/ - - - - - - - - - - - - - - - - - @@ -20670,7 +20682,8 @@ http://sourceforge.net/p/obi/obi-terms/716/ specimen collection objective The objective to collect bits of excrement in the rainforest. The objective to obtain a blood sample from a patient. - A objective specification to obtain a material entity for potential use as an input during an investigation. + A objective specification that is fulfilled by obtaining a material entity for potential use as an input upon which measurements or observations are performed. + OBI recommends against subclassing this term in order to avoid further parallel hierarchies between this term and specimen collection process. Bjoern Peters Bjoern Peters specimen collection objective @@ -21896,7 +21909,7 @@ the role 'adjuvant role' inheres in some 'material entity' a - + @@ -22631,7 +22644,7 @@ the role 'adjuvant role' inheres in some 'material entity' a - + @@ -22645,9 +22658,9 @@ the role 'adjuvant role' inheres in some 'material entity' a A material entity that has the material sample role OBI: workshop + sample sample population - - sample + https://github.com/obi-ontology/obi/issues/1013 material sample @@ -23769,7 +23782,7 @@ http://en.wikipedia.org/wiki/Survival_rate - + @@ -24813,6 +24826,7 @@ placeholder + @@ -24898,39 +24912,43 @@ placeholder - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + - pre-mortem specimen material obtained through a liver biopsy from a human patient a specimen that was taken from a live organism Bjoern Peters - MO_705 premortem + MO_705 premortem pre-mortem specimen @@ -25088,8 +25106,7 @@ placeholder Cytoplasmic RNA extraction from mammalian tissues to create cDNA library (Carninci P, Nakamura M, Sato K, Hayashizaki Y, Brownstein MJ. Cytoplasmic RNA extraction from fresh and frozen mammalian tissues. Biotechniques. 2002;33:306–309.) A RNA extract that is the output of a RNA extraction process in which RNA molecules found in the cytoplasm are extracted. - PERSON: Chris Stoeckert - PERSON: Jie Zheng + PERSON:Chris Stoeckert UPenn Group cytoplasmic RNA extract @@ -25520,7 +25537,7 @@ J Nutr. 2010 Feb;140(2):382-91. Epub 2009 Dec 23. total RNA extract - Extraction of total RNA from cells with Qiagen mini RNeasy kit. + Extraction of total RNA from cells with Qiagen mini RNeasy kit A RNA extract that is the output of an extraction process in which total celluar and organelle RNA molecules are isolated from a specimen. PERSON: Chris Stoeckert @@ -25617,30 +25634,35 @@ J Nutr. 2010 Feb;140(2):382-91. Epub 2009 Dec 23. - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + post mortem specimen @@ -25648,7 +25670,7 @@ J Nutr. 2010 Feb;140(2):382-91. Epub 2009 Dec 23. a specimen that was taken from a dead organism Bjoern Peters - MO_416 postmortem + MO_416 postmortem post mortem specimen @@ -25819,10 +25841,10 @@ Dev call Nov 22, 2010: To reflect this, the term's label has been updated t - - + + @@ -25838,23 +25860,17 @@ Dev call Nov 22, 2010: To reflect this, the term's label has been updated t - - + + - - - - - - - + + labeled DNA extract a labeled specimen that is the output of a labeling process and has grain labeled DNA to be able to detect DNA in future experiments. - Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. -Added duirng Mar 1, 2010 dev call + Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. Added duirng Mar 1, 2010 dev call Group: OBI group Group: OBI group labeled DNA extract @@ -25865,19 +25881,34 @@ Added duirng Mar 1, 2010 dev call - - - - - - - - cloacal specimen + + + + + + + + + + + + + + + + + + + + + + + + + cell specimen type of sample used in the PCIRN influenza network - A specimen obtained by inserting a swab deeply into the vent of the cloaca of -an organism and vigorously swabbing the wall. The swab should be deeply -stained with fecal material and is then placed in transport medium. + A specimen obtained by inserting a swab deeply into the vent of the cloaca of an organism and vigorously swabbing the wall. The swab should be deeply stained with fecal material and is then placed in transport medium. PERSON: Melanie Courtot WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf cloacal specimen @@ -26071,18 +26102,31 @@ stained with fecal material and is then placed in transport medium. - + + + + + + + + + + + + + + + - - + + nasopharyngeal aspirate specimen type of sample used in the PCIRN influenza network - A speciemn which derives from nasopharyngeal mucosa after -aspiration. + A specimen which derives from nasopharyngeal mucosa after aspiration. PERSON: Melanie Courtot WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf nasopharyngeal aspirate specimen @@ -26208,24 +26252,37 @@ Updated both textual and logical definition. Both input and output material of f + + + + + + + + + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - nasal swab specimen type of sample used in the PCIRN influenza network - A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of -exudate and epithelial debris for microbiological or cellular examination. + A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of exudate and epithelial debris for microbiological or cellular examination. PERSON: Melanie Courtot WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf nasal swab specimen @@ -26345,10 +26402,10 @@ exudate and epithelial debris for microbiological or cellular examination. - - + + @@ -26364,23 +26421,17 @@ exudate and epithelial debris for microbiological or cellular examination. - - + + - - - - - - - + + labeled RNA extract a labeled specimen that is the output of a labeling process and has grain labeled RNA to be able to detect RNA in future experiments. - Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. -Added duirng Mar 1, 2010 dev call + Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. Added duirng Mar 1, 2010 dev call Group: OBI group Group: OBI group labeled RNA extract @@ -26394,6 +26445,7 @@ Added duirng Mar 1, 2010 dev call + @@ -26413,18 +26465,10 @@ Added duirng Mar 1, 2010 dev call - - - - - - - - frozen specimen Frozen blood plasma @@ -27124,6 +27168,7 @@ Biochimie. 2010 Feb 18. + @@ -27143,17 +27188,10 @@ Biochimie. 2010 Feb 18. - - - - - - - paraffin specimen liver tissue embedded in paraffin @@ -27244,21 +27282,24 @@ Biochimie. 2010 Feb 18. - + + + + + + processed specimen - A tissue sample that has been sliced and stained for a histology study. -A blood specimen that has been centrifuged to obtain the white blood cells. A specimen that has been intentionally physically modified. + A tissue sample that has been sliced and stained for a histology study. Bjoern Peters Bjoern Peters - A tissue sample that has been sliced and stained for a histology study. processed specimen @@ -27484,6 +27525,7 @@ A blood specimen that has been centrifuged to obtain the white blood cells. + @@ -27503,16 +27545,10 @@ A blood specimen that has been centrifuged to obtain the white blood cells. - - - - - - lyophilized specimen freezing dried DNA @@ -27688,7 +27724,6 @@ In the examples above, a reagent is an operational component of a device, but th - fresh specimen a liver freshly removed from a rat @@ -27898,25 +27933,30 @@ In the examples above, a reagent is an operational component of a device, but th - - - - - - - - - + + + + + + + + + - - + + + + + + + - - - - - - + + + + + + agar stab specimen @@ -28658,167 +28698,152 @@ JZ: based on textual definition of edited document, it can be defined as N&S - + + + + + + + nucleic acid extract + + An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen. + Person: Jie Zheng + UPenn Group + nucleic acid extract + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + ENU structure mapping assay + PMID:7002606 and PMID:2446263 + + A single-nucleotide-resolution nucleic acid structure mapping assay that determines the secondary structure of a nucleic acid at the nucleotide resolution scale which uses ENU as reagent and chemical probe + Philippe Rocca-Serra + single nucleotide resolution mapping assay using ENU probe + RNA ontology + ENU structure mapping assay + + + + + + + + - - + + + + + + + + + + + + - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + - - + + - nucleic acid extract - - An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen. - PERSON: Jie Zheng - UPenn Group - nucleic acid extract + RNASE V1 structure mapping assay + PMID:7031604 + + A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using RNAse V1 as reagent and enzymatic probe + Philippe Rocca-Serra + single nucleotide resolution mapping assay using RNAse V1 + RNA ontology + RNASE V1 structure mapping assay - + - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - ENU structure mapping assay - PMID:7002606 and PMID:2446263 - - A single-nucleotide-resolution nucleic acid structure mapping assay that determines the secondary structure of a nucleic acid at the nucleotide resolution scale which uses ENU as reagent and chemical probe - Philippe Rocca-Serra - single nucleotide resolution mapping assay using ENU probe - RNA ontology - ENU structure mapping assay - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - RNASE V1 structure mapping assay - PMID:7031604 - - A single-nucleotide-resolution ribonucleic acid structure mapping assay that determines nucleic acid secondary structure at a nucleotide resolution scale using RNAse V1 as reagent and enzymatic probe - Philippe Rocca-Serra - single nucleotide resolution mapping assay using RNAse V1 - RNA ontology - RNASE V1 structure mapping assay - - - - - - - + @@ -32185,10 +32210,10 @@ JZ: based on textual definition of edited document, it can be defined as N&S - - + + @@ -32204,25 +32229,19 @@ JZ: based on textual definition of edited document, it can be defined as N&S - - + + - - - - - - - + + labeled nucleic acid extract a labeled specimen that is the output of a labeling process and has grain labeled nucleic acid for detection of the nucleic acid in future experiments. Person: Jie Zheng labeled extract MO_221 labeledExtract - labeled extract labeled nucleic acid extract @@ -42740,26 +42759,25 @@ http://svitsrv25.epfl.ch/R-doc/library/qvalue.html - - - - - - - - - - - - - - cell specimen + + + + + + + + + + + + + cell specimen A specimen primarily composed of a cell or cells collected from a multicellular organism or a cell culture. - Discussed on obi call Jan 23, 2017. To improve cell specimen that include single cell specimen. Details see tracker: https://sourceforge.net/p/obi/obi-terms/828/ + Discussed on obi call Jan 23, 2017. To improve cell specimen that include single cell specimen. Details see tracker: https://sourceforge.net/p/obi/obi-terms/828 PERSON: Chris Stoeckert, Jie Zheng, Alexander Diehl MO_612 cell - cell specimen + cell specimen @@ -42839,27 +42857,32 @@ http://svitsrv25.epfl.ch/R-doc/library/qvalue.html - - + + - - - - - - - + + + + + + + + + + + + - + - specimen with known storage state + specimen with known storage state A specimen for which it is known whether it has been subjected to storage of a specified type. PERSON: Chris Stoeckert, Jie Zheng MO_95 BiosourceType - specimen with known storage state + specimen with known storage state @@ -43116,18 +43139,26 @@ http://svitsrv25.epfl.ch/R-doc/library/qvalue.html + - - - - - + - - - - + + + + + + + + + + + + + + + @@ -43135,13 +43166,13 @@ http://svitsrv25.epfl.ch/R-doc/library/qvalue.html - specimen from organism + specimen from organism A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm). PERSON: Chris Stoeckert, Jie Zheng - tissue specimen + tissue specimen MO_954 organism_part - specimen from organism + specimen from organism @@ -44072,46 +44103,51 @@ http://svitsrv25.epfl.ch/R-doc/library/qvalue.html - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + - - specimen with pre- or post-mortem status + + specimen with pre- or post-mortem status A specimen that has been established to be taken from a live (pre-mortem) or dead (post-mortem) organism. organizational term, used in description of specimen that is created from known pre- or post-mortem status PERSON: Chris Stoeckert, Jie Zheng MO_84 OrganismStatus - specimen with pre- or post-mortem status + specimen with pre- or post-mortem status @@ -65257,7 +65293,7 @@ Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries. - + assay for transposase-accessible chromatin using sequencing Kasinathan et al., (February 2014). "High-resolution mapping of transcription factor binding sites on natitve chromatin." Nat Methods 11(2):203-9. doi: 10.1038/nmeth.2766. @@ -68028,8 +68064,7 @@ https://www.doi.org/ - - + @@ -68039,13 +68074,14 @@ https://www.doi.org/ - - H&E-stained fixed tissue slide specimen + + + H&E-stained fixed tissue slide specimen A fixed tissue slide specimen that is the output of H&E slide staining. - Chris Stoeckert, Ned Haubein - OBIB, OBI - H&E-stained fixed tissue slide specimen + Chris Stoeckert, Ned Haubein + OBIB, OBI + H&E-stained fixed tissue slide specimen @@ -68053,8 +68089,7 @@ https://www.doi.org/ - - + @@ -68064,14 +68099,14 @@ https://www.doi.org/ - - IHC-stained fixed tissue slide specimen + + + IHC-stained fixed tissue slide specimen A fixed tissue slide specimen that is the output of immunohistochemistry slide staining. - Chris Stoeckert, Ned Haubein - immunohistochemistry slide specimen - OBIB, OBI - IHC-stained fixed tissue slide specimen + Chris Stoeckert, Ned Haubein + OBIB, OBI + IHC-stained fixed tissue slide specimen @@ -68080,13 +68115,13 @@ https://www.doi.org/ - single cell specimen + single cell specimen A cell specimen that contains only one cell. Requested by Sirarat Sarntivijai (EBI). Details see tracker: https://sourceforge.net/p/obi/obi-terms/828/ PERSON: Jie Zheng, Alexander Diehl PERSON: Jie Zheng, Alexander Diehl - single cell specimen + single cell specimen @@ -73146,9 +73181,9 @@ https://www.doi.org/ + - @@ -73159,15 +73194,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73188,9 +73218,9 @@ https://www.doi.org/ + - @@ -73201,15 +73231,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73230,9 +73255,9 @@ https://www.doi.org/ + - @@ -73243,15 +73268,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73272,9 +73292,9 @@ https://www.doi.org/ + - @@ -73285,15 +73305,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73315,9 +73330,9 @@ https://www.doi.org/ + - @@ -73328,15 +73343,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73358,9 +73368,9 @@ https://www.doi.org/ + - @@ -73371,15 +73381,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73400,9 +73405,9 @@ https://www.doi.org/ + - @@ -73413,15 +73418,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73442,9 +73442,9 @@ https://www.doi.org/ + - @@ -73455,15 +73455,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73484,9 +73479,9 @@ https://www.doi.org/ + - @@ -73497,15 +73492,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73526,9 +73516,9 @@ https://www.doi.org/ + - @@ -73539,15 +73529,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73568,9 +73553,9 @@ https://www.doi.org/ + - @@ -73581,15 +73566,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73610,9 +73590,9 @@ https://www.doi.org/ + - @@ -73633,15 +73613,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73663,9 +73638,9 @@ https://www.doi.org/ + - @@ -73676,15 +73651,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73705,9 +73675,9 @@ https://www.doi.org/ + - @@ -73728,15 +73698,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73757,9 +73722,9 @@ https://www.doi.org/ + - @@ -73770,15 +73735,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73799,9 +73759,9 @@ https://www.doi.org/ + - @@ -73812,15 +73772,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73841,9 +73796,9 @@ https://www.doi.org/ + - @@ -73864,15 +73819,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73893,9 +73843,9 @@ https://www.doi.org/ + - @@ -73906,15 +73856,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73935,9 +73880,9 @@ https://www.doi.org/ + - @@ -73958,15 +73903,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -73987,9 +73927,9 @@ https://www.doi.org/ + - @@ -74000,15 +73940,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74029,9 +73964,9 @@ https://www.doi.org/ + - @@ -74052,15 +73987,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74081,9 +74011,9 @@ https://www.doi.org/ + - @@ -74104,15 +74034,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74134,9 +74059,9 @@ https://www.doi.org/ + - @@ -74157,15 +74082,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74186,9 +74106,9 @@ https://www.doi.org/ + - @@ -74209,15 +74129,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74239,9 +74154,9 @@ https://www.doi.org/ + - @@ -74262,15 +74177,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74291,9 +74201,9 @@ https://www.doi.org/ + - @@ -74314,15 +74224,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74343,9 +74248,9 @@ https://www.doi.org/ + - @@ -74366,15 +74271,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74396,9 +74296,9 @@ https://www.doi.org/ + - @@ -74419,15 +74319,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74448,9 +74343,9 @@ https://www.doi.org/ + - @@ -74471,15 +74366,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74500,9 +74390,9 @@ https://www.doi.org/ + - @@ -74523,15 +74413,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74552,9 +74437,9 @@ https://www.doi.org/ + - @@ -74565,15 +74450,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74594,9 +74474,9 @@ https://www.doi.org/ + - @@ -74617,15 +74497,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74647,9 +74522,9 @@ https://www.doi.org/ + - @@ -74670,15 +74545,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74699,9 +74569,9 @@ https://www.doi.org/ + - @@ -74722,15 +74592,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74751,9 +74616,9 @@ https://www.doi.org/ + - @@ -74774,15 +74639,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74803,9 +74663,9 @@ https://www.doi.org/ + - @@ -74826,15 +74686,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74856,9 +74711,9 @@ https://www.doi.org/ + - @@ -74879,15 +74734,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74909,9 +74759,9 @@ https://www.doi.org/ + - @@ -74932,15 +74782,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -74961,9 +74806,9 @@ https://www.doi.org/ + - @@ -74984,15 +74829,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75014,9 +74854,9 @@ https://www.doi.org/ + - @@ -75037,15 +74877,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75066,9 +74901,9 @@ https://www.doi.org/ + - @@ -75089,15 +74924,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75118,9 +74948,9 @@ https://www.doi.org/ + - @@ -75141,15 +74971,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75170,9 +74995,9 @@ https://www.doi.org/ + - @@ -75193,15 +75018,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75222,9 +75042,9 @@ https://www.doi.org/ + - @@ -75245,15 +75065,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75274,9 +75089,9 @@ https://www.doi.org/ + - @@ -75297,15 +75112,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75326,9 +75136,9 @@ https://www.doi.org/ + - @@ -75349,15 +75159,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75378,9 +75183,9 @@ https://www.doi.org/ + - @@ -75401,15 +75206,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75430,9 +75230,9 @@ https://www.doi.org/ + - @@ -75453,15 +75253,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75482,9 +75277,9 @@ https://www.doi.org/ + - @@ -75505,15 +75300,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75534,9 +75324,9 @@ https://www.doi.org/ + - @@ -75557,15 +75347,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75586,9 +75371,9 @@ https://www.doi.org/ + - @@ -75609,15 +75394,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75638,9 +75418,9 @@ https://www.doi.org/ + - @@ -75661,15 +75441,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75690,9 +75465,9 @@ https://www.doi.org/ + - @@ -75713,15 +75488,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75742,9 +75512,9 @@ https://www.doi.org/ + - @@ -75765,15 +75535,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -75794,9 +75559,9 @@ https://www.doi.org/ + - @@ -75817,15 +75582,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -76195,7 +75955,6 @@ https://www.doi.org/ PERSON: Chris Stoeckert PERSON: Jie Zheng UPenn Group - 2018-05-11T16:35:11Z polyA depleted RNA extract @@ -76664,10 +76423,15 @@ https://www.doi.org/ - - - - + + + + + + + + + swab specimen @@ -76732,37 +76496,29 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + areolar swab specimen @@ -76780,37 +76536,29 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + breast swab specimen @@ -76828,37 +76576,29 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + cheek swab specimen @@ -76876,37 +76616,29 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + nasopharyngeal swab specimen @@ -76924,37 +76656,29 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + oral swab specimen @@ -76972,37 +76696,29 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + oropharyngeal swab specimen @@ -77020,37 +76736,29 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + rectal swab specimen @@ -77068,37 +76776,29 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + tongue swab specimen @@ -77116,37 +76816,29 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + vagina swab specimen @@ -77164,37 +76856,29 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + fecal swab specimen @@ -77213,34 +76897,25 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -77515,7 +77190,7 @@ https://www.doi.org/ An extract of RNA which is produced through rRNA (ribosomal RNA) depletion (the removal of highly abundant rRNA species). Dan Berrios - https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-4585-1 + https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-4585-1 ribosomal RNA-depleted RNA extract @@ -78689,14 +78364,19 @@ https://www.doi.org/ + + + + + + + 1 + + + + + - - - - 1 - - - individual organism specimen A specimen composed of an individual organism to be studied in an investigation. @@ -80067,7 +79747,13 @@ https://www.doi.org/ - + + + + + + + arthropod meal of blood specimen A specimen used in a blood meal assay to determine what is the source of blood ingested by a mosquito. @@ -82063,7 +81749,6 @@ JZ (3-30-20): discussed on the OBI call. Since the REO was never actually regist - @@ -82076,15 +81761,10 @@ JZ (3-30-20): discussed on the OBI call. Since the REO was never actually regist - - - - - - - - - + + + + induced sputum specimen @@ -82670,11 +82350,11 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - platelet-poor plasma specimen + platelet-poor plasma specimen A blood plasma specimen that is the output of some platelet-poor plasma preparation and is the portion of plasma that contains fewer than 10,000 platelets per microliter. - PERSON: Matthew Diller - platelet-poor plasma specimen + PERSON: Matthew Diller + platelet-poor plasma specimen @@ -82725,38 +82405,28 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + - - - - - - - - - + + + + - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + tracheal aspirate specimen @@ -82775,37 +82445,29 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + mid-turbinate nasal swab specimen @@ -82823,38 +82485,29 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + - + nasal aspirate specimen A specimen that is collected with a suctioning tube from the nasal cavity. @@ -82873,34 +82526,25 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -82922,37 +82566,29 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + upper respiratory specimen @@ -82970,7 +82606,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + @@ -82988,7 +82624,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + lower respiratory tract specimen A specimen that is derived from the lower respiratory tract. @@ -83005,37 +82641,29 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + anterior nasal swab specimen @@ -85083,7 +84711,6 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - @@ -85096,15 +84723,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + endotracheal tube specimen @@ -85123,7 +84745,6 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - @@ -85136,15 +84757,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + endotracheal aspirate specimen @@ -87298,11 +86914,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + - @@ -87315,15 +86930,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + blood specimen in vacutainer @@ -87339,11 +86949,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + - @@ -87356,15 +86965,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + blood specimen on filter paper @@ -91491,7 +91095,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + umbilical cord blood assay An assay that has an umbilical cord blood specimen as evaluant. @@ -92136,7 +91740,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + umbilical cord blood assay datum A data item that is the specified output of an umbilical cord blood assay. @@ -94999,9 +94603,9 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + - @@ -95012,19 +94616,14 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + - + placental blood specimen A specimen that is derived from placental blood. @@ -95669,11 +95268,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + - @@ -95686,15 +95284,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + peripheral blood mononuclear cell specimen @@ -98036,7 +97629,6 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - @@ -98059,15 +97651,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + lymph specimen @@ -98086,7 +97673,6 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - @@ -98109,15 +97695,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + digestive tract specimen @@ -101456,6 +101037,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + serum anti-Epstein-Barr virus antibody level assay An antigen specific antibodies assay that is meant to detect antibodies that bind to Epstein-Barr virus (EBV) antigens in a serum sample. @@ -101510,6 +101092,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + serum anti-cytomegalovirus antibody level assay A CMV antibody assay that has serum as an input. @@ -101596,34 +101179,25 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -103097,24 +102671,29 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + + + + + + + + + + + + + + + - - - - - - - - - - albumin-free serum A blood serum specimen that contains no albumin. Sebastian Duesing https://github.com/obi-ontology/obi/issues/493 Philippe Rocca-Serra - albumin-free serum + albumin-free serum @@ -103543,7 +103122,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + @@ -103552,6 +103131,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + lavage fluid specimen The collection of bronchoalveolar lavage fluid (BAL) from the lungs of mice in order to study the cytokines present. @@ -103569,34 +103149,25 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -103687,6 +103258,43 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + + + + + chromatin accessibility assay + + An assay that determines which regions of a DNA molecule are in the form of euchromatin and thus able to make direct physical contact with (i.e. are accessible to) other molecules such as RNA polymerase, transcription factors, etc. + Bjoern Peters + Michelle Giglio + Sebastian Duesing + Michelle Giglio + https://github.com/obi-ontology/obi/issues/1813 + Jennifer Jou + chromatin accessibility assay + + + + + + + + + m6A-MTase sequencing assay + https://pubmed.ncbi.nlm.nih.gov/32587015/ + + A DNA methylation profiling assay in which chromatin stencils are created by treating nuclei with m6A methyltransferase (MTase) and then sequenced using single-molecule circular consensus sequencing to identify regions of accessible DNA at nucleotide resolution. + Jennifer Jou + Sebastian Duesing + Fiber-seq + Jennifer Jou + https://github.com/obi-ontology/obi/issues/1813 + Jennifer Jou + m6A-MTase sequencing assay + + + + @@ -103777,18 +103385,8 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + - - - - - - - - - - - @@ -103805,17 +103403,17 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - blood plasma specimen - PMID: 18217225.Sex Transm Dis. 2008 Jan;35(1):55-60. Review.Human immunodeficiency virus viral load in blood plasma and semen: review and implications of empirical findings. + blood plasma specimen + PMID: 18217225.Sex Transm Dis. 2008 Jan;35(1):55-60. Review.Human immunodeficiency virus viral load in blood plasma and semen: review and implications of empirical findings. a material entity which corresponds to the liquid component of blood, in which the blood cells are suspended. - 03/21/2010: BP, blood plasma is defined as the output of certain separation processes, so this is in the domain of OBI, not FMA. - PERSON: Maura Gasparetto - PERSON: Melanie Courtot + 03/21/2010: BP, blood plasma is defined as the output of certain separation processes, so this is in the domain of OBI, not FMA. + PERSON: Maura Gasparetto + PERSON: Melanie Courtot PERSON: Philippe Rocca-Serra - plasma - WEB: http://en.wikipedia.org/wiki/Blood_plasma - blood plasma specimen + plasma + WEB: http://en.wikipedia.org/wiki/Blood_plasma + blood plasma specimen @@ -103823,7 +103421,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + @@ -103846,21 +103444,15 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - blood serum specimen - PMID: 18229666.Adv Med Sci. 2007;52 Suppl 1:204-6.Antioxidant activity of blood serum and saliva in patients with periodontal disease treated due to epilepsy. + blood serum specimen + PMID: 18229666.Adv Med Sci. 2007;52 Suppl 1:204-6.Antioxidant activity of blood serum and saliva in patients with periodontal disease treated due to epilepsy. A material entity which derives from blood and corresponds to blood plasma without fibrinogen or the other clotting factors. - PERSON: Maura Gasparetto - PERSON: Melanie Courtot + PERSON: Maura Gasparetto + PERSON: Melanie Courtot PERSON: Philippe Rocca-Serra - WEB: http://en.wikipedia.org/wiki/Blood_plasma - blood serum specimen + WEB: http://en.wikipedia.org/wiki/Blood_plasma + blood serum specimen @@ -104003,10 +103595,9 @@ This issue is outside the scope of OBI. specimen - Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen. + Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen; collecting a stone from a site. - A material entity that has the specimen role. - Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation. + A material entity that is collected for potential use as an input upon which measurements or observations are performed. PERSON: James Malone PERSON: Philippe Rocca-Serra GROUP: OBI Biomaterial Branch @@ -104284,27 +103875,38 @@ Thyroidectomy during laryngectomy for advanced laryngeal carcinoma--whole organ - - - - - - - - - - - - - - bronchial alveolar lavage - solution containing lung derived T cells, eosinophils, and TNFa. + + + + + + + + + + + + + + + + + + + + + + + + + bronchial alveolar lavage + solution containing lung derived T cells, eosinophils, and TNFa. Group of biomaterials present in the bronchial aveolar space of an organism which are collected through lavage including the reagents used to for the lavage process, organisms, cells, and cellular secretions present in the bronchial aveolar space. - PERSON: Bjoern Peters - BAL - GROUP: IEDB - bronchial alveolar lavage + PERSON: Bjoern Peters + BAL + GROUP: IEDB + bronchial alveolar lavage @@ -108401,13 +108003,13 @@ determinations of compounds. - pool of specimens + pool of specimens A pool of specimens is a mixture of a population of samples which have been gathered from one or more sample populations, obtained by the physical process of mixing individual specimens, e.g. mixing the DNA collected from the individual fish. - check with advisors as to how to represent multiple instances of any class? a set of specimens which have been gathered from one or more sample_populations, obtained by the physical process of mixing individual specimens, e.g. mixing the DNA collected from the individual fish + check with advisors as to how to represent multiple instances of any class? a set of specimens which have been gathered from one or more sample_populations, obtained by the physical process of mixing individual specimens, e.g. mixing the DNA collected from the individual fish PERSON: Jennifer Fostel GROUP: CEBS - pool of specimens + pool of specimens @@ -115024,7 +114626,6 @@ Possible ecological risks of transgenic organism release when transgenes affect - @@ -115037,16 +114638,16 @@ Possible ecological risks of transgenic organism release when transgenes affect - whole mount tissue + whole mount tissue A whole organism preparation resulting from a histological preparation known as whole mount preparation where the whole specimen is mounted or spread on the microscope (glass) slide - PERSON: Helen Parkinson + PERSON: Helen Parkinson PERSON: Philippe Rocca-Serra - whole mount sample - GROUP: OBI - PRS:22-02-2008: indicates the need to create a protocol application and distinguish it from this entity - PRS:22-02-2008: is a material which has output_role during whole mount preparation protocol-application - whole mount tissue + whole mount sample + GROUP: OBI + PRS:22-02-2008: indicates the need to create a protocol application and distinguish it from this entity + PRS:22-02-2008: is a material which has output_role during whole mount preparation protocol-application + whole mount tissue @@ -115887,30 +115488,35 @@ Possible ecological risks of transgenic organism release when transgenes affect + + + + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - - - - - lymph node cell specimen A cell specimen comprised of a mixed population of cells obtained by processing whole lymph node into individual cells, typically performed using a sieve. This population includes T cells, B cells, macrophages, and other cell types. - IEDB - IEDB - lymph node cell specimen + IEDB + IEDB + lymph node cell specimen @@ -116878,30 +116484,35 @@ MHB 3-5-13: Need to review axiom on this class in light of clarification that it + + + + + + + + + + + + + + + + + + + + + - - - - - - - - - - - - - - - - splenocyte specimen A cell specimen comprised of a mixed cell population obtained by processing whole spleen into individual cells, typically performed using a sieve or blender. This population includes T cells, B cells, macrophages, and other cell types. - IEDB - IEDB - splenocyte specimen + IEDB + IEDB + splenocyte specimen @@ -118957,15 +118568,13 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 FFPE specimen - Many of today’s researchers prefer to use Formalin-Fixed Paraffin-Embedded samples of tissues for their IHC, histological or in-situ genomic analyses. Professionally fixed and embedded FFPE samples and the biomolecules they contain are reasonably stable at ambient temperatures. - --based on https://lab-ally.com/histopathology-resources/ffpe-samples/ + Many of today’s researchers prefer to use Formalin-Fixed Paraffin-Embedded samples of tissues for their IHC, histological or in-situ genomic analyses. Professionally fixed and embedded FFPE samples and the biomolecules they contain are reasonably stable at ambient temperatures. -based on https://lab-ally.com/histopathology-resources/ffpe-samples/ A specimen that has been fixed in formalin and embedded in paraffin. MIABIS formalin-fixed paraffin-embeded specimen - - + https://www.biochain.com/general/what-is-ffpe-tissue/ + https://github.com/obi-ontology/obi/issues/1019 FFPE specimen @@ -118977,9 +118586,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119000,15 +118609,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -119031,9 +118635,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119054,15 +118658,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -119085,9 +118684,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119098,15 +118697,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -119129,9 +118723,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119152,15 +118746,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -119183,9 +118772,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119206,15 +118795,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -119237,9 +118821,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119260,15 +118844,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -119291,9 +118870,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119314,15 +118893,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -119345,9 +118919,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119368,15 +118942,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -119399,9 +118968,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119412,15 +118981,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -119443,9 +119007,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119456,15 +119020,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -119487,9 +119046,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119510,15 +119069,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -119541,9 +119095,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119554,15 +119108,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -119585,9 +119134,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119598,15 +119147,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -119629,9 +119173,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119642,19 +119186,14 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + - + arterial blood specimen A specimen that is derived from some arterial blood @@ -119673,9 +119212,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119686,19 +119225,14 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + - + venous blood specimen A specimen that is derived from some venous blood @@ -119717,9 +119251,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -119730,19 +119264,14 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + - + capillary blood specimen A specimen that is derived from some capillary blood @@ -119758,38 +119287,29 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - - - - - - - - - + + + + - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + erythrocyte specimen @@ -119806,38 +119326,29 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - - - - - - - - - + + + + - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + reticulocyte specimen @@ -119854,38 +119365,29 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - - - - - - - - - + + + + - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + leukocyte specimen @@ -121842,6 +121344,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -121915,6 +121418,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -121988,6 +121492,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122061,6 +121566,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122135,6 +121641,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122195,6 +121702,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122255,6 +121763,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122315,6 +121824,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122375,6 +121885,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122434,6 +121945,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122508,6 +122020,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122568,6 +122081,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122628,6 +122142,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122688,6 +122203,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122747,6 +122263,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122820,6 +122337,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122893,6 +122411,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -122966,6 +122485,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123039,6 +122559,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123112,6 +122633,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123185,6 +122707,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123258,6 +122781,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123332,6 +122856,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123392,6 +122917,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123452,6 +122978,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123512,6 +123039,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123571,6 +123099,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123645,6 +123174,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123704,6 +123234,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123778,6 +123309,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123850,6 +123382,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123923,6 +123456,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -123996,6 +123530,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -124069,6 +123604,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -124142,6 +123678,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -124215,6 +123752,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -124288,6 +123826,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -124361,6 +123900,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -124434,6 +123974,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -124507,6 +124048,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -124580,6 +124122,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -124653,6 +124196,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -124726,6 +124270,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -124799,6 +124344,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -124873,6 +124419,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -124932,6 +124479,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125006,6 +124554,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125079,6 +124628,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125139,6 +124689,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125199,6 +124750,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125259,6 +124811,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125319,6 +124872,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125379,6 +124933,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125439,6 +124994,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125499,6 +125055,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125558,6 +125115,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125631,6 +125189,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125704,6 +125263,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125777,6 +125337,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125837,6 +125398,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125910,6 +125472,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -125983,6 +125546,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -126056,6 +125620,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -126129,6 +125694,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -126202,7 +125768,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - + @@ -126263,6 +125829,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -126335,6 +125902,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -126408,6 +125976,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -126481,6 +126050,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -126614,6 +126184,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -126687,6 +126258,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -126761,6 +126333,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -126820,6 +126393,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -126893,6 +126467,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -126966,6 +126541,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -127039,6 +126615,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -127112,6 +126689,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -127185,6 +126763,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -127258,6 +126837,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -127332,6 +126912,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -127391,6 +126972,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -127464,6 +127046,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -127538,6 +127121,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -127610,6 +127194,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -127966,6 +127551,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -128039,6 +127625,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -128112,6 +127699,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -128333,6 +127921,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -128394,6 +127983,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -128453,6 +128043,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -128526,6 +128117,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -128599,6 +128191,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -128672,6 +128265,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -128745,6 +128339,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -128818,6 +128413,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -128891,6 +128487,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -128964,6 +128561,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -129037,6 +128635,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -129110,6 +128709,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -129183,6 +128783,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -129256,6 +128857,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -129329,6 +128931,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -129402,6 +129005,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -129462,6 +129066,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -129522,6 +129127,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -129583,6 +129189,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -129642,6 +129249,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -129715,6 +129323,7 @@ The content of that report on the IEDB website is here: 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http://iedb.org/refId/10 + @@ -144689,6 +144478,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -144748,6 +144538,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -144821,6 +144612,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -144895,6 +144687,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -144954,6 +144747,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -145028,6 +144822,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -145087,6 +144882,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -145160,6 +144956,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -145233,6 +145030,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -145306,6 +145104,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -145379,6 +145178,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -145879,6 +145679,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -145952,6 +145753,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -146025,6 +145827,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -146098,6 +145901,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -146171,6 +145975,7 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + @@ -148193,6 +147998,18 @@ realizes some 'host of immune response role' + + + + + cloaca + Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures. + + cloaca + + + + diff --git a/views/NIAID-GSC-BRC.owl b/views/NIAID-GSC-BRC.owl index 1f196382..3ac385be 100644 --- a/views/NIAID-GSC-BRC.owl +++ b/views/NIAID-GSC-BRC.owl @@ -11,7 +11,7 @@ xmlns:terms="http://purl.org/dc/terms/" xmlns:protege="http://protege.stanford.edu/plugins/owl/protege#"> - + en Advisors for this project come from the IFOMIS group, Saarbruecken and from the Co-ODE group in Manchester Alan Ruttenberg @@ -77,7 +77,7 @@ http://creativecommons.org/licenses/by/4.0/ Ontology for Biomedical Investigations Please cite the OBI consortium http://purl.obolibrary.org/obo/obi where traditional citation is called for. However it is adequate that individual terms be attributed simply by use of the identifying PURL for the term, in projects that refer to them. - 2024-10-25 + 2024-12-05 @@ -2610,7 +2610,7 @@ Modification made by JZ. specimen role liver section; a portion of a culture of cells; a nemotode or other animal once no longer a subject (generally killed); portion of blood from a patient. - a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation + A role borne by a material entity that is obtained during a specimen collection process and that can be realized by performing measurements or observations on the specimen. 22Jun09. The definition includes whole organisms, and can include a human. The link between specimen role and study subject role has been removed. A specimen taken as part of a case study is not considered to be a population representative, while a specimen taken as representing a population, e.g. person taken from a cohort, blood specimen taken from an animal) would be considered a population representative and would also bear material sample role. Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation. blood taken from animal: animal continues in study, whereas blood has role specimen. @@ -3072,9 +3072,10 @@ that has_part some material entity is a material entity. If we add as equivalent specimen collection process - drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation + drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation, collecting a stone from a site - A planned process with the objective of collecting a specimen. + A planned process with the objective to obtain a material entity for potential use as an input upon which measurements or observations are performed. + Definition updated following discussion on 2024-10-07 OBI dev call. Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation. Philly2013: A specimen collection can have as part a material entity acquisition, such as ordering from a bank. The distinction is that specimen collection necessarily involves the creation of a specimen role. However ordering cell lines cells from ATCC for use in an investigation is NOT a specimen collection, because the cell lines already have a specimen role. Philly2013: The specimen_role for the specimen is created during the specimen collection process. @@ -3095,10 +3096,7 @@ http://sourceforge.net/p/obi/obi-terms/716/ - - - - + @@ -3108,12 +3106,6 @@ http://sourceforge.net/p/obi/obi-terms/716/ - - - - - - sample from organism a material obtained from an organism in order to be a representative of the whole @@ -3180,7 +3172,8 @@ http://sourceforge.net/p/obi/obi-terms/716/ specimen collection objective The objective to collect bits of excrement in the rainforest. The objective to obtain a blood sample from a patient. - A objective specification to obtain a material entity for potential use as an input during an investigation. + A objective specification that is fulfilled by obtaining a material entity for potential use as an input upon which measurements or observations are performed. + OBI recommends against subclassing this term in order to avoid further parallel hierarchies between this term and specimen collection process. Bjoern Peters Bjoern Peters specimen collection objective @@ -3237,7 +3230,7 @@ http://sourceforge.net/p/obi/obi-terms/716/ - + @@ -3251,6 +3244,7 @@ http://sourceforge.net/p/obi/obi-terms/716/ A material entity that has the material sample role OBI: workshop + sample sample population material sample @@ -3442,21 +3436,24 @@ http://sourceforge.net/p/obi/obi-terms/716/ - + + + + + + processed specimen - A tissue sample that has been sliced and stained for a histology study. -A blood specimen that has been centrifuged to obtain the white blood cells. A specimen that has been intentionally physically modified. + A tissue sample that has been sliced and stained for a histology study. Bjoern Peters Bjoern Peters - A tissue sample that has been sliced and stained for a histology study. processed specimen @@ -3547,32 +3544,17 @@ In the examples above, a reagent is an operational component of a device, but th - - - - - - - - - - - - - - - - - + + nucleic acid extract An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen. - PERSON: Jie Zheng + Person: Jie Zheng UPenn Group nucleic acid extract @@ -3711,32 +3693,63 @@ All subtype will be defined by textual definition now. + + + + + + + + + + + + + + + + cell specimen + + A specimen primarily composed of a cell or cells collected from a multicellular organism or a cell culture. + Discussed on obi call Jan 23, 2017. To improve cell specimen that include single cell specimen. Details see tracker: https://sourceforge.net/p/obi/obi-terms/828 + PERSON: Chris Stoeckert, Jie Zheng, Alexander Diehl + MO_612 cell + cell specimen + + + + - - + + - - - - - - - + + + + + + + + + + + + - + - specimen with known storage state + specimen with known storage state A specimen for which it is known whether it has been subjected to storage of a specified type. PERSON: Chris Stoeckert, Jie Zheng MO_95 BiosourceType - specimen with known storage state + specimen with known storage state @@ -3747,18 +3760,26 @@ All subtype will be defined by textual definition now. + - - - - - + - - - - + + + + + + + + + + + + + + + @@ -3766,14 +3787,14 @@ All subtype will be defined by textual definition now. - specimen from organism + specimen from organism A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm). PERSON: Chris Stoeckert, Jie Zheng - tissue specimen + tissue specimen MO_954 organism_part CS16 - specimen from organism + specimen from organism @@ -5722,10 +5743,9 @@ This issue is outside the scope of OBI. specimen - Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen. + Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen; collecting a stone from a site. - A material entity that has the specimen role. - Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation. + A material entity that is collected for potential use as an input upon which measurements or observations are performed. PERSON: James Malone PERSON: Philippe Rocca-Serra GROUP: OBI Biomaterial Branch @@ -5969,39 +5989,6 @@ A cultured cell population maintained in vitro: "Rat cortical neurons from - - - - - - - - - - - - - - - - - - - - - - - collecting specimen from organism - taking a sputum sample from a cancer patient, taking the spleen from a killed mouse, collecting a urine sample from a patient - - a process with the objective to obtain a material entity that was part of an organism for potential future use in an investigation - PERSON:Bjoern Peters - IEDB - collecting specimen from organism - - - - diff --git a/views/obi-base.owl b/views/obi-base.owl index b2770f24..28cc2006 100644 --- a/views/obi-base.owl +++ b/views/obi-base.owl @@ -13,7 +13,7 @@ xmlns:protege="http://protege.stanford.edu/plugins/owl/protege#" xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - + en Ontology for Biomedical Investigations Advisors for this project come from the IFOMIS group, Saarbruecken and from the Co-ODE group in Manchester @@ -80,7 +80,7 @@ http://creativecommons.org/licenses/by/4.0/ Ontology for Biomedical Investigations Please cite the OBI consortium http://purl.obolibrary.org/obo/obi where traditional citation is called for. However it is adequate that individual terms be attributed simply by use of the identifying PURL for the term, in projects that refer to them. - 2024-10-03 + 2024-12-05 @@ -5725,7 +5725,7 @@ editor = PRS specimen role liver section; a portion of a culture of cells; a nemotode or other animal once no longer a subject (generally killed); portion of blood from a patient. - a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation + A role borne by a material entity that is obtained during a specimen collection process and that can be realized by performing measurements or observations on the specimen. 22Jun09. The definition includes whole organisms, and can include a human. The link between specimen role and study subject role has been removed. A specimen taken as part of a case study is not considered to be a population representative, while a specimen taken as representing a population, e.g. person taken from a cohort, blood specimen taken from an animal) would be considered a population representative and would also bear material sample role. Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation. blood taken from animal: animal continues in study, whereas blood has role specimen. @@ -13291,25 +13291,29 @@ Eur J Cancer. 2009 Jan;45(1):74-81. PMID: 19008094 - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + urine specimen a portion of urine collected from an organism @@ -13394,25 +13398,29 @@ Eur J Cancer. 2009 Jan;45(1):74-81. PMID: 19008094 - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + blood specimen blood drawn from a human for glucose assay @@ -13491,9 +13499,10 @@ Eur J Cancer. 2009 Jan;45(1):74-81. PMID: 19008094 - drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation + drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation, collecting a stone from a site - A planned process with the objective of collecting a specimen. + A planned process with the objective to obtain a material entity for potential use as an input upon which measurements or observations are performed. + Definition updated following discussion on 2024-10-07 OBI dev call. Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation. Philly2013: A specimen collection can have as part a material entity acquisition, such as ordering from a bank. The distinction is that specimen collection necessarily involves the creation of a specimen role. However ordering cell lines cells from ATCC for use in an investigation is NOT a specimen collection, because the cell lines already have a specimen role. Philly2013: The specimen_role for the specimen is created during the specimen collection process. @@ -13796,10 +13805,7 @@ http://sourceforge.net/p/obi/obi-terms/716/ - - - - + @@ -13807,13 +13813,6 @@ http://sourceforge.net/p/obi/obi-terms/716/ - - - - - - - sample from organism a material obtained from an organism in order to be a representative of the whole @@ -13939,24 +13938,7 @@ http://sourceforge.net/p/obi/obi-terms/716/ - - - - - - - - - - - - - - - - - - + @@ -14007,7 +13989,8 @@ http://sourceforge.net/p/obi/obi-terms/716/ The objective to collect bits of excrement in the rainforest. The objective to obtain a blood sample from a patient. - A objective specification to obtain a material entity for potential use as an input during an investigation. + A objective specification that is fulfilled by obtaining a material entity for potential use as an input upon which measurements or observations are performed. + OBI recommends against subclassing this term in order to avoid further parallel hierarchies between this term and specimen collection process. Bjoern Peters Bjoern Peters specimen collection objective @@ -15941,7 +15924,7 @@ the role 'adjuvant role' inheres in some 'material entity' a - + @@ -15954,9 +15937,9 @@ the role 'adjuvant role' inheres in some 'material entity' a A material entity that has the material sample role OBI: workshop + sample sample population - - sample + https://github.com/obi-ontology/obi/issues/1013 material sample @@ -18177,39 +18160,42 @@ placeholder - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + - - pre-mortem specimen material obtained through a liver biopsy from a human patient a specimen that was taken from a live organism Bjoern Peters - MO_705 premortem + MO_705 premortem pre-mortem specimen @@ -18362,8 +18348,7 @@ placeholder Cytoplasmic RNA extraction from mammalian tissues to create cDNA library (Carninci P, Nakamura M, Sato K, Hayashizaki Y, Brownstein MJ. Cytoplasmic RNA extraction from fresh and frozen mammalian tissues. Biotechniques. 2002;33:306–309.) A RNA extract that is the output of a RNA extraction process in which RNA molecules found in the cytoplasm are extracted. - PERSON: Chris Stoeckert - PERSON: Jie Zheng + PERSON:Chris Stoeckert UPenn Group cytoplasmic RNA extract @@ -18783,7 +18768,7 @@ J Nutr. 2010 Feb;140(2):382-91. Epub 2009 Dec 23. total RNA extract - Extraction of total RNA from cells with Qiagen mini RNeasy kit. + Extraction of total RNA from cells with Qiagen mini RNeasy kit A RNA extract that is the output of an extraction process in which total celluar and organelle RNA molecules are isolated from a specimen. PERSON: Chris Stoeckert @@ -18879,38 +18864,42 @@ J Nutr. 2010 Feb;140(2):382-91. Epub 2009 Dec 23. - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + - post mortem specimen the spleen taken from a dead mouse a specimen that was taken from a dead organism Bjoern Peters - MO_416 postmortem + MO_416 postmortem post mortem specimen @@ -19074,10 +19063,10 @@ Dev call Nov 22, 2010: To reflect this, the term's label has been updated t - - + + @@ -19093,23 +19082,16 @@ Dev call Nov 22, 2010: To reflect this, the term's label has been updated t - - + + - - - - - - - + labeled DNA extract a labeled specimen that is the output of a labeling process and has grain labeled DNA to be able to detect DNA in future experiments. - Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. -Added duirng Mar 1, 2010 dev call + Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. Added duirng Mar 1, 2010 dev call Group: OBI group Group: OBI group labeled DNA extract @@ -19120,19 +19102,33 @@ Added duirng Mar 1, 2010 dev call - - - - - - - - cloacal specimen + + + + + + + + + + + + + + + + + + + + + + + + cell specimen type of sample used in the PCIRN influenza network - A specimen obtained by inserting a swab deeply into the vent of the cloaca of -an organism and vigorously swabbing the wall. The swab should be deeply -stained with fecal material and is then placed in transport medium. + A specimen obtained by inserting a swab deeply into the vent of the cloaca of an organism and vigorously swabbing the wall. The swab should be deeply stained with fecal material and is then placed in transport medium. PERSON: Melanie Courtot WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf cloacal specimen @@ -19319,18 +19315,31 @@ stained with fecal material and is then placed in transport medium. - + + + + + + + + + + + + + + + - - + + nasopharyngeal aspirate specimen type of sample used in the PCIRN influenza network - A speciemn which derives from nasopharyngeal mucosa after -aspiration. + A specimen which derives from nasopharyngeal mucosa after aspiration. PERSON: Melanie Courtot WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf nasopharyngeal aspirate specimen @@ -19453,24 +19462,35 @@ Updated both textual and logical definition. Both input and output material of f - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + nasal swab specimen type of sample used in the PCIRN influenza network - A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of -exudate and epithelial debris for microbiological or cellular examination. + A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of exudate and epithelial debris for microbiological or cellular examination. PERSON: Melanie Courtot WEB: http://www.wpro.who.int/NR/rdonlyres/EFD2B9A7-2265-4AD0-BC98-97937B4FA83C/0/manualonanimalaidiagnosisandsurveillance.pdf nasal swab specimen @@ -19587,10 +19607,10 @@ exudate and epithelial debris for microbiological or cellular examination. - - + + @@ -19606,23 +19626,16 @@ exudate and epithelial debris for microbiological or cellular examination. - - + + - - - - - - - + labeled RNA extract a labeled specimen that is the output of a labeling process and has grain labeled RNA to be able to detect RNA in future experiments. - Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. -Added duirng Mar 1, 2010 dev call + Need to find out if we consider labeled nucleotides still nucleotides. It is after consulting with ChEBI group. Added duirng Mar 1, 2010 dev call Group: OBI group Group: OBI group labeled RNA extract @@ -19636,6 +19649,7 @@ Added duirng Mar 1, 2010 dev call + @@ -19655,18 +19669,9 @@ Added duirng Mar 1, 2010 dev call - - - - - - - - - frozen specimen Frozen blood plasma @@ -20348,6 +20353,7 @@ Biochimie. 2010 Feb 18. + @@ -20367,17 +20373,9 @@ Biochimie. 2010 Feb 18. - - - - - - - - paraffin specimen liver tissue embedded in paraffin @@ -20466,19 +20464,22 @@ Biochimie. 2010 Feb 18. - + + + + + + processed specimen - A tissue sample that has been sliced and stained for a histology study. -A blood specimen that has been centrifuged to obtain the white blood cells. A specimen that has been intentionally physically modified. + A tissue sample that has been sliced and stained for a histology study. Bjoern Peters Bjoern Peters - A tissue sample that has been sliced and stained for a histology study. processed specimen @@ -20697,6 +20698,7 @@ A blood specimen that has been centrifuged to obtain the white blood cells. + @@ -20716,16 +20718,9 @@ A blood specimen that has been centrifuged to obtain the white blood cells. - - - - - - - lyophilized specimen freezing dried DNA @@ -20899,7 +20894,6 @@ In the examples above, a reagent is an operational component of a device, but th - fresh specimen a liver freshly removed from a rat @@ -21099,27 +21093,31 @@ In the examples above, a reagent is an operational component of a device, but th - - - - - - - - - + + + + + + + + + - - + + + + + + + - - - - - - + + + + + + - agar stab specimen a specimen that is output of a process that cell culture inoculated into agar for long term storage. @@ -21845,31 +21843,17 @@ JZ: based on textual definition of edited document, it can be defined as N&S - - - - - - - - - - - - - - - + - - + + nucleic acid extract An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen. - PERSON: Jie Zheng + Person: Jie Zheng UPenn Group nucleic acid extract @@ -25339,10 +25323,10 @@ JZ: based on textual definition of edited document, it can be defined as N&S - - + + @@ -25358,25 +25342,18 @@ JZ: based on textual definition of edited document, it can be defined as N&S - - + + - - - - - - - + labeled nucleic acid extract a labeled specimen that is the output of a labeling process and has grain labeled nucleic acid for detection of the nucleic acid in future experiments. Person: Jie Zheng labeled extract MO_221 labeledExtract - labeled extract labeled nucleic acid extract @@ -35275,26 +35252,24 @@ http://svitsrv25.epfl.ch/R-doc/library/qvalue.html - - - - - - - - - - - - - - cell specimen + + + + + + + + + + + + cell specimen A specimen primarily composed of a cell or cells collected from a multicellular organism or a cell culture. - Discussed on obi call Jan 23, 2017. To improve cell specimen that include single cell specimen. Details see tracker: https://sourceforge.net/p/obi/obi-terms/828/ + Discussed on obi call Jan 23, 2017. To improve cell specimen that include single cell specimen. Details see tracker: https://sourceforge.net/p/obi/obi-terms/828 PERSON: Chris Stoeckert, Jie Zheng, Alexander Diehl MO_612 cell - cell specimen + cell specimen @@ -35370,27 +35345,31 @@ http://svitsrv25.epfl.ch/R-doc/library/qvalue.html - - + + - - - - - - - + + + + + + + + + + + + - + - - specimen with known storage state + specimen with known storage state A specimen for which it is known whether it has been subjected to storage of a specified type. PERSON: Chris Stoeckert, Jie Zheng MO_95 BiosourceType - specimen with known storage state + specimen with known storage state @@ -35633,31 +35612,38 @@ http://svitsrv25.epfl.ch/R-doc/library/qvalue.html + - - - - - + - - - - + + + + + + + + + + + + + + + - A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm). PERSON: Chris Stoeckert, Jie Zheng - tissue specimen + tissue specimen MO_954 organism_part - specimen from organism + specimen from organism @@ -36548,46 +36534,50 @@ http://svitsrv25.epfl.ch/R-doc/library/qvalue.html - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + - - specimen with pre- or post-mortem status + specimen with pre- or post-mortem status A specimen that has been established to be taken from a live (pre-mortem) or dead (post-mortem) organism. organizational term, used in description of specimen that is created from known pre- or post-mortem status PERSON: Chris Stoeckert, Jie Zheng MO_84 OrganismStatus - specimen with pre- or post-mortem status + specimen with pre- or post-mortem status @@ -55098,14 +55088,20 @@ Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries. + + + + + + Gravina, Michael T., Jenny H. Lin, and Stuart S. Levine. "Lane-by-lane sequencing using Illumina's Genome Analyzer II." BioTechniques 54.5 (2013): 265-269. PMID: 23662897 An Illumina Genome Analyzer II which is manufactured by the Illumina corporation. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology. The Genome Analyzer IIx is the most widely adopted next-generation sequencing platform and proven and published across the broadest range of research applications. PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng, Alan Ruttenberg + Genome Analyzer IIx Illumina GA IIx - Illumina Genome Analyzer IIx ENCODE group - Genome Analyzer IIx + Illumina Genome Analyzer IIx @@ -55113,7 +55109,7 @@ Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries. - + @@ -55134,7 +55130,7 @@ Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries. - + @@ -55166,9 +55162,9 @@ Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries. A DNA sequencer which is manufactured by the Illumina corporation. Built upon sequencing by synthesis technology, the machine provides an end-to-end solution (cluster generation, amplification, sequencing, and data analysis) in a single machine. PERSON: Venkat Malladi, Chris Stoeckert, Jie Zheng - Illumina MiSeq + MiSeq http://res.illumina.com/documents/products/datasheets/datasheet_miseq.pdf - MiSeq + Illumina MiSeq @@ -56018,7 +56014,7 @@ Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries. - + @@ -56027,9 +56023,9 @@ Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries. A DNA sequencer which is a desktop sequencer ideal for smaller-scale studies manufactured by the Illumina corporation. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology. Person: Venkat Malladi, Chris Stoeckert, Jie Zheng - Illumina NextSeq 500 + NextSeq 500 http://systems.illumina.com/systems/nextseq-sequencer.html - NextSeq 500 + Illumina NextSeq 500 @@ -56037,7 +56033,7 @@ Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries. - + @@ -56140,12 +56136,18 @@ Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries. + + + + + + An Illumina Genome Analyzer II which is manufactured by the Illumina corporation. It supports sequencing of single, long or short insert paired end clone libraries relying on sequencing by synthesis technology. The Genome Analyzer IIe makes industry-leading next-generation sequencing technology accessible to more laboratories. Person: Venkat Malladi, Chris Stoeckert, Jie Zheng + Genome Analyzer IIe Illumina GA IIe - Illumina Genome Analyzer IIe http://res.illumina.com/documents/products/datasheets/datasheet_genome_analyzer_iie.pdf - Genome Analyzer IIe + Illumina Genome Analyzer IIe @@ -56482,7 +56484,7 @@ Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries. - + Kasinathan et al., (February 2014). "High-resolution mapping of transcription factor binding sites on natitve chromatin." Nat Methods 11(2):203-9. doi: 10.1038/nmeth.2766. An assay to capture the location of open chromatin, DNA-binding proteins, individual nucleosomes and chromatin compaction at nucleotide resolution by Tn5 transposase insertion. Chris Stoeckert @@ -56685,7 +56687,7 @@ Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries. - + @@ -56705,7 +56707,7 @@ Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries. - + @@ -59063,7 +59065,7 @@ https://www.doi.org/ - + @@ -59073,13 +59075,13 @@ https://www.doi.org/ - - H&E-stained fixed tissue slide specimen + + H&E-stained fixed tissue slide specimen A fixed tissue slide specimen that is the output of H&E slide staining. - Chris Stoeckert, Ned Haubein - OBIB, OBI - H&E-stained fixed tissue slide specimen + Chris Stoeckert, Ned Haubein + OBIB, OBI + H&E-stained fixed tissue slide specimen @@ -59087,7 +59089,7 @@ https://www.doi.org/ - + @@ -59097,14 +59099,13 @@ https://www.doi.org/ - - IHC-stained fixed tissue slide specimen + + IHC-stained fixed tissue slide specimen A fixed tissue slide specimen that is the output of immunohistochemistry slide staining. - Chris Stoeckert, Ned Haubein - immunohistochemistry slide specimen - OBIB, OBI - IHC-stained fixed tissue slide specimen + Chris Stoeckert, Ned Haubein + OBIB, OBI + IHC-stained fixed tissue slide specimen @@ -59118,7 +59119,7 @@ https://www.doi.org/ Requested by Sirarat Sarntivijai (EBI). Details see tracker: https://sourceforge.net/p/obi/obi-terms/828/ PERSON: Jie Zheng, Alexander Diehl PERSON: Jie Zheng, Alexander Diehl - single cell specimen + single cell specimen @@ -59127,6 +59128,12 @@ https://www.doi.org/ + + + + + + Illumina Genome Analyzer A DNA sequencer manufactured by Solexa as one of its first sequencer lines, launched in 2006, and capable of sequencing 1 gigabase (Gb) of data in a single run. @@ -59141,7 +59148,13 @@ https://www.doi.org/ - + + + + + + + Illumina HiSeq X Ten A DNA sequencer that consists of a set of 10 HiSeq X Sequencing Systems. @@ -63767,9 +63780,9 @@ https://www.doi.org/ + - @@ -63780,15 +63793,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -63807,9 +63815,9 @@ https://www.doi.org/ + - @@ -63820,15 +63828,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -63847,9 +63850,9 @@ https://www.doi.org/ + - @@ -63860,15 +63863,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -63887,9 +63885,9 @@ https://www.doi.org/ + - @@ -63900,15 +63898,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -63928,9 +63921,9 @@ https://www.doi.org/ + - @@ -63941,15 +63934,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -63969,9 +63957,9 @@ https://www.doi.org/ + - @@ -63982,15 +63970,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64009,9 +63992,9 @@ https://www.doi.org/ + - @@ -64022,15 +64005,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64049,9 +64027,9 @@ https://www.doi.org/ + - @@ -64062,15 +64040,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64089,9 +64062,9 @@ https://www.doi.org/ + - @@ -64102,15 +64075,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64129,9 +64097,9 @@ https://www.doi.org/ + - @@ -64142,15 +64110,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64169,9 +64132,9 @@ https://www.doi.org/ + - @@ -64182,15 +64145,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64209,9 +64167,9 @@ https://www.doi.org/ + - @@ -64232,15 +64190,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64260,9 +64213,9 @@ https://www.doi.org/ + - @@ -64273,15 +64226,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64300,9 +64248,9 @@ https://www.doi.org/ + - @@ -64323,15 +64271,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64350,9 +64293,9 @@ https://www.doi.org/ + - @@ -64363,15 +64306,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64390,9 +64328,9 @@ https://www.doi.org/ + - @@ -64403,15 +64341,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64430,9 +64363,9 @@ https://www.doi.org/ + - @@ -64453,15 +64386,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64480,9 +64408,9 @@ https://www.doi.org/ + - @@ -64493,15 +64421,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64520,9 +64443,9 @@ https://www.doi.org/ + - @@ -64543,15 +64466,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64570,9 +64488,9 @@ https://www.doi.org/ + - @@ -64583,15 +64501,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64610,9 +64523,9 @@ https://www.doi.org/ + - @@ -64633,15 +64546,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64660,9 +64568,9 @@ https://www.doi.org/ + - @@ -64683,15 +64591,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64711,9 +64614,9 @@ https://www.doi.org/ + - @@ -64734,15 +64637,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64761,9 +64659,9 @@ https://www.doi.org/ + - @@ -64784,15 +64682,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64812,9 +64705,9 @@ https://www.doi.org/ + - @@ -64835,15 +64728,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64862,9 +64750,9 @@ https://www.doi.org/ + - @@ -64885,15 +64773,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64912,9 +64795,9 @@ https://www.doi.org/ + - @@ -64935,15 +64818,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -64963,9 +64841,9 @@ https://www.doi.org/ + - @@ -64986,15 +64864,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65013,9 +64886,9 @@ https://www.doi.org/ + - @@ -65036,15 +64909,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65063,9 +64931,9 @@ https://www.doi.org/ + - @@ -65086,15 +64954,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65113,9 +64976,9 @@ https://www.doi.org/ + - @@ -65126,15 +64989,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65153,9 +65011,9 @@ https://www.doi.org/ + - @@ -65176,15 +65034,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65204,9 +65057,9 @@ https://www.doi.org/ + - @@ -65227,15 +65080,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65254,9 +65102,9 @@ https://www.doi.org/ + - @@ -65277,15 +65125,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65304,9 +65147,9 @@ https://www.doi.org/ + - @@ -65327,15 +65170,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65354,9 +65192,9 @@ https://www.doi.org/ + - @@ -65377,15 +65215,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65405,9 +65238,9 @@ https://www.doi.org/ + - @@ -65428,15 +65261,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65456,9 +65284,9 @@ https://www.doi.org/ + - @@ -65479,15 +65307,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65506,9 +65329,9 @@ https://www.doi.org/ + - @@ -65529,15 +65352,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65557,9 +65375,9 @@ https://www.doi.org/ + - @@ -65580,15 +65398,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65607,9 +65420,9 @@ https://www.doi.org/ + - @@ -65630,15 +65443,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65657,9 +65465,9 @@ https://www.doi.org/ + - @@ -65680,15 +65488,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65707,9 +65510,9 @@ https://www.doi.org/ + - @@ -65730,15 +65533,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65757,9 +65555,9 @@ https://www.doi.org/ + - @@ -65780,15 +65578,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65807,9 +65600,9 @@ https://www.doi.org/ + - @@ -65830,15 +65623,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65857,9 +65645,9 @@ https://www.doi.org/ + - @@ -65880,15 +65668,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65907,9 +65690,9 @@ https://www.doi.org/ + - @@ -65930,15 +65713,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -65957,9 +65735,9 @@ https://www.doi.org/ + - @@ -65980,15 +65758,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -66007,9 +65780,9 @@ https://www.doi.org/ + - @@ -66030,15 +65803,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -66057,9 +65825,9 @@ https://www.doi.org/ + - @@ -66080,15 +65848,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -66107,9 +65870,9 @@ https://www.doi.org/ + - @@ -66130,15 +65893,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -66157,9 +65915,9 @@ https://www.doi.org/ + - @@ -66180,15 +65938,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -66207,9 +65960,9 @@ https://www.doi.org/ + - @@ -66230,15 +65983,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -66257,9 +66005,9 @@ https://www.doi.org/ + - @@ -66280,15 +66028,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -66307,9 +66050,9 @@ https://www.doi.org/ + - @@ -66330,15 +66073,10 @@ https://www.doi.org/ - - - - - - - - - + + + + @@ -66663,13 +66401,11 @@ https://www.doi.org/ - polyA depleted RNA extract A RNA extract that is the output of an extraction process in which RNA molecules lacking poly A tails at thier 3' ends are purified. Mark A. Miller, based on http://purl.obolibrary.org/obo/OBI_0000869 PERSON: Chris Stoeckert PERSON: Jie Zheng UPenn Group - 2018-05-11T16:35:11Z polyA depleted RNA extract @@ -67096,12 +66832,16 @@ https://www.doi.org/ - - - - + + + + + + + + + - swab specimen A specimen that is stored on a swab as the output of a collecting specimen with swab process. @@ -67160,34 +66900,25 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -67206,34 +66937,25 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -67252,34 +66974,25 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -67298,34 +67011,25 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -67344,34 +67048,25 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -67390,34 +67085,25 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -67436,34 +67122,25 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -67482,34 +67159,25 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -67528,34 +67196,25 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -67574,34 +67233,25 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -67621,34 +67271,25 @@ https://www.doi.org/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -67901,7 +67542,7 @@ https://www.doi.org/ An extract of RNA which is produced through rRNA (ribosomal RNA) depletion (the removal of highly abundant rRNA species). Dan Berrios - https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-4585-1 + https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-018-4585-1 ribosomal RNA-depleted RNA extract @@ -67950,7 +67591,7 @@ https://www.doi.org/ - + @@ -69022,14 +68663,18 @@ https://www.doi.org/ - - - - - 1 - - - + + + + + + + 1 + + + + + A specimen composed of an individual organism to be studied in an investigation. Person: Jie Zheng EFO_0000542 individual @@ -70326,7 +69971,13 @@ https://www.doi.org/ - + + + + + + + A specimen used in a blood meal assay to determine what is the source of blood ingested by a mosquito. A specimen of the blood ingested by an arthropod. @@ -72249,10 +71900,10 @@ JZ (3-30-20): discussed on the OBI call. Since the REO was never actually regist + - @@ -72265,15 +71916,10 @@ JZ (3-30-20): discussed on the OBI call. Since the REO was never actually regist - - - - - - - - - + + + + A sputum specimen that is collected from an organism following its inhalation of a nebulized salt solution. John Judkins @@ -72820,8 +72466,8 @@ b) that the amount of analyte/measurand detected is over some predetermined thre A blood plasma specimen that is the output of some platelet-poor plasma preparation and is the portion of plasma that contains fewer than 10,000 platelets per microliter. - PERSON: Matthew Diller - platelet-poor plasma specimen + PERSON: Matthew Diller + platelet-poor plasma specimen @@ -72866,37 +72512,28 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + - - - - - - - - - + + + + - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + A specimen that is collected with a suctioning tube from the trachea. Asiyah Yu Lin ORCID:0000-0003-2620-0345 @@ -72913,34 +72550,25 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -72958,34 +72586,25 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -73005,34 +72624,25 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -73051,34 +72661,25 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -73096,7 +72697,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + @@ -73128,34 +72729,25 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -75061,10 +74653,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + - @@ -75077,15 +74669,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + A specimen that derives from a biofilm that forms on the inner surface of an endotracheal tube while the tube is in the trachea. The specimen is collected upon removal of the tube from the trachea. John Judkins ORCID:0000-0001-6595-0902 @@ -75098,10 +74685,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + - @@ -75114,15 +74701,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + A specimen that derives from a biofilm that forms on the inner surface of an endotracheal tube while the tube is in the trachea. The specimen is collected by suction without removing the tube. John Judkins ORCID:0000-0001-6595-0902 @@ -77102,10 +76684,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + - @@ -77118,15 +76700,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + A blood specimen that is located in a vacutainer. John Judkins @@ -77140,10 +76717,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + - @@ -77156,15 +76733,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + A blood specimen that is located on a filter paper. Chris Stoeckert @@ -84103,9 +83675,9 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + - @@ -84116,15 +83688,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + @@ -84247,7 +83814,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + @@ -84271,7 +83838,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + @@ -84286,7 +83853,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre https://www.illumina.com/systems/sequencing-platforms/nextseq.html https://github.com/obi-ontology/obi/issues/1546 gEAR - NextSeq 550 + Illumina NextSeq 550 @@ -84737,10 +84304,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + - @@ -84753,15 +84320,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + A processed specimen that is extracted from whole blood using gradient centrifugation that separates the blood into a layer of peripheral blood mononuclear cells under the top layer of plasma. It contains lymphocytes, monocytes or macrophages that are critical components in the immune system. Chris Stoeckert @@ -86941,10 +86503,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + - @@ -86967,15 +86529,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + A specimen that is derived from a portion of lymph collected from an organism. John Judkins ORCID:0000-0001-6595-0902 @@ -86988,10 +86545,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + - @@ -87014,15 +86571,10 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - + + + + A specimen that is derived from part of a digestive tract. John Judkins ORCID:0000-0001-6595-0902 @@ -90269,34 +89821,25 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -90540,7 +90083,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + @@ -91626,23 +91169,27 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - + + + + + + + + + + + + + + + albumin-free serum A blood serum specimen that contains no albumin. Sebastian Duesing https://github.com/obi-ontology/obi/issues/493 Philippe Rocca-Serra - albumin-free serum + albumin-free serum @@ -92003,7 +91550,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + @@ -92026,7 +91573,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + @@ -92052,7 +91599,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + @@ -92076,34 +91623,25 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + @@ -92118,6 +91656,112 @@ b) that the amount of analyte/measurand detected is over some predetermined thre + + + + + + + + + + + https://www.illumina.com/content/dam/illumina-support/documents//products/datasheets/datasheet_hiseq_systems.pdf + + A DNA Sequencer manufactured and/or marketed by Illumina and branded with the word HiSeq. + This class represents a series of instruments with various model names. There are several models in this series, including one that was simply called “HiSeq” as the model name. GENEPIO:0100110 ‘Illumina HiSeq’ may refer to a model, not the series. OBI may not have classes for all of the instruments in this series. + PERSON: Mark Andrew Miller + HiSeq series + PERSON: Mark Andrew Miller + https://github.com/obi-ontology/obi/issues/1825 + Alicia Clum + Illumina HiSeq Series Instrument + + + + + + + + + + + + + + + https://www.cd-genomics.com/blog/nextseq/ + + A DNA Sequencer manufactured and/or marketed by Illumina and branded with the word NextSeq. + This class represents a series of instruments with various model names. There are several models in this series. OBI may not have classes for all of the instruments in this series. It is unclear whether GENEPIO:0100126 ’Illumina NextSeq’ refers to the series or a model. + PERSON: Mark Andrew Miller + NextSeq series + PERSON: Mark Andrew Miller + https://github.com/obi-ontology/obi/issues/1825 + Alicia Clum + Illumina NextSeq Series Instrument + + + + + + + + + + + + + + + + A DNA Sequencer manufactured and/or marketed by Illumina and branded with the word NovaSeq. + This class represents a series of instruments with various model names. There are several models in this series. OBI may not have classes for all of the instruments in this series. It is unclear whether GENEPIO:0100122 ‘Illumina NovaSeq’ refers to the series or to a model. + PERSON: Mark Andrew Miller + NovaSeq series + PERSON: Mark Andrew Miller + https://github.com/obi-ontology/obi/issues/1825 + Alicia Clum + Illumina NovaSeq Series Instrument + + + + + + + + + chromatin accessibility assay + An assay that determines which regions of a DNA molecule are in the form of euchromatin and thus able to make direct physical contact with (i.e. are accessible to) other molecules such as RNA polymerase, transcription factors, etc. + Bjoern Peters + Michelle Giglio + Sebastian Duesing + Michelle Giglio + https://github.com/obi-ontology/obi/issues/1813 + Jennifer Jou + chromatin accessibility assay + + + + + + + + + m6A-MTase sequencing assay + https://pubmed.ncbi.nlm.nih.gov/32587015/ + A DNA methylation profiling assay in which chromatin stencils are created by treating nuclei with m6A methyltransferase (MTase) and then sequenced using single-molecule circular consensus sequencing to identify regions of accessible DNA at nucleotide resolution. + Jennifer Jou + Sebastian Duesing + Fiber-seq + Jennifer Jou + https://github.com/obi-ontology/obi/issues/1813 + Jennifer Jou + m6A-MTase sequencing assay + + + + @@ -92207,18 +91851,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - - - - - - + @@ -92235,17 +91868,17 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - blood plasma specimen - PMID: 18217225.Sex Transm Dis. 2008 Jan;35(1):55-60. Review.Human immunodeficiency virus viral load in blood plasma and semen: review and implications of empirical findings. + blood plasma specimen + PMID: 18217225.Sex Transm Dis. 2008 Jan;35(1):55-60. Review.Human immunodeficiency virus viral load in blood plasma and semen: review and implications of empirical findings. a material entity which corresponds to the liquid component of blood, in which the blood cells are suspended. - 03/21/2010: BP, blood plasma is defined as the output of certain separation processes, so this is in the domain of OBI, not FMA. - PERSON: Maura Gasparetto - PERSON: Melanie Courtot + 03/21/2010: BP, blood plasma is defined as the output of certain separation processes, so this is in the domain of OBI, not FMA. + PERSON: Maura Gasparetto + PERSON: Melanie Courtot PERSON: Philippe Rocca-Serra - plasma - WEB: http://en.wikipedia.org/wiki/Blood_plasma - blood plasma specimen + plasma + WEB: http://en.wikipedia.org/wiki/Blood_plasma + blood plasma specimen @@ -92253,7 +91886,7 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - + @@ -92276,21 +91909,15 @@ b) that the amount of analyte/measurand detected is over some predetermined thre - - - - - - - blood serum specimen - PMID: 18229666.Adv Med Sci. 2007;52 Suppl 1:204-6.Antioxidant activity of blood serum and saliva in patients with periodontal disease treated due to epilepsy. + blood serum specimen + PMID: 18229666.Adv Med Sci. 2007;52 Suppl 1:204-6.Antioxidant activity of blood serum and saliva in patients with periodontal disease treated due to epilepsy. A material entity which derives from blood and corresponds to blood plasma without fibrinogen or the other clotting factors. - PERSON: Maura Gasparetto - PERSON: Melanie Courtot + PERSON: Maura Gasparetto + PERSON: Melanie Courtot PERSON: Philippe Rocca-Serra - WEB: http://en.wikipedia.org/wiki/Blood_plasma - blood serum specimen + WEB: http://en.wikipedia.org/wiki/Blood_plasma + blood serum specimen @@ -92430,10 +92057,9 @@ This issue is outside the scope of OBI. specimen - Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen. + Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen; collecting a stone from a site. - A material entity that has the specimen role. - Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation. + A material entity that is collected for potential use as an input upon which measurements or observations are performed. PERSON: James Malone PERSON: Philippe Rocca-Serra GROUP: OBI Biomaterial Branch @@ -92706,27 +92332,37 @@ Thyroidectomy during laryngectomy for advanced laryngeal carcinoma--whole organ - - - - - - - - - - - - - - bronchial alveolar lavage - solution containing lung derived T cells, eosinophils, and TNFa. + + + + + + + + + + + + + + + + + + + + + + + + bronchial alveolar lavage + solution containing lung derived T cells, eosinophils, and TNFa. Group of biomaterials present in the bronchial aveolar space of an organism which are collected through lavage including the reagents used to for the lavage process, organisms, cells, and cellular secretions present in the bronchial aveolar space. - PERSON: Bjoern Peters - BAL - GROUP: IEDB - bronchial alveolar lavage + PERSON: Bjoern Peters + BAL + GROUP: IEDB + bronchial alveolar lavage @@ -96797,14 +96433,13 @@ determinations of compounds. - - pool of specimens + pool of specimens A pool of specimens is a mixture of a population of samples which have been gathered from one or more sample populations, obtained by the physical process of mixing individual specimens, e.g. mixing the DNA collected from the individual fish. - check with advisors as to how to represent multiple instances of any class? a set of specimens which have been gathered from one or more sample_populations, obtained by the physical process of mixing individual specimens, e.g. mixing the DNA collected from the individual fish + check with advisors as to how to represent multiple instances of any class? a set of specimens which have been gathered from one or more sample_populations, obtained by the physical process of mixing individual specimens, e.g. mixing the DNA collected from the individual fish PERSON: Jennifer Fostel GROUP: CEBS - pool of specimens + pool of specimens @@ -103395,16 +103030,16 @@ Possible ecological risks of transgenic organism release when transgenes affect - whole mount tissue + whole mount tissue A whole organism preparation resulting from a histological preparation known as whole mount preparation where the whole specimen is mounted or spread on the microscope (glass) slide - PERSON: Helen Parkinson + PERSON: Helen Parkinson PERSON: Philippe Rocca-Serra - whole mount sample - GROUP: OBI - PRS:22-02-2008: indicates the need to create a protocol application and distinguish it from this entity - PRS:22-02-2008: is a material which has output_role during whole mount preparation protocol-application - whole mount tissue + whole mount sample + GROUP: OBI + PRS:22-02-2008: indicates the need to create a protocol application and distinguish it from this entity + PRS:22-02-2008: is a material which has output_role during whole mount preparation protocol-application + whole mount tissue @@ -104234,29 +103869,33 @@ Possible ecological risks of transgenic organism release when transgenes affect - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + lymph node cell specimen A cell specimen comprised of a mixed population of cells obtained by processing whole lymph node into individual cells, typically performed using a sieve. This population includes T cells, B cells, macrophages, and other cell types. - IEDB - IEDB - lymph node cell specimen + IEDB + IEDB + lymph node cell specimen @@ -105205,29 +104844,33 @@ MHB 3-5-13: Need to review axiom on this class in light of clarification that it - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + + + + + + + + splenocyte specimen A cell specimen comprised of a mixed cell population obtained by processing whole spleen into individual cells, typically performed using a sieve or blender. This population includes T cells, B cells, macrophages, and other cell types. - IEDB - IEDB - splenocyte specimen + IEDB + IEDB + splenocyte specimen @@ -107119,14 +106762,12 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 FFPE specimen - Many of today’s researchers prefer to use Formalin-Fixed Paraffin-Embedded samples of tissues for their IHC, histological or in-situ genomic analyses. Professionally fixed and embedded FFPE samples and the biomolecules they contain are reasonably stable at ambient temperatures. - --based on https://lab-ally.com/histopathology-resources/ffpe-samples/ + Many of today’s researchers prefer to use Formalin-Fixed Paraffin-Embedded samples of tissues for their IHC, histological or in-situ genomic analyses. Professionally fixed and embedded FFPE samples and the biomolecules they contain are reasonably stable at ambient temperatures. -based on https://lab-ally.com/histopathology-resources/ffpe-samples/ A specimen that has been fixed in formalin and embedded in paraffin. MIABIS formalin-fixed paraffin-embeded specimen - - + https://www.biochain.com/general/what-is-ffpe-tissue/ + https://github.com/obi-ontology/obi/issues/1019 FFPE specimen @@ -107138,9 +106779,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107161,15 +106802,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107189,9 +106825,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107212,15 +106848,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107240,9 +106871,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107253,15 +106884,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107281,9 +106907,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107304,15 +106930,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107332,9 +106953,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107355,15 +106976,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107383,9 +106999,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107406,15 +107022,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107434,9 +107045,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107457,15 +107068,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107485,9 +107091,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107508,15 +107114,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107536,9 +107137,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107549,15 +107150,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107577,9 +107173,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107590,15 +107186,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107618,9 +107209,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107641,15 +107232,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107669,9 +107255,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107682,15 +107268,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107710,9 +107291,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107723,15 +107304,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107751,9 +107327,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107764,15 +107340,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107792,9 +107363,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107805,15 +107376,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107833,9 +107399,9 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - @@ -107846,15 +107412,10 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 - - - - - - - - - + + + + @@ -107871,37 +107432,28 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - - - - - - - - - + + + + - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + A specimen that is derived from some erythrocytes Christian Stoeckert ORCID:0000-0002-5714-991X @@ -107916,37 +107468,28 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - - - - - - - - - + + + + - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + A specimen that is derived from some reticulocytes Christian Stoeckert ORCID:0000-0002-5714-991X @@ -107961,37 +107504,28 @@ The content of that report on the IEDB website is here: http://iedb.org/refId/10 + - - - - - - - - - + + + + - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + + + A specimen that is derived from some leukocytes Christian Stoeckert ORCID:0000-0002-5714-991X @@ -134166,6 +133700,12 @@ realizes some 'host of immune response role' + + + + + + diff --git a/views/obi.obo b/views/obi.obo index 161f0f10..0b74ff38 100644 --- a/views/obi.obo +++ b/views/obi.obo @@ -1,6 +1,6 @@ format-version: 1.2 -data-version: 2024-10-25 -date: 25:10:2024 12:39 +data-version: 2024-12-05 +date: 05:12:2024 12:48 synonymtypedef: OMO:0003000 "abbreviation" synonymtypedef: OMO:0003001 "ambiguous synonym" synonymtypedef: OMO:0003002 "dubious synonym" @@ -80,7 +80,7 @@ property_value: http://purl.org/dc/elements/1.1/subject "An ontology for the ann property_value: http://purl.org/dc/terms/license "http://creativecommons.org/licenses/by/4.0/" xsd:string property_value: http://purl.org/dc/terms/title "Ontology for Biomedical Investigations" xsd:string property_value: IAO:0000589 "Ontology for Biomedical Investigations" xsd:string -property_value: owl:versionInfo "2024-10-25" xsd:string +property_value: owl:versionInfo "2024-12-05" xsd:string [Term] id: BFO:0000001 @@ -3854,7 +3854,7 @@ is_a: OBI:0000250 ! dye role [Term] id: OBI:0000112 name: specimen role -def: "a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation" [] +def: "A role borne by a material entity that is obtained during a specimen collection process and that can be realized by performing measurements or observations on the specimen." [] is_a: BFO:0000023 ! role [Term] @@ -4793,6 +4793,7 @@ is_a: BFO:0000023 ! role id: OBI:0000418 name: measuring glucose concentration in blood serum assay def: "An assay that determines the concentration of glucose molecules in a blood serum sample" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] @@ -6170,7 +6171,7 @@ is_a: IAO:0000033 ! directive information entity [Term] id: OBI:0000659 name: specimen collection process -def: "A planned process with the objective of collecting a specimen." [] +def: "A planned process with the objective to obtain a material entity for potential use as an input upon which measurements or observations are performed." [] synonym: "specimen collection" EXACT [] is_a: OBI:0000011 ! planned process @@ -6314,7 +6315,7 @@ is_obsolete: true [Term] id: OBI:0000684 name: specimen collection objective -def: "A objective specification to obtain a material entity for potential use as an input during an investigation." [] +def: "A objective specification that is fulfilled by obtaining a material entity for potential use as an input upon which measurements or observations are performed." [] is_a: IAO:0000005 ! objective specification [Term] @@ -6554,7 +6555,7 @@ is_a: OBI:1110092 ! adjuvant role id: OBI:0000721 name: glucose tolerance test def: "An assay that measures glucose clearance from blood over time by repeated glucose measurement in blood serum or plasma after the administration of a glucose bolus in-vivo. This assay can be used to evaluate the severity of insulin resistance or the efficiency of glucose clearance." [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:0000722 @@ -6964,7 +6965,7 @@ id: OBI:0000820 name: activated partial thromboplastin time assay def: "An assay that evaluates blood coagulation by measuring the time required for the appearance of fibrin strands following the mixing blood or plasma with phospholipid platelet substitute (e.g., crude cephalins, soybean phosphatides). It is a test of the intrinsic pathway (factors VIII, IX, XI, and XII) and the common pathway (fibrinogen, prothrombin, factors V and X) of blood coaguation . It is used as a screening test and to monitor heparin therapy." [] synonym: "aPTT assay" EXACT [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:0000821 @@ -7244,13 +7245,13 @@ name: serum neutralization of viral infectivity assay def: "An analyte assay that measures virus-neutralizing abilities of different sera. Different dilutions of serum are mixed with virus and used to infect cells. At the lower dilutions, antibodies will block infection, but at higher dilutions, there will be too few antibodies to have an effect.The neutralization titer is expressed as the reciprocal of the highest dilution at which virus infection is blocked." [] synonym: "influenza neutralization assay" EXACT [] is_a: OBI:0000443 ! analyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:0000873 name: pre-mortem specimen def: "a specimen that was taken from a live organism" [] is_a: OBI:0001506 ! specimen with pre- or post-mortem status -disjoint_from: OBI:0000902 ! post mortem specimen [Term] id: OBI:0000874 @@ -7426,8 +7427,8 @@ is_a: OBI:0001143 ! labeled nucleic acid extract [Term] id: OBI:0000909 name: cloacal specimen -def: "A specimen obtained by inserting a swab deeply into the vent of the cloaca of\nan organism and vigorously swabbing the wall. The swab should be deeply\nstained with fecal material and is then placed in transport medium." [] -is_a: OBI:0100051 ! specimen +def: "A specimen obtained by inserting a swab deeply into the vent of the cloaca of an organism and vigorously swabbing the wall. The swab should be deeply stained with fecal material and is then placed in transport medium." [] +is_a: OBI:0001479 ! specimen from organism [Term] id: OBI:0000910 @@ -7459,8 +7460,8 @@ is_a: OBI:0000070 ! assay [Term] id: OBI:0000914 name: nasopharyngeal aspirate specimen -def: "A speciemn which derives from nasopharyngeal mucosa after\naspiration." [] -is_a: OBI:0100051 ! specimen +def: "A specimen which derives from nasopharyngeal mucosa after aspiration." [] +is_a: OBI:0001479 ! specimen from organism [Term] id: OBI:0000915 @@ -7478,7 +7479,8 @@ is_a: OBI:0001977 ! cytometry assay [Term] id: OBI:0000917 name: nasal swab specimen -def: "A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of\nexudate and epithelial debris for microbiological or cellular examination." [] +def: "A specimen obtained using a cotton swab on a stick, passed up the nostril to obtain a sample of exudate and epithelial debris for microbiological or cellular examination." [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] @@ -7515,10 +7517,6 @@ id: OBI:0000922 name: frozen specimen def: "A specimen that has been frozen in order to store it." [] is_a: OBI:0001472 ! specimen with known storage state -disjoint_from: OBI:0000950 ! paraffin specimen -disjoint_from: OBI:0000965 ! lyophilized specimen -disjoint_from: OBI:0000971 ! fresh specimen -disjoint_from: OBI:0000981 ! agar stab specimen [Term] id: OBI:0000923 @@ -7697,9 +7695,6 @@ id: OBI:0000950 name: paraffin specimen def: "a specimen that is output of a paraffin storage process in which specimen is embedded in paraffin" [] is_a: OBI:0001472 ! specimen with known storage state -disjoint_from: OBI:0000965 ! lyophilized specimen -disjoint_from: OBI:0000971 ! fresh specimen -disjoint_from: OBI:0000981 ! agar stab specimen [Term] id: OBI:0000951 @@ -7717,7 +7712,6 @@ is_a: OBI:0600007 ! administering substance in vivo id: OBI:0000953 name: processed specimen def: "A specimen that has been intentionally physically modified." [] -comment: A tissue sample that has been sliced and stained for a histology study. is_a: OBI:0000047 ! processed material is_a: OBI:0100051 ! specimen @@ -7788,8 +7782,6 @@ id: OBI:0000965 name: lyophilized specimen def: "a specimen that is output of a lyophilization storage process in which specimen is lyophilized for storage." [] is_a: OBI:0001472 ! specimen with known storage state -disjoint_from: OBI:0000971 ! fresh specimen -disjoint_from: OBI:0000981 ! agar stab specimen [Term] id: OBI:0000966 @@ -7829,7 +7821,6 @@ id: OBI:0000971 name: fresh specimen def: "a specimen that is output of a specimen creation process used for an investigation without storage." [] is_a: OBI:0001472 ! specimen with known storage state -disjoint_from: OBI:0000981 ! agar stab specimen [Term] id: OBI:0000972 @@ -8054,7 +8045,6 @@ is_obsolete: true id: OBI:0001010 name: nucleic acid extract def: "An extract that is the output of an extraction process in which nucleic acid molecules are isolated from a specimen." [] -is_a: OBI:0000423 ! extract is_a: OBI:0000953 ! processed specimen [Term] @@ -11014,7 +11004,7 @@ is_a: OBI:0001484 ! assay measuring T cell epitope specific in vivo activity id: OBI:0001468 name: cell specimen def: "A specimen primarily composed of a cell or cells collected from a multicellular organism or a cell culture." [] -is_a: OBI:0100051 ! specimen +is_a: OBI:0001479 ! specimen from organism [Term] id: OBI:0001469 @@ -11266,7 +11256,7 @@ is_a: OBI:0600014 ! material component separation id: OBI:0001506 name: specimen with pre- or post-mortem status def: "A specimen that has been established to be taken from a live (pre-mortem) or dead (post-mortem) organism." [] -is_a: OBI:0100051 ! specimen +is_a: OBI:0001479 ! specimen from organism [Term] id: OBI:0001507 @@ -15089,7 +15079,7 @@ name: assay for transposase-accessible chromatin using sequencing def: "An assay to capture the location of open chromatin, DNA-binding proteins, individual nucleosomes and chromatin compaction at nucleotide resolution by Tn5 transposase insertion." [] synonym: "ATAC-seq" EXACT [] synonym: "ATAC-seq assay" EXACT [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003686 ! chromatin accessibility assay [Term] id: OBI:0002040 @@ -15727,7 +15717,6 @@ is_a: OMIABIS:0000052 ! fixed tissue slide specimen id: OBI:0002126 name: IHC-stained fixed tissue slide specimen def: "A fixed tissue slide specimen that is the output of immunohistochemistry slide staining." [] -synonym: "immunohistochemistry slide specimen" EXACT [] is_a: OMIABIS:0000052 ! fixed tissue slide specimen [Term] @@ -17810,54 +17799,63 @@ is_a: OBI:0000973 ! sequence data id: OBI:0002603 name: areolar swab specimen def: "A specimen that is collected with a swab from the surface of an areola of a breast." [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] id: OBI:0002604 name: breast swab specimen def: "A specimen that is collected with a swab from the surface of a breast." [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] id: OBI:0002605 name: cheek swab specimen def: "A specimen that is collected with a swab from the cheek portion of the inside surface of a mouth." [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] id: OBI:0002606 name: nasopharyngeal swab specimen def: "A specimen that is collected with a swab from the surface of a nasopharynx." [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] id: OBI:0002607 name: oral swab specimen def: "A specimen that is collected with a swab from the inside surface of a mouth." [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] id: OBI:0002608 name: oropharyngeal swab specimen def: "A specimen that is collected with a swab from the surface of a oropharynx." [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] id: OBI:0002609 name: rectal swab specimen def: "A specimen that is collected with a swab from the surface of a rectum." [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] id: OBI:0002610 name: tongue swab specimen def: "A specimen that is collected with a swab from the surface of a tongue." [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] id: OBI:0002611 name: vagina swab specimen def: "A specimen that is collected with a swab from the surface of a vagina." [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] @@ -17865,6 +17863,7 @@ id: OBI:0002612 name: fecal swab specimen def: "A specimen that is collected with a swab from the surface of a feces." [] synonym: "stool swab specimen" EXACT [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] @@ -18418,7 +18417,7 @@ id: OBI:0002691 name: arthropod meal of blood specimen def: "A specimen of the blood ingested by an arthropod." [] synonym: "blood meal" EXACT [] -is_a: OBI:0100051 ! specimen +is_a: OBI:0001479 ! specimen from organism [Term] id: OBI:0002692 @@ -19007,12 +19006,13 @@ id: OBI:0002778 name: tracheal aspirate specimen def: "A specimen that is collected with a suctioning tube from the trachea." [] synonym: "tracheal wash specimen" EXACT [] -is_a: OBI:0100051 ! specimen +is_a: OBI:0001479 ! specimen from organism [Term] id: OBI:0002779 name: mid-turbinate nasal swab specimen def: "A specimen that is collected with a mid-turbinate nasal swab from the turbinate area of the nasal cavity." [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] @@ -19021,7 +19021,7 @@ name: nasal aspirate specimen def: "A specimen that is collected with a suctioning tube from the nasal cavity." [] synonym: "nasal wash specimen" EXACT [] synonym: "nasopharyngeal aspirate" EXACT [] -is_a: OBI:0100051 ! specimen +is_a: OBI:0001479 ! specimen from organism [Term] id: OBI:0002781 @@ -19034,18 +19034,20 @@ is_a: OBI:0002783 ! lower respiratory tract specimen id: OBI:0002782 name: upper respiratory specimen def: "A specimen that is derived from the upper respiratory tract" [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] id: OBI:0002783 name: lower respiratory tract specimen def: "A specimen that is derived from the lower respiratory tract." [] -is_a: OBI:0100051 ! specimen +is_a: OBI:0001479 ! specimen from organism [Term] id: OBI:0002784 name: anterior nasal swab specimen def: "A specimen that is derived from the anterior nasal wall" [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] @@ -20327,14 +20329,14 @@ id: OBI:0003054 name: blood specimen in vacutainer def: "A blood specimen that is located in a vacutainer." [] synonym: "Vacutainer sample" EXACT [] -is_a: OBI:2000009 ! bodily fluid specimen +is_a: OBI:0000655 ! blood specimen [Term] id: OBI:0003055 name: blood specimen on filter paper def: "A blood specimen that is located on a filter paper." [] synonym: "Filter paper sample" EXACT [] -is_a: OBI:2000009 ! bodily fluid specimen +is_a: OBI:0000655 ! blood specimen [Term] id: OBI:0003056 @@ -21391,7 +21393,7 @@ is_a: OBI:0000070 ! assay id: OBI:0003238 name: umbilical cord blood assay def: "An assay that has an umbilical cord blood specimen as evaluant." [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:0003239 @@ -21527,7 +21529,7 @@ is_a: OBI:0003064 ! organism detection datum id: OBI:0003259 name: umbilical cord blood assay datum def: "A data item that is the specified output of an umbilical cord blood assay." [] -is_a: IAO:0000027 ! data item +is_a: OBI:0003243 ! blood assay datum [Term] id: OBI:0003260 @@ -22240,7 +22242,7 @@ is_a: OBI:0003366 ! organism diagnostic process id: OBI:0003380 name: placental blood specimen def: "A specimen that is derived from placental blood." [] -is_a: OBI:2000009 ! bodily fluid specimen +is_a: OBI:0000655 ! blood specimen [Term] id: OBI:0003381 @@ -22407,7 +22409,7 @@ id: OBI:0003415 name: peripheral blood mononuclear cell specimen def: "A processed specimen that is extracted from whole blood using gradient centrifugation that separates the blood into a layer of peripheral blood mononuclear cells under the top layer of plasma. It contains lymphocytes, monocytes or macrophages that are critical components in the immune system." [] synonym: "PBMC specimen" EXACT [] -is_a: OBI:0100051 ! specimen +is_a: OBI:0001479 ! specimen from organism [Term] id: OBI:0003416 @@ -23389,6 +23391,7 @@ name: serum anti-Epstein-Barr virus antibody level assay def: "An antigen specific antibodies assay that is meant to detect antibodies that bind to Epstein-Barr virus (EBV) antigens in a serum sample." [] synonym: "EBV" EXACT [] is_a: OBI:0002145 ! antigen specific antibodies assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:0003590 @@ -23396,6 +23399,7 @@ name: serum anti-cytomegalovirus antibody level assay def: "A CMV antibody assay that has serum as an input." [] synonym: "CMV" EXACT [] is_a: OBI:0002154 ! CMV antibody assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:0003591 @@ -23857,6 +23861,7 @@ id: OBI:0003666 name: lavage fluid specimen def: "A specimen obtained through a lavage process which includes fluid in addition to cells and/or cellular secretions." [] is_a: OBI:0000953 ! processed specimen +is_a: OBI:0001479 ! specimen from organism [Term] id: OBI:0003667 @@ -23886,6 +23891,19 @@ def: "A DNA Sequencer manufactured and/or marketed by Illumina and branded with synonym: "NovaSeq series" EXACT [] is_a: OBI:0400103 ! DNA sequencer +[Term] +id: OBI:0003686 +name: chromatin accessibility assay +def: "An assay that determines which regions of a DNA molecule are in the form of euchromatin and thus able to make direct physical contact with (i.e. are accessible to) other molecules such as RNA polymerase, transcription factors, etc." [] +is_a: OBI:0000070 ! assay + +[Term] +id: OBI:0003687 +name: m6A-MTase sequencing assay +def: "A DNA methylation profiling assay in which chromatin stencils are created by treating nuclei with m6A methyltransferase (MTase) and then sequenced using single-molecule circular consensus sequencing to identify regions of accessible DNA at nucleotide resolution." [] +synonym: "Fiber-seq" EXACT [] +is_a: OBI:0003686 ! chromatin accessibility assay + [Term] id: OBI:0005246 name: injection function @@ -23916,13 +23934,14 @@ id: OBI:0100016 name: blood plasma specimen def: "a material entity which corresponds to the liquid component of blood, in which the blood cells are suspended." [] synonym: "plasma" EXACT [] +is_a: OBI:0000655 ! blood specimen is_a: OBI:0000953 ! processed specimen [Term] id: OBI:0100017 name: blood serum specimen def: "A material entity which derives from blood and corresponds to blood plasma without fibrinogen or the other clotting factors." [] -is_a: OBI:0000953 ! processed specimen +is_a: OBI:0100016 ! blood plasma specimen [Term] id: OBI:0100026 @@ -23954,7 +23973,7 @@ is_a: OBI:0302729 ! chemical solution [Term] id: OBI:0100051 name: specimen -def: "A material entity that has the specimen role." [] +def: "A material entity that is collected for potential use as an input upon which measurements or observations are performed." [] is_a: BFO:0000040 ! material entity [Term] @@ -24037,7 +24056,7 @@ id: OBI:0100067 name: bronchial alveolar lavage def: "Group of biomaterials present in the bronchial aveolar space of an organism which are collected through lavage including the reagents used to for the lavage process, organisms, cells, and cellular secretions present in the bronchial aveolar space." [] synonym: "BAL" EXACT [] -is_a: OBI:0100051 ! specimen +is_a: OBI:0003666 ! lavage fluid specimen [Term] id: OBI:0100069 @@ -26959,7 +26978,6 @@ def: "A whole organism preparation resulting from a histological preparation kno synonym: "whole mount sample" EXACT [] is_a: OBI:0000680 ! whole organism preparation is_a: OBI:0000953 ! processed specimen -is_a: OBI:0001479 ! specimen from organism [Term] id: OBI:1000207 @@ -27927,36 +27945,39 @@ is_a: OBI:2000013 ! arterial blood specimen id: OBI:2000013 name: arterial blood specimen def: "A specimen that is derived from some arterial blood" [] -is_a: OBI:2000009 ! bodily fluid specimen +is_a: OBI:0000655 ! blood specimen [Term] id: OBI:2000014 name: venous blood specimen def: "A specimen that is derived from some venous blood" [] -is_a: OBI:2000009 ! bodily fluid specimen +is_a: OBI:0000655 ! blood specimen [Term] id: OBI:2000015 name: capillary blood specimen def: "A specimen that is derived from some capillary blood" [] -is_a: OBI:2000009 ! bodily fluid specimen +is_a: OBI:0000655 ! blood specimen [Term] id: OBI:2000016 name: erythrocyte specimen def: "A specimen that is derived from some erythrocytes" [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] id: OBI:2000017 name: reticulocyte specimen def: "A specimen that is derived from some reticulocytes" [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] id: OBI:2000018 name: leukocyte specimen def: "A specimen that is derived from some leukocytes" [] +is_a: OBI:0001479 ! specimen from organism is_a: OBI:0002599 ! swab specimen [Term] @@ -28269,24 +28290,28 @@ is_a: OBI:0000443 ! analyte assay id: OBI:2100052 name: panel5 venous blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a panel5 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] id: OBI:2100053 name: panel5 venous blood sodium assay def: "An analyte assay that measures the abundance of sodium in venous blood as part of a panel5 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] id: OBI:2100054 name: panel5 venous blood creatinine assay def: "An analyte assay that measures the abundance of creatinine in venous blood as part of a panel5 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100003 ! creatinine assay [Term] id: OBI:2100055 name: panel5 venous blood potassium assay def: "An analyte assay that measures the abundance of potassium in venous blood as part of a panel5 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] @@ -28294,35 +28319,41 @@ id: OBI:2100056 name: automated differential venous blood basophil count assay def: "A cytometry assay that measures the count of basophils in venous blood as part of a automated differential order" [] is_a: OBI:0003021 ! basophil assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100057 name: automated differential venous blood neutrophil count assay def: "A cytometry assay that measures the count of neutrophils in venous blood as part of a automated differential order" [] is_a: OBI:0003022 ! neutrophil assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100058 name: automated differential venous blood eosinophil count assay def: "A cytometry assay that measures the count of eosinophils in venous blood as part of a automated differential order" [] is_a: OBI:0003023 ! eosinophil assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100059 name: automated differential venous blood lymphocyte count assay def: "A cytometry assay that measures the count of lymphocytes in venous blood as part of a automated differential order" [] is_a: OBI:0003024 ! lymphocyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100060 name: automated differential venous blood monocyte count assay def: "A cytometry assay that measures the count of monocytes in venous blood as part of a automated differential order" [] is_a: OBI:0003025 ! monocyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100061 name: venous blood chloride assay def: "An analyte assay that measures the abundance of chloride in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100010 ! chloride assay [Term] @@ -28330,71 +28361,83 @@ id: OBI:2100062 name: CBC with automated differential venous blood RBC count assay def: "A cytometry assay that measures the count of RBCs in venous blood as part of a CBC with automated differential order" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100063 name: CBC with automated differential venous blood platelet count assay def: "A cytometry assay that measures the count of platelets in venous blood as part of a CBC with automated differential order" [] is_a: OBI:0003028 ! platelet assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100064 name: CBC with automated differential venous blood WBC count assay def: "A cytometry assay that measures the count of WBCs in venous blood as part of a CBC with automated differential order" [] is_a: OBI:0001977 ! cytometry assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100065 name: CBC with automated differential venous blood hematocrit assay def: "A cytometry assay that measures the proportion of red blood cells in venous blood as part of a CBC with automated differential order" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100066 name: CBC with automated differential venous blood hemoglobin assay def: "An analyte assay that measures the abundance of hemoglobin in venous blood as part of a CBC with automated differential order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100014 ! hemoglobin assay [Term] id: OBI:2100067 name: venous blood phosphate assay def: "An analyte assay that measures the abundance of phosphate in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100015 ! phosphate ion assay [Term] id: OBI:2100068 name: liver injury venous blood alanine aminotransferase assay def: "An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a liver injury order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100016 ! alanine aminotransferase assay [Term] id: OBI:2100069 name: liver injury venous blood human alkaline phosphatase assay def: "An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a liver injury order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100017 ! alkaline phosphatase (human) assay [Term] id: OBI:2100070 name: liver injury venous blood bilirubin assay def: "An analyte assay that measures the abundance of bilirubin in venous blood as part of a liver injury order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100018 ! bilirubin IXalpha assay [Term] id: OBI:2100071 name: liver injury venous blood human aspartate aminotransferase assay def: "An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a liver injury order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100019 ! aspartate aminotransferase (human) assay [Term] id: OBI:2100072 name: venous blood glucose assay def: "An analyte assay that measures the abundance of glucose in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] id: OBI:2100073 name: venous blood magnesium assay def: "An analyte assay that measures the abundance of magnesium in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100021 ! magnesium cation assay [Term] @@ -28402,29 +28445,34 @@ id: OBI:2100074 name: CBC venous blood RBC count assay def: "A cytometry assay that measures the count of RBCs in venous blood as part of a CBC order" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100075 name: CBC venous blood WBC count assay def: "A cytometry assay that measures the count of WBCs in venous blood as part of a CBC order" [] is_a: OBI:0001977 ! cytometry assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100076 name: CBC venous blood hematocrit assay def: "A cytometry assay that measures the proportion of red blood cells in venous blood as part of a CBC order" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100077 name: CBC venous blood platelet count assay def: "A cytometry assay that measures the count of platelets in venous blood as part of a CBC order" [] is_a: OBI:0003028 ! platelet assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100078 name: CBC venous blood hemoglobin assay def: "An analyte assay that measures the abundance of hemoglobin in venous blood as part of a CBC order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100014 ! hemoglobin assay [Term] @@ -28432,11 +28480,13 @@ id: OBI:2100079 name: corrected venous blood leukocyte count assay def: "A cytometry assay that measures the count of leukocytes in venous blood as part of a corrected order" [] is_a: OBI:0001977 ! cytometry assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100080 name: liver evaluation venous blood bilirubin assay def: "An analyte assay that measures the abundance of bilirubin in venous blood as part of a liver evaluation order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100018 ! bilirubin IXalpha assay [Term] @@ -28444,89 +28494,104 @@ id: OBI:2100081 name: liver evaluation venous blood globulin assay def: "An analyte assay that measures the abundance of globulin in venous blood as part of a liver evaluation order" [] is_a: OBI:0003015 ! globulin assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100082 name: liver evaluation venous blood albumin assay def: "An analyte assay that measures the abundance of albumin in venous blood as part of a liver evaluation order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100022 ! albumin assay [Term] id: OBI:2100083 name: liver evaluation venous blood human aspartate aminotransferase assay def: "An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a liver evaluation order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100019 ! aspartate aminotransferase (human) assay [Term] id: OBI:2100084 name: liver evaluation venous blood alanine aminotransferase assay def: "An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a liver evaluation order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100016 ! alanine aminotransferase assay [Term] id: OBI:2100085 name: liver evaluation venous blood human alkaline phosphatase assay def: "An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a liver evaluation order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100017 ! alkaline phosphatase (human) assay [Term] id: OBI:2100086 name: liver evaluation venous blood protein assay def: "An analyte assay that measures the abundance of protein in venous blood as part of a liver evaluation order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100087 name: basic metabolic panel venous blood chloride assay def: "An analyte assay that measures the abundance of chloride in venous blood as part of a basic metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100010 ! chloride assay [Term] id: OBI:2100088 name: basic metabolic panel venous blood potassium assay def: "An analyte assay that measures the abundance of potassium in venous blood as part of a basic metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] id: OBI:2100089 name: basic metabolic panel venous blood sodium assay def: "An analyte assay that measures the abundance of sodium in venous blood as part of a basic metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] id: OBI:2100090 name: basic metabolic panel venous blood creatinine assay def: "An analyte assay that measures the abundance of creatinine in venous blood as part of a basic metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100003 ! creatinine assay [Term] id: OBI:2100091 name: basic metabolic panel venous blood glucose assay def: "An analyte assay that measures the abundance of glucose in venous blood as part of a basic metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] id: OBI:2100092 name: basic metabolic panel venous blood calcium assay def: "An analyte assay that measures the abundance of calcium in venous blood as part of a basic metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100093 name: basic metabolic panel venous blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a basic metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] id: OBI:2100094 name: venous blood creatine kinase assay def: "An analyte assay that measures the abundance of creatine kinase in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100025 ! creatine kinase assay [Term] id: OBI:2100095 name: venous blood calcium assay def: "An analyte assay that measures the abundance of calcium in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] @@ -28534,11 +28599,13 @@ id: OBI:2100096 name: venous blood ferritin assay def: "An assay that measures ferritin in venous blood" [] is_a: OBI:0003009 ! ferritin assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100097 name: total venous blood calcium assay def: "An analyte assay that measures the abundance of calcium in venous blood as part of a total order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] @@ -28546,137 +28613,159 @@ id: OBI:2100098 name: venous blood iron assay def: "An analyte assay that measures the abundance of iron in venous blood" [] is_a: OBI:0003011 ! iron assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100099 name: CBC with manual differential venous blood band neutrophil count assay def: "A cytometry assay that measures the count of band neutrophils in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0003022 ! neutrophil assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100100 name: CBC with manual differential venous blood WBC count assay def: "A cytometry assay that measures the count of WBCs in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0001977 ! cytometry assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100101 name: CBC with manual differential venous blood eosinophil count assay def: "A cytometry assay that measures the count of eosinophils in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0003023 ! eosinophil assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100102 name: CBC with manual differential venous blood lymphocyte count assay def: "A cytometry assay that measures the count of lymphocytes in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0003024 ! lymphocyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100103 name: CBC with manual differential venous blood nucleated RBC count assay def: "A cytometry assay that measures the count of nucleated RBCs in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100104 name: CBC with manual differential venous blood monocyte count assay def: "A cytometry assay that measures the count of monocytes in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0003025 ! monocyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100105 name: CBC with manual differential venous blood segmented neutrophil count assay def: "A cytometry assay that measures the count of segmented neutrophils in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0003022 ! neutrophil assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100106 name: CBC with manual differential venous blood basophil count assay def: "A cytometry assay that measures the count of basophils in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0003021 ! basophil assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100107 name: venous blood albumin assay def: "An analyte assay that measures the abundance of albumin in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100022 ! albumin assay [Term] id: OBI:2100108 name: cardiac enzymes venous blood creatine kinase assay def: "An analyte assay that measures the abundance of creatine kinase in venous blood as part of a cardiac enzymes order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100025 ! creatine kinase assay [Term] id: OBI:2100109 name: venous blood haptoglobin assay def: "An analyte assay that measures the abundance of haptoglobin in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100110 name: venous blood lactate dehydrogenase assay def: "An assay that measures lactate dehydrogenase in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100028 ! lactate dehydrogenase complex assay [Term] id: OBI:2100111 name: venous blood prealbunin assay def: "An analyte assay that measures the abundance of prealbunin in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100112 name: lipid panel venous blood triglyceride assay def: "An analyte assay that measures the abundance of triglyceride in venous blood as part of a lipid panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100029 ! triglyceride assay [Term] id: OBI:2100113 name: lipid panel venous blood high density lipoprotein assay def: "An analyte assay that measures the abundance of high density lipoprotein in venous blood as part of a lipid panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100030 ! high-density lipoprotein cholesterol assay [Term] id: OBI:2100114 name: lipid panel venous blood cholesterol assay def: "An analyte assay that measures the abundance of cholesterol in venous blood as part of a lipid panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100031 ! cholesterol assay [Term] id: OBI:2100115 name: lipid panel venous blood low density lipoprotein assay def: "An analyte assay that measures the abundance of low density lipoprotein in venous blood as part of a lipid panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100032 ! low-density lipoprotein cholesterol assay [Term] id: OBI:2100116 name: venous blood hemoglobin A1c assay def: "An assay that measures hemoglobin A1c in venous blood" [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100117 name: venous blood uric acid assay def: "An analyte assay that measures the abundance of uric acid in venous blood" [] is_a: OBI:0003014 ! uric acid assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100118 name: total venous blood protein assay def: "An analyte assay that measures the abundance of protein in venous blood as part of a total order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100119 name: venous blood thyroid stimulating hormone assay def: "An analyte assay that measures the abundance of thyroid stimulating hormone in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100033 ! thyroid stimulating hormone assay [Term] id: OBI:2100120 name: venous blood prostate specific antigen assay def: "An analyte assay that measures the abundance of prostate specific antigen in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100034 ! prostate-specific antigen assay [Term] @@ -28689,12 +28778,14 @@ is_a: OBI:0003043 ! urine assay id: OBI:2100122 name: T4 uptake venous blood T4 assay def: "An analyte assay that measures the abundance of T4 in venous blood as part of a T4 uptake order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100035 ! thyroxine assay [Term] id: OBI:2100123 name: arterial blood glucose assay def: "An analyte assay that measures the abundance of glucose in arterial blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] @@ -28702,47 +28793,55 @@ id: OBI:2100124 name: CBC with manual differential venous blood cell count assay def: "A cytometry assay that measures the count of cells in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0001977 ! cytometry assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100125 name: hemoglobin oxygen saturation arterial blood oxygen assay def: "An analyte assay that measures the abundance of oxygen in arterial blood as part of a hemoglobin oxygen saturation order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100036 ! elemental oxygen assay [Term] id: OBI:2100126 name: hemoglobin oxygen saturation arterial blood hemoglobin assay def: "An analyte assay that measures the abundance of hemoglobin in arterial blood as part of a hemoglobin oxygen saturation order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100014 ! hemoglobin assay [Term] id: OBI:2100127 name: inpatient profile venous blood sodium assay def: "An analyte assay that measures the abundance of sodium in venous blood as part of a inpatient profile order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] id: OBI:2100128 name: inpatient profile venous blood creatinine assay def: "An analyte assay that measures the abundance of creatinine in venous blood as part of a inpatient profile order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100003 ! creatinine assay [Term] id: OBI:2100129 name: inpatient profile venous blood potassium assay def: "An analyte assay that measures the abundance of potassium in venous blood as part of a inpatient profile order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] id: OBI:2100130 name: inpatient profile venous blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a inpatient profile order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] id: OBI:2100131 name: venous blood folic acid assay def: "An analyte assay that measures the abundance of folic acid in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100037 ! folic acids assay [Term] @@ -28750,17 +28849,20 @@ id: OBI:2100132 name: count venous blood reticulocyte count assay def: "A cytometry assay that measures the count of reticulocytes in venous blood as part of a count order" [] is_a: OBI:0003026 ! reticulocyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100133 name: venous blood potassium assay def: "An analyte assay that measures the abundance of potassium in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] id: OBI:2100134 name: venous blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] @@ -28768,11 +28870,13 @@ id: OBI:2100135 name: venous blood transferrin assay def: "An analyte assay that measures the abundance of transferrin in venous blood" [] is_a: OBI:0003013 ! transferrin assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100136 name: venous blood sodium assay def: "An analyte assay that measures the abundance of sodium in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] @@ -28807,18 +28911,21 @@ is_a: OBI:2100039 ! osmolality assay id: OBI:2100141 name: cooximitery arterial blood oxygen assay def: "An analyte assay that measures the abundance of oxygen in arterial blood as part of a cooximitery order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100036 ! elemental oxygen assay [Term] id: OBI:2100142 name: cooximitery arterial blood hemoglobin assay def: "An analyte assay that measures the abundance of hemoglobin in arterial blood as part of a cooximitery order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100014 ! hemoglobin assay [Term] id: OBI:2100143 name: cooximitery arterial blood methemoglobin assay def: "An analyte assay that measures the abundance of methemoglobin in arterial blood as part of a cooximitery order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100040 ! methemoglobin assay [Term] @@ -28839,6 +28946,7 @@ is_a: OBI:2100004 ! potassium(1+) assay id: OBI:2100146 name: Biosite cardiac panel arterial blood creatine kinase MB assay def: "An assay that measures creatine kinase MB in arterial blood as part of a Biosite cardiac panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100041 ! cytosolic creatine kinase complex, MB-type assay [Term] @@ -28846,101 +28954,118 @@ id: OBI:2100147 name: venous blood fibrinogen assay def: "An assay that measures fibrinogen in venous blood" [] is_a: OBI:0003010 ! fibrinogen assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100148 name: comprehensive metabolic panel venous blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a comprehensive metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] id: OBI:2100149 name: comprehensive metabolic panel venous blood calcium assay def: "An analyte assay that measures the abundance of calcium in venous blood as part of a comprehensive metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100150 name: comprehensive metabolic panel venous blood potassium assay def: "An analyte assay that measures the abundance of potassium in venous blood as part of a comprehensive metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] id: OBI:2100151 name: comprehensive metabolic panel venous blood sodium assay def: "An analyte assay that measures the abundance of sodium in venous blood as part of a comprehensive metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] id: OBI:2100152 name: comprehensive metabolic panel venous blood glucose assay def: "An analyte assay that measures the abundance of glucose in venous blood as part of a comprehensive metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] id: OBI:2100153 name: comprehensive metabolic panel venous blood albumin assay def: "An analyte assay that measures the abundance of albumin in venous blood as part of a comprehensive metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100022 ! albumin assay [Term] id: OBI:2100154 name: comprehensive metabolic panel venous blood human alkaline phosphatase assay def: "An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a comprehensive metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100017 ! alkaline phosphatase (human) assay [Term] id: OBI:2100155 name: comprehensive metabolic panel venous blood bilirubin assay def: "An analyte assay that measures the abundance of bilirubin in venous blood as part of a comprehensive metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100018 ! bilirubin IXalpha assay [Term] id: OBI:2100156 name: comprehensive metabolic panel venous blood chloride assay def: "An analyte assay that measures the abundance of chloride in venous blood as part of a comprehensive metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100010 ! chloride assay [Term] id: OBI:2100157 name: comprehensive metabolic panel venous blood human aspartate aminotransferase assay def: "An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a comprehensive metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100019 ! aspartate aminotransferase (human) assay [Term] id: OBI:2100158 name: comprehensive metabolic panel venous blood protein assay def: "An analyte assay that measures the abundance of protein in venous blood as part of a comprehensive metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100159 name: comprehensive metabolic panel venous blood creatinine assay def: "An analyte assay that measures the abundance of creatinine in venous blood as part of a comprehensive metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100003 ! creatinine assay [Term] id: OBI:2100160 name: comprehensive metabolic panel venous blood alanine aminotransferase assay def: "An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a comprehensive metabolic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100016 ! alanine aminotransferase assay [Term] id: OBI:2100161 name: venous blood LDH assay def: "An assay that measures LDH in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100028 ! lactate dehydrogenase complex assay [Term] id: OBI:2100162 name: venous blood creatine kinase MB assay def: "An assay that measures creatine kinase MB in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100041 ! cytosolic creatine kinase complex, MB-type assay [Term] id: OBI:2100163 name: venous blood lactic acid assay def: "An assay that measures lactic acid in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100042 ! rac-lactic acid assay [Term] @@ -28948,41 +29073,48 @@ id: OBI:2100164 name: venous blood hematocrit assay def: "A cytometry assay that measures the proportion of red blood cells in venous blood" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100165 name: venous blood creatinine assay def: "An analyte assay that measures the abundance of creatinine in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100003 ! creatinine assay [Term] id: OBI:2100166 name: blood gas venous blood oxygen assay def: "An analyte assay that measures the abundance of oxygen in venous blood as part of a blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100036 ! elemental oxygen assay [Term] id: OBI:2100167 name: ionized venous blood ionized calcium assay def: "An analyte assay that measures the abundance of ionized calcium in venous blood as part of a ionized order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100168 name: blood gas venous blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] id: OBI:2100169 name: blood gas venous blood bicarbonate assay def: "An analyte assay that measures the abundance of bicarbonate in venous blood as part of a blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100043 ! hydrogencarbonate assay [Term] id: OBI:2100170 name: arterial blood creatinine assay def: "An analyte assay that measures the abundance of creatinine in arterial blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100003 ! creatinine assay [Term] @@ -28990,11 +29122,13 @@ id: OBI:2100171 name: venous blood tacrolimus assay def: "An analyte assay that measures the abundance of tacrolimus in venous blood" [] is_a: OBI:0000443 ! analyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100172 name: random venous blood vancomycin assay def: "An analyte assay that measures the abundance of vancomycin in venous blood as part of a random order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100044 ! vancomycin assay [Term] @@ -29002,77 +29136,87 @@ id: OBI:2100173 name: venous blood mycophenolic acid assay def: "An analyte assay that measures the abundance of mycophenolic acid in venous blood" [] is_a: OBI:0000443 ! analyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100174 name: non-vented blood gas arterial blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a non-vented blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] id: OBI:2100175 name: non-vented blood gas arterial blood oxygen assay def: "An analyte assay that measures the abundance of oxygen in arterial blood as part of a non-vented blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100036 ! elemental oxygen assay [Term] id: OBI:2100176 name: non-vented blood gas arterial blood bicarbonate assay def: "An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a non-vented blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100043 ! hydrogencarbonate assay [Term] id: OBI:2100177 name: quantitative venous blood IgG assay def: "An assay that measures IgG in venous blood as part of a quantitative order" [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100178 name: quantitative venous blood IgM assay def: "An assay that measures IgM in venous blood as part of a quantitative order" [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100179 name: quantitative venous blood IgA assay def: "An assay that measures IgA in venous blood as part of a quantitative order" [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100180 name: arterial blood sodium assay def: "An analyte assay that measures the abundance of sodium in arterial blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] id: OBI:2100181 name: arterial blood potassium assay def: "An analyte assay that measures the abundance of potassium in arterial blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] id: OBI:2100182 name: ionized arterial blood calcium assay def: "An analyte assay that measures the abundance of calcium in arterial blood as part of a ionized order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100183 name: vented blood gas arterial blood bicarbonate assay def: "An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a vented blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100043 ! hydrogencarbonate assay [Term] id: OBI:2100184 name: vented blood gas arterial blood oxygen assay def: "An analyte assay that measures the abundance of oxygen in arterial blood as part of a vented blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100036 ! elemental oxygen assay [Term] id: OBI:2100185 name: vented blood gas arterial blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a vented blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] @@ -29080,17 +29224,20 @@ id: OBI:2100186 name: arterial blood hematocrit assay def: "A cytometry assay that measures the proportion of red blood cells in arterial blood" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100187 name: arterial blood chloride assay def: "An analyte assay that measures the abundance of chloride in arterial blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100010 ! chloride assay [Term] id: OBI:2100188 name: arterial blood hemoglobin assay def: "An analyte assay that measures the abundance of hemoglobin in arterial blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100014 ! hemoglobin assay [Term] @@ -29098,71 +29245,83 @@ id: OBI:2100189 name: GEM premier blood gas venous blood hematocrit assay def: "A cytometry assay that measures the proportion of red blood cells in venous blood as part of a GEM premier blood gas order" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100190 name: GEM premier blood gas venous blood ionized calcium assay def: "An analyte assay that measures the abundance of ionized calcium in venous blood as part of a GEM premier blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100191 name: GEM premier blood gas venous blood potassium assay def: "An analyte assay that measures the abundance of potassium in venous blood as part of a GEM premier blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] id: OBI:2100192 name: GEM premier blood gas venous blood oxygen assay def: "An analyte assay that measures the abundance of oxygen in venous blood as part of a GEM premier blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100036 ! elemental oxygen assay [Term] id: OBI:2100193 name: GEM premier blood gas venous blood hemoglobin assay def: "An analyte assay that measures the abundance of hemoglobin in venous blood as part of a GEM premier blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100014 ! hemoglobin assay [Term] id: OBI:2100194 name: GEM premier blood gas venous blood bicarbonate assay def: "An analyte assay that measures the abundance of bicarbonate in venous blood as part of a GEM premier blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100043 ! hydrogencarbonate assay [Term] id: OBI:2100195 name: GEM premier blood gas venous blood glucose assay def: "An analyte assay that measures the abundance of glucose in venous blood as part of a GEM premier blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] id: OBI:2100196 name: GEM premier blood gas venous blood sodium assay def: "An analyte assay that measures the abundance of sodium in venous blood as part of a GEM premier blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] id: OBI:2100197 name: GEM premier blood gas venous blood lactic acid assay def: "An assay that measures lactic acid in venous blood as part of a GEM premier blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100042 ! rac-lactic acid assay [Term] id: OBI:2100198 name: GEM premier blood gas venous blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a GEM premier blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] id: OBI:2100199 name: trough venous blood tobramycin assay def: "An analyte assay that measures the abundance of tobramycin in venous blood as part of a trough order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100045 ! tobramycin assay [Term] id: OBI:2100200 name: random venous blood tobramycin assay def: "An analyte assay that measures the abundance of tobramycin in venous blood as part of a random order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100045 ! tobramycin assay [Term] @@ -29170,11 +29329,13 @@ id: OBI:2100201 name: CBC with manual differential venous blood metamyelocyte count assay def: "A cytometry assay that measures the count of metamyelocytes in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0003017 ! metamyelocyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100202 name: arterial blood lactic acid assay def: "An assay that measures lactic acid in arterial blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100042 ! rac-lactic acid assay [Term] @@ -29182,12 +29343,14 @@ id: OBI:2100203 name: venous blood 25-hydroxyvitamin D2 assay def: "An analyte assay that measures the abundance of 25-hydroxyvitamin D2 in venous blood" [] is_a: OBI:0000443 ! analyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100204 name: venous blood digoxin assay def: "An analyte assay that measures the abundance of digoxin in venous blood" [] is_a: OBI:0000443 ! analyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100205 @@ -29200,90 +29363,104 @@ is_a: OBI:2100023 ! protein assay id: OBI:2100206 name: venous blood tobramycin assay def: "An analyte assay that measures the abundance of tobramycin in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100045 ! tobramycin assay [Term] id: OBI:2100207 name: CBC with manual differential venous blood myelocyte count assay def: "A cytometry assay that measures the count of myelocytes in venous blood as part of a CBC with manual differential order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:0003165 ! myelocyte count assay [Term] id: OBI:2100208 name: SPEP protein electrophoresis venous blood beta-globin assay def: "An analyte assay that measures the abundance of beta-globin in venous blood as part of a SPEP protein electrophoresis order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100209 name: SPEP protein electrophoresis venous blood albumin assay def: "An analyte assay that measures the abundance of albumin in venous blood as part of a SPEP protein electrophoresis order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100022 ! albumin assay [Term] id: OBI:2100210 name: SPEP protein electrophoresis venous blood protein assay def: "An analyte assay that measures the abundance of protein in venous blood as part of a SPEP protein electrophoresis order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100211 name: trough venous blood vancomycin assay def: "An analyte assay that measures the abundance of vancomycin in venous blood as part of a trough order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100044 ! vancomycin assay [Term] id: OBI:2100212 name: hepatic panel venous blood protein assay def: "An analyte assay that measures the abundance of protein in venous blood as part of a hepatic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100213 name: hepatic panel venous blood bilirubin assay def: "An analyte assay that measures the abundance of bilirubin in venous blood as part of a hepatic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100018 ! bilirubin IXalpha assay [Term] id: OBI:2100214 name: hepatic panel venous blood alanine aminotransferase assay def: "An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a hepatic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100016 ! alanine aminotransferase assay [Term] id: OBI:2100215 name: hepatic panel venous blood human aspartate aminotransferase assay def: "An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a hepatic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100019 ! aspartate aminotransferase (human) assay [Term] id: OBI:2100216 name: hepatic panel venous blood albumin assay def: "An analyte assay that measures the abundance of albumin in venous blood as part of a hepatic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100022 ! albumin assay [Term] id: OBI:2100217 name: hepatic panel venous blood human alkaline phosphatase assay def: "An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a hepatic panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100017 ! alkaline phosphatase (human) assay [Term] id: OBI:2100218 name: estimated venous blood glomerular filtration assay def: "An assay that measures glomerular filtration in venous blood as part of a estimated order" [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100219 name: DT60 venous blood creatinine assay def: "An analyte assay that measures the abundance of creatinine in venous blood as part of a DT60 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100003 ! creatinine assay [Term] id: OBI:2100220 name: fasting venous blood glucose assay def: "An analyte assay that measures the abundance of glucose in venous blood as part of a fasting order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] @@ -29291,203 +29468,236 @@ id: OBI:2100221 name: random venous blood amikacin assay def: "An analyte assay that measures the abundance of amikacin in venous blood as part of a random order" [] is_a: OBI:0000443 ! analyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100222 name: venous blood ammonia assay def: "An analyte assay that measures the abundance of ammonia in venous blood" [] is_a: OBI:0000443 ! analyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100223 name: venous blood GGT assay def: "An analyte assay that measures the abundance of GGT in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100224 name: chem11 venous blood phosphate assay def: "An analyte assay that measures the abundance of phosphate in venous blood as part of a chem11 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100015 ! phosphate ion assay [Term] id: OBI:2100225 name: chem11 venous blood potassium assay def: "An analyte assay that measures the abundance of potassium in venous blood as part of a chem11 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] id: OBI:2100226 name: chem11 venous blood calcium assay def: "An analyte assay that measures the abundance of calcium in venous blood as part of a chem11 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100227 name: chem11 venous blood glucose assay def: "An analyte assay that measures the abundance of glucose in venous blood as part of a chem11 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] id: OBI:2100228 name: chem11 venous blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a chem11 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] id: OBI:2100229 name: chem11 venous blood albumin assay def: "An analyte assay that measures the abundance of albumin in venous blood as part of a chem11 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100022 ! albumin assay [Term] id: OBI:2100230 name: chem11 venous blood sodium assay def: "An analyte assay that measures the abundance of sodium in venous blood as part of a chem11 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] id: OBI:2100231 name: chem11 venous blood magnesium assay def: "An analyte assay that measures the abundance of magnesium in venous blood as part of a chem11 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100021 ! magnesium cation assay [Term] id: OBI:2100232 name: chem11 venous blood creatinine assay def: "An analyte assay that measures the abundance of creatinine in venous blood as part of a chem11 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100003 ! creatinine assay [Term] id: OBI:2100233 name: chem11 venous blood chloride assay def: "An analyte assay that measures the abundance of chloride in venous blood as part of a chem11 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100010 ! chloride assay [Term] id: OBI:2100234 name: total venous blood IgE assay def: "An assay that measures IgE in venous blood as part of a total order" [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100235 name: chem16 venous blood human aspartate aminotransferase assay def: "An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100019 ! aspartate aminotransferase (human) assay [Term] id: OBI:2100236 name: chem16 venous blood creatinine assay def: "An analyte assay that measures the abundance of creatinine in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100003 ! creatinine assay [Term] id: OBI:2100237 name: chem16 venous blood magnesium assay def: "An analyte assay that measures the abundance of magnesium in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100021 ! magnesium cation assay [Term] id: OBI:2100238 name: chem16 venous blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] id: OBI:2100239 name: chem16 venous blood glucose assay def: "An analyte assay that measures the abundance of glucose in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] id: OBI:2100240 name: chem16 venous blood calcium assay def: "An analyte assay that measures the abundance of calcium in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100241 name: chem16 venous blood triglyceride assay def: "An analyte assay that measures the abundance of triglyceride in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100029 ! triglyceride assay [Term] id: OBI:2100242 name: chem16 venous blood sodium assay def: "An analyte assay that measures the abundance of sodium in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] id: OBI:2100243 name: chem16 venous blood phosphate assay def: "An analyte assay that measures the abundance of phosphate in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100015 ! phosphate ion assay [Term] id: OBI:2100244 name: chem16 venous blood human alkaline phosphatase assay def: "An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100017 ! alkaline phosphatase (human) assay [Term] id: OBI:2100245 name: chem16 venous blood albumin assay def: "An analyte assay that measures the abundance of albumin in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100022 ! albumin assay [Term] id: OBI:2100246 name: chem16 venous blood bilirubin assay def: "An analyte assay that measures the abundance of bilirubin in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100018 ! bilirubin IXalpha assay [Term] id: OBI:2100247 name: chem16 venous blood chloride assay def: "An analyte assay that measures the abundance of chloride in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100010 ! chloride assay [Term] id: OBI:2100248 name: chem16 venous blood alanine aminotransferase assay def: "An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100016 ! alanine aminotransferase assay [Term] id: OBI:2100249 name: chem16 venous blood potassium assay def: "An analyte assay that measures the abundance of potassium in venous blood as part of a chem16 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] id: OBI:2100250 name: POC chem8 arterial blood glucose assay def: "An analyte assay that measures the abundance of glucose in arterial blood as part of a POC chem8 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] id: OBI:2100251 name: POC chem8 arterial blood ionized calcium assay def: "An analyte assay that measures the abundance of ionized calcium in arterial blood as part of a POC chem8 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100252 name: POC chem8 arterial blood potassium assay def: "An analyte assay that measures the abundance of potassium in arterial blood as part of a POC chem8 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] id: OBI:2100253 name: POC chem8 arterial blood sodium assay def: "An analyte assay that measures the abundance of sodium in arterial blood as part of a POC chem8 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] id: OBI:2100254 name: POC chem8 arterial blood creatinine assay def: "An analyte assay that measures the abundance of creatinine in arterial blood as part of a POC chem8 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100003 ! creatinine assay [Term] @@ -29495,17 +29705,20 @@ id: OBI:2100255 name: POC chem8 arterial blood hematocrit assay def: "A cytometry assay that measures the proportion of red blood cells in arterial blood as part of a POC chem8 order" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100256 name: POC chem8 arterial blood chloride assay def: "An analyte assay that measures the abundance of chloride in arterial blood as part of a POC chem8 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100010 ! chloride assay [Term] id: OBI:2100257 name: peak venous blood tobramycin assay def: "An analyte assay that measures the abundance of tobramycin in venous blood as part of a peak order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100045 ! tobramycin assay [Term] @@ -29519,18 +29732,21 @@ is_a: OBI:2100003 ! creatinine assay id: OBI:2100259 name: intact venous blood PTH assay def: "An analyte assay that measures the abundance of PTH in venous blood as part of a intact order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100034 ! prostate-specific antigen assay [Term] id: OBI:2100260 name: total venous blood PSA assay def: "An analyte assay that measures the abundance of PSA in venous blood as part of a total order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100034 ! prostate-specific antigen assay [Term] id: OBI:2100261 name: total venous blood T3 assay def: "An analyte assay that measures the abundance of T3 in venous blood as part of a total order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100046 ! 3,3',5'-triiodothyronine assay [Term] @@ -29544,12 +29760,14 @@ is_a: OBI:2100023 ! protein assay id: OBI:2100263 name: total venous blood cholesterol assay def: "An analyte assay that measures the abundance of cholesterol in venous blood as part of a total order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100031 ! cholesterol assay [Term] id: OBI:2100264 name: venous blood triglyceride assay def: "An analyte assay that measures the abundance of triglyceride in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100029 ! triglyceride assay [Term] @@ -29585,53 +29803,62 @@ id: OBI:2100269 name: venous blood dehydroepiandrosterone assay def: "An analyte assay that measures the abundance of dehydroepiandrosterone in venous blood" [] is_a: OBI:0000443 ! analyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100270 name: venous blood cortisol assay def: "An analyte assay that measures the abundance of cortisol in venous blood" [] is_a: OBI:0000443 ! analyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100271 name: ABL90 panel arterial blood sodium assay def: "An analyte assay that measures the abundance of sodium in arterial blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] id: OBI:2100272 name: ABL90 panel arterial blood oxygen assay def: "An analyte assay that measures the abundance of oxygen in arterial blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100036 ! elemental oxygen assay [Term] id: OBI:2100273 name: ABL90 panel arterial blood glucose assay def: "An analyte assay that measures the abundance of glucose in arterial blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] id: OBI:2100274 name: ABL90 panel arterial blood lactic acid assay def: "An assay that measures lactic acid in arterial blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100042 ! rac-lactic acid assay [Term] id: OBI:2100275 name: ABL90 panel arterial blood hemoglobin assay def: "An analyte assay that measures the abundance of hemoglobin in arterial blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100014 ! hemoglobin assay [Term] id: OBI:2100276 name: ABL90 panel arterial blood chloride assay def: "An analyte assay that measures the abundance of chloride in arterial blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100010 ! chloride assay [Term] id: OBI:2100277 name: ABL90 panel arterial blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] @@ -29639,29 +29866,33 @@ id: OBI:2100278 name: ABL90 panel arterial blood hematocrit assay def: "A cytometry assay that measures the proportion of red blood cells in arterial blood as part of a ABL90 panel order" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100279 name: ABL90 panel arterial blood calcium assay def: "An analyte assay that measures the abundance of calcium in arterial blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100280 name: ABL90 panel arterial blood temperature assay def: "An assay that measures temperature in arterial blood as part of a ABL90 panel order" [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100281 name: ABL90 panel arterial blood bicarbonate assay def: "An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100043 ! hydrogencarbonate assay [Term] id: OBI:2100282 name: ABL90 panel arterial blood potassium assay def: "An analyte assay that measures the abundance of potassium in arterial blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] @@ -29669,29 +29900,34 @@ id: OBI:2100283 name: CBC with manual differential venous blood promyelocyte count assay def: "A cytometry assay that measures the count of promyelocytes in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0003019 ! promyelocyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100284 name: ABL90 panel venous blood glucose assay def: "An analyte assay that measures the abundance of glucose in venous blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] id: OBI:2100285 name: ABL90 panel venous blood hemoglobin assay def: "An analyte assay that measures the abundance of hemoglobin in venous blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100014 ! hemoglobin assay [Term] id: OBI:2100286 name: ABL90 panel venous blood ionized calcium assay def: "An analyte assay that measures the abundance of ionized calcium in venous blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100287 name: ABL90 panel venous blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in venous blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] @@ -29699,53 +29935,62 @@ id: OBI:2100288 name: ABL90 panel venous blood hematocrit assay def: "A cytometry assay that measures the proportion of red blood cells in venous blood as part of a ABL90 panel order" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100289 name: ABL90 panel venous blood sodium assay def: "An analyte assay that measures the abundance of sodium in venous blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] id: OBI:2100290 name: ABL90 panel venous blood oxygen assay def: "An analyte assay that measures the abundance of oxygen in venous blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100036 ! elemental oxygen assay [Term] id: OBI:2100291 name: ABL90 panel venous blood bicarbonate assay def: "An analyte assay that measures the abundance of bicarbonate in venous blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100043 ! hydrogencarbonate assay [Term] id: OBI:2100292 name: ABL90 panel venous blood lactic acid assay def: "An assay that measures lactic acid in venous blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100042 ! rac-lactic acid assay [Term] id: OBI:2100293 name: ABL90 panel venous blood chloride assay def: "An analyte assay that measures the abundance of chloride in venous blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100010 ! chloride assay [Term] id: OBI:2100294 name: venous blood T4 assay def: "An analyte assay that measures the abundance of T4 in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100035 ! thyroxine assay [Term] id: OBI:2100295 name: free venous blood T4 assay def: "An analyte assay that measures the abundance of T4 in venous blood as part of a free order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100035 ! thyroxine assay [Term] id: OBI:2100296 name: ABL90 panel venous blood potassium assay def: "An analyte assay that measures the abundance of potassium in venous blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] @@ -29759,48 +30004,56 @@ is_a: OBI:2100002 ! sodium(1+) assay id: OBI:2100298 name: bone profile venous blood albumin assay def: "An analyte assay that measures the abundance of albumin in venous blood as part of a bone profile order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100022 ! albumin assay [Term] id: OBI:2100299 name: bone profile venous blood calcium assay def: "An analyte assay that measures the abundance of calcium in venous blood as part of a bone profile order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100300 name: bone profile venous blood human alkaline phosphatase assay def: "An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a bone profile order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100017 ! alkaline phosphatase (human) assay [Term] id: OBI:2100301 name: bone profile venous blood protein assay def: "An analyte assay that measures the abundance of protein in venous blood as part of a bone profile order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100302 name: bone profile venous blood phosphate assay def: "An analyte assay that measures the abundance of phosphate in venous blood as part of a bone profile order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100015 ! phosphate ion assay [Term] id: OBI:2100303 name: ABG/electrolytes arterial blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a ABG/electrolytes order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] id: OBI:2100304 name: ABG/electrolytes arterial blood oxygen assay def: "An analyte assay that measures the abundance of oxygen in arterial blood as part of a ABG/electrolytes order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100036 ! elemental oxygen assay [Term] id: OBI:2100305 name: ABG/electrolytes arterial blood ionized calcium assay def: "An analyte assay that measures the abundance of ionized calcium in arterial blood as part of a ABG/electrolytes order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] @@ -29808,17 +30061,20 @@ id: OBI:2100306 name: CBC with automated differential venous blood nucleated RBC count assay def: "A cytometry assay that measures the count of nucleated RBCs in venous blood as part of a CBC with automated differential order" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100307 name: ABL90 panel venous blood methemoglobin assay def: "An analyte assay that measures the abundance of methemoglobin in venous blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100040 ! methemoglobin assay [Term] id: OBI:2100308 name: ABL90 panel arterial blood methemoglobin assay def: "An analyte assay that measures the abundance of methemoglobin in arterial blood as part of a ABL90 panel order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100040 ! methemoglobin assay [Term] @@ -29826,29 +30082,34 @@ id: OBI:2100309 name: venous blood valproic acid assay def: "An analyte assay that measures the abundance of valproic acid in venous blood" [] is_a: OBI:0000443 ! analyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100310 name: high sensitivity cardiac/neonatal venous blood c-reactive protein assay def: "An analyte assay that measures the abundance of c-reactive protein in venous blood as part of a high sensitivity cardiac/neonatal order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100047 ! C-reactive protein assay [Term] id: OBI:2100311 name: POC arterial blood creatinine assay def: "An analyte assay that measures the abundance of creatinine in arterial blood as part of a POC order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100003 ! creatinine assay [Term] id: OBI:2100312 name: GEM4000 ANLCOOX arterial blood bicarbonate assay def: "An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a GEM4000 ANLCOOX order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100043 ! hydrogencarbonate assay [Term] id: OBI:2100313 name: GEM4000 ANLCOOX arterial blood oxygen assay def: "An analyte assay that measures the abundance of oxygen in arterial blood as part of a GEM4000 ANLCOOX order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100036 ! elemental oxygen assay [Term] @@ -29856,59 +30117,68 @@ id: OBI:2100314 name: GEM4000 ANLCOOX arterial blood hematocrit assay def: "A cytometry assay that measures the proportion of red blood cells in arterial blood as part of a GEM4000 ANLCOOX order" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100315 name: GEM4000 ANLCOOX arterial blood temperature assay def: "An assay that measures temperature in arterial blood as part of a GEM4000 ANLCOOX order" [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100316 name: GEM4000 ANLCOOX arterial blood hemoglobin assay def: "An analyte assay that measures the abundance of hemoglobin in arterial blood as part of a GEM4000 ANLCOOX order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100014 ! hemoglobin assay [Term] id: OBI:2100317 name: GEM4000 ANLCOOX arterial blood potassium assay def: "An analyte assay that measures the abundance of potassium in arterial blood as part of a GEM4000 ANLCOOX order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] id: OBI:2100318 name: GEM4000 ANLCOOX arterial blood glucose assay def: "An analyte assay that measures the abundance of glucose in arterial blood as part of a GEM4000 ANLCOOX order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] id: OBI:2100319 name: GEM4000 ANLCOOX arterial blood ionized calcium assay def: "An analyte assay that measures the abundance of ionized calcium in arterial blood as part of a GEM4000 ANLCOOX order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100320 name: GEM4000 ANLCOOX arterial blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a GEM4000 ANLCOOX order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] id: OBI:2100321 name: GEM4000 ANLCOOX arterial blood sodium assay def: "An analyte assay that measures the abundance of sodium in arterial blood as part of a GEM4000 ANLCOOX order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] id: OBI:2100322 name: ionized venous blood calcium assay def: "An analyte assay that measures the abundance of calcium in venous blood as part of a ionized order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100323 name: venous blood hemoglobin assay def: "An analyte assay that measures the abundance of hemoglobin in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100014 ! hemoglobin assay [Term] @@ -29916,23 +30186,27 @@ id: OBI:2100324 name: CBC with manual differential venous blood megakaryocyte count assay def: "A cytometry assay that measures the count of megakaryocytes in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0001977 ! cytometry assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100325 name: non-cardiac venous blood c-reactive protein assay def: "An analyte assay that measures the abundance of c-reactive protein in venous blood as part of a non-cardiac order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100047 ! C-reactive protein assay [Term] id: OBI:2100326 name: intraoperative venous blood PTH assay def: "An analyte assay that measures the abundance of PTH in venous blood as part of a intraoperative order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100034 ! prostate-specific antigen assay [Term] id: OBI:2100327 name: venous blood parathyroid hormone assay def: "An analyte assay that measures the abundance of parathyroid hormone in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] @@ -29999,42 +30273,49 @@ is_a: OBI:0003023 ! eosinophil assay id: OBI:2100338 name: liver function venous blood bilirubin assay def: "An analyte assay that measures the abundance of bilirubin in venous blood as part of a liver function order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100018 ! bilirubin IXalpha assay [Term] id: OBI:2100339 name: liver function venous blood alanine aminotransferase assay def: "An analyte assay that measures the abundance of alanine aminotransferase in venous blood as part of a liver function order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100016 ! alanine aminotransferase assay [Term] id: OBI:2100340 name: liver function venous blood human aspartate aminotransferase assay def: "An analyte assay that measures the abundance of human aspartate aminotransferase in venous blood as part of a liver function order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100019 ! aspartate aminotransferase (human) assay [Term] id: OBI:2100341 name: liver function venous blood albumin assay def: "An analyte assay that measures the abundance of albumin in venous blood as part of a liver function order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100022 ! albumin assay [Term] id: OBI:2100342 name: liver function venous blood protein assay def: "An analyte assay that measures the abundance of protein in venous blood as part of a liver function order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100343 name: liver function venous blood human alkaline phosphatase assay def: "An analyte assay that measures the abundance of human alkaline phosphatase in venous blood as part of a liver function order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100017 ! alkaline phosphatase (human) assay [Term] id: OBI:2100344 name: vitamin B12 and Folate venous blood folic acid assay def: "An analyte assay that measures the abundance of folic acid in venous blood as part of a vitamin B12 and Folate order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100037 ! folic acids assay [Term] @@ -30048,6 +30329,7 @@ id: OBI:2100346 name: venous blood reticulocyte count assay def: "A cytometry assay that measures the count of reticulocytes in venous blood" [] is_a: OBI:0003026 ! reticulocyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100347 @@ -30059,18 +30341,21 @@ is_a: OBI:2100031 ! cholesterol assay id: OBI:2100348 name: TSH reflex Free T4 venous blood thyroid stimulating hormone assay def: "An analyte assay that measures the abundance of thyroid stimulating hormone in venous blood as part of a TSH reflex Free T4 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100033 ! thyroid stimulating hormone assay [Term] id: OBI:2100349 name: direct venous blood bilirubin assay def: "An analyte assay that measures the abundance of bilirubin in venous blood as part of a direct order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100018 ! bilirubin IXalpha assay [Term] id: OBI:2100350 name: free venous blood T3 assay def: "An analyte assay that measures the abundance of T3 in venous blood as part of a free order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100046 ! 3,3',5'-triiodothyronine assay [Term] @@ -30090,41 +30375,47 @@ id: OBI:2100353 name: hemoglobin and hematocrit venous blood hematocrit assay def: "A cytometry assay that measures the proportion of red blood cells in venous blood as part of a hemoglobin and hematocrit order" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100354 name: hemoglobin and hematocrit venous blood hemoglobin assay def: "An analyte assay that measures the abundance of hemoglobin in venous blood as part of a hemoglobin and hematocrit order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100014 ! hemoglobin assay [Term] id: OBI:2100355 name: venous blood ionized calcium assay def: "An analyte assay that measures the abundance of ionized calcium in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100356 name: venous blood temperature assay def: "An assay that measures temperature in venous blood" [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100357 name: venous blood bicarbonate assay def: "An analyte assay that measures the abundance of bicarbonate in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100043 ! hydrogencarbonate assay [Term] id: OBI:2100358 name: venous blood oxygen assay def: "An analyte assay that measures the abundance of oxygen in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100036 ! elemental oxygen assay [Term] id: OBI:2100359 name: venous blood osmolality assay def: "An assay that measures osmolality in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100039 ! osmolality assay [Term] @@ -30132,11 +30423,13 @@ id: OBI:2100360 name: liver fibrosis (chronic viral hepatitis) venous blood platelet count assay def: "A cytometry assay that measures the count of platelets in venous blood as part of a liver fibrosis (chronic viral hepatitis) order" [] is_a: OBI:0003028 ! platelet assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100361 name: venous blood T3 assay def: "An analyte assay that measures the abundance of T3 in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100046 ! 3,3',5'-triiodothyronine assay [Term] @@ -30144,6 +30437,7 @@ id: OBI:2100362 name: CBC with manual differential venous blood neutrophil count assay def: "A cytometry assay that measures the count of neutrophils in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0003022 ! neutrophil assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100363 @@ -30156,6 +30450,7 @@ is_a: OBI:2100003 ! creatinine assay id: OBI:2100364 name: venous blood beta hydroxybutryic acid assay def: "An analyte assay that measures the abundance of beta hydroxybutryic acid in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100051 ! 3-hydroxybutyric acid assay [Term] @@ -30163,83 +30458,96 @@ id: OBI:2100365 name: venous blood megakaryocyte count assay def: "A cytometry assay that measures the count of megakaryocytes in venous blood" [] is_a: OBI:0001977 ! cytometry assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100366 name: venous blood nucleated RBC count assay def: "A cytometry assay that measures the count of nucleated RBCs in venous blood" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100367 name: venous blood WBC count assay def: "A cytometry assay that measures the count of WBCs in venous blood" [] is_a: OBI:0001977 ! cytometry assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100368 name: automated count venous blood reticulocyte count assay def: "A cytometry assay that measures the count of reticulocytes in venous blood as part of a automated count order" [] is_a: OBI:0003026 ! reticulocyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100369 name: total venous blood homocysteine assay def: "An analyte assay that measures the abundance of homocysteine in venous blood as part of a total order" [] is_a: OBI:0000443 ! analyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100370 name: venous blood Ceruloplasmin assay def: "An analyte assay that measures the abundance of Ceruloplasmin in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100371 name: GEM4 arterial blood bicarbonate assay def: "An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a GEM4 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100043 ! hydrogencarbonate assay [Term] id: OBI:2100372 name: GEM4 arterial blood lactic acid assay def: "An assay that measures lactic acid in arterial blood as part of a GEM4 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100042 ! rac-lactic acid assay [Term] id: OBI:2100373 name: GEM4 arterial blood hemoglobin assay def: "An analyte assay that measures the abundance of hemoglobin in arterial blood as part of a GEM4 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100014 ! hemoglobin assay [Term] id: OBI:2100374 name: GEM4 arterial blood sodium assay def: "An analyte assay that measures the abundance of sodium in arterial blood as part of a GEM4 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100002 ! sodium(1+) assay [Term] id: OBI:2100375 name: GEM4 arterial blood potassium assay def: "An analyte assay that measures the abundance of potassium in arterial blood as part of a GEM4 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100004 ! potassium(1+) assay [Term] id: OBI:2100376 name: GEM4 arterial blood temperature assay def: "An assay that measures temperature in arterial blood as part of a GEM4 order" [] -is_a: OBI:0000070 ! assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100377 name: GEM4 arterial blood glucose assay def: "An analyte assay that measures the abundance of glucose in arterial blood as part of a GEM4 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100020 ! glucose assay [Term] id: OBI:2100378 name: GEM4 arterial blood oxygen assay def: "An analyte assay that measures the abundance of oxygen in arterial blood as part of a GEM4 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100036 ! elemental oxygen assay [Term] @@ -30247,17 +30555,20 @@ id: OBI:2100379 name: GEM4 arterial blood hematocrit assay def: "A cytometry assay that measures the proportion of red blood cells in arterial blood as part of a GEM4 order" [] is_a: OBI:0003018 ! hematocrit assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100380 name: GEM4 arterial blood ionized calcium assay def: "An analyte assay that measures the abundance of ionized calcium in arterial blood as part of a GEM4 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100024 ! calcium cation assay [Term] id: OBI:2100381 name: GEM4 arterial blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a GEM4 order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] @@ -30265,11 +30576,13 @@ id: OBI:2100382 name: liver fibrosis (NAFLD) venous blood platelet count assay def: "A cytometry assay that measures the count of platelets in venous blood as part of a liver fibrosis (NAFLD) order" [] is_a: OBI:0003028 ! platelet assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100383 name: venous blood beta hydroxybutric acid assay def: "An analyte assay that measures the abundance of beta hydroxybutric acid in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100051 ! 3-hydroxybutyric acid assay [Term] @@ -30277,35 +30590,41 @@ id: OBI:2100384 name: CBC with manual differential venous blood plasma cell count assay def: "A cytometry assay that measures the count of plasma cells in venous blood as part of a CBC with manual differential order" [] is_a: OBI:0003024 ! lymphocyte assay +is_a: OBI:0003040 ! blood assay [Term] id: OBI:2100385 name: venous blood erythropoietin assay def: "An analyte assay that measures the abundance of erythropoietin in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100386 name: blood gas arterial blood oxygen assay def: "An analyte assay that measures the abundance of oxygen in arterial blood as part of a blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100036 ! elemental oxygen assay [Term] id: OBI:2100387 name: blood gas arterial blood bicarbonate assay def: "An analyte assay that measures the abundance of bicarbonate in arterial blood as part of a blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100043 ! hydrogencarbonate assay [Term] id: OBI:2100388 name: blood gas arterial blood carbon dioxide assay def: "An analyte assay that measures the abundance of carbon dioxide in arterial blood as part of a blood gas order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100001 ! carbon dioxide assay [Term] id: OBI:2100389 name: free/total venous blood PSA assay def: "An analyte assay that measures the abundance of PSA in venous blood as part of a free/total order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100034 ! prostate-specific antigen assay [Term] @@ -30361,30 +30680,35 @@ is_a: OBI:0003232 ! cerebrospinal fluid assay id: OBI:2100397 name: venous blood beta-2-microglobulin assay def: "An analyte assay that measures the abundance of beta-2-microglobulin in venous blood" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100023 ! protein assay [Term] id: OBI:2100398 name: lipid panel reflex direct venous blood low density lipoprotein assay def: "An analyte assay that measures the abundance of low density lipoprotein in venous blood as part of a Lipid panel reflex direct order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100032 ! low-density lipoprotein cholesterol assay [Term] id: OBI:2100399 name: lipid panel reflex direct venous blood triglyceride assay def: "An analyte assay that measures the abundance of triglyceride in venous blood as part of a Lipid panel reflex direct order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100029 ! triglyceride assay [Term] id: OBI:2100400 name: lipid panel reflex direct venous blood cholesterol assay def: "An analyte assay that measures the abundance of cholesterol in venous blood as part of a Lipid panel reflex direct order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100031 ! cholesterol assay [Term] id: OBI:2100401 name: lipid panel reflex direct venous blood high density lipoprotein assay def: "An analyte assay that measures the abundance of high density lipoprotein in venous blood as part of a Lipid panel reflex direct order" [] +is_a: OBI:0003040 ! blood assay is_a: OBI:2100030 ! high-density lipoprotein cholesterol assay [Term] @@ -31300,6 +31624,12 @@ name: life cycle stage def: "A spatiotemporal region encompassing some part of the life cycle of an organism." [] is_a: GO:0008150 ! biological_process +[Term] +id: UBERON:0000162 +name: cloaca +def: "Common chamber into which the intestines and excretory system opens. Arises during development in all vertebrates, but in many it becomes subdivided, lost or incorporated into other structures." [] +is_a: UBERON:0000465 ! material anatomical entity + [Term] id: UBERON:0000165 name: mouth diff --git a/views/obi_core.owl b/views/obi_core.owl index 03bd7c4e..a2b387e6 100644 --- a/views/obi_core.owl +++ b/views/obi_core.owl @@ -11,7 +11,7 @@ xmlns:terms="http://purl.org/dc/terms/" xmlns:protege="http://protege.stanford.edu/plugins/owl/protege#"> - + en Ontology for Biomedical Investigations Advisors for this project come from the IFOMIS group, Saarbruecken and from the Co-ODE group in Manchester @@ -78,7 +78,7 @@ http://creativecommons.org/licenses/by/4.0/ Ontology for Biomedical Investigations Please cite the OBI consortium http://purl.obolibrary.org/obo/obi where traditional citation is called for. However it is adequate that individual terms be attributed simply by use of the identifying PURL for the term, in projects that refer to them. - 2024-10-25 + 2024-12-05 @@ -2658,7 +2658,7 @@ editor = PRS specimen role liver section; a portion of a culture of cells; a nemotode or other animal once no longer a subject (generally killed); portion of blood from a patient. - a role borne by a material entity that is gained during a specimen collection process and that can be realized by use of the specimen in an investigation + A role borne by a material entity that is obtained during a specimen collection process and that can be realized by performing measurements or observations on the specimen. 22Jun09. The definition includes whole organisms, and can include a human. The link between specimen role and study subject role has been removed. A specimen taken as part of a case study is not considered to be a population representative, while a specimen taken as representing a population, e.g. person taken from a cohort, blood specimen taken from an animal) would be considered a population representative and would also bear material sample role. Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation. blood taken from animal: animal continues in study, whereas blood has role specimen. @@ -3046,9 +3046,10 @@ for now. specimen collection process - drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation + drawing blood from a patient for analysis, collecting a piece of a plant for depositing in a herbarium, buying meat from a butcher in order to measure its protein content in an investigation, collecting a stone from a site - A planned process with the objective of collecting a specimen. + A planned process with the objective to obtain a material entity for potential use as an input upon which measurements or observations are performed. + Definition updated following discussion on 2024-10-07 OBI dev call. Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation. Philly2013: A specimen collection can have as part a material entity acquisition, such as ordering from a bank. The distinction is that specimen collection necessarily involves the creation of a specimen role. However ordering cell lines cells from ATCC for use in an investigation is NOT a specimen collection, because the cell lines already have a specimen role. Philly2013: The specimen_role for the specimen is created during the specimen collection process. @@ -3070,7 +3071,8 @@ http://sourceforge.net/p/obi/obi-terms/716/ specimen collection objective The objective to collect bits of excrement in the rainforest. The objective to obtain a blood sample from a patient. - A objective specification to obtain a material entity for potential use as an input during an investigation. + A objective specification that is fulfilled by obtaining a material entity for potential use as an input upon which measurements or observations are performed. + OBI recommends against subclassing this term in order to avoid further parallel hierarchies between this term and specimen collection process. Bjoern Peters Bjoern Peters specimen collection objective @@ -3226,21 +3228,24 @@ http://sourceforge.net/p/obi/obi-terms/716/ - + + + + + + processed specimen - A tissue sample that has been sliced and stained for a histology study. -A blood specimen that has been centrifuged to obtain the white blood cells. A specimen that has been intentionally physically modified. + A tissue sample that has been sliced and stained for a histology study. Bjoern Peters Bjoern Peters - A tissue sample that has been sliced and stained for a histology study. processed specimen @@ -3297,6 +3302,76 @@ In the examples above, a reagent is an operational component of a device, but th + + + + + + + + + + + + + + + + cell specimen + + A specimen primarily composed of a cell or cells collected from a multicellular organism or a cell culture. + Discussed on obi call Jan 23, 2017. To improve cell specimen that include single cell specimen. Details see tracker: https://sourceforge.net/p/obi/obi-terms/828 + PERSON: Chris Stoeckert, Jie Zheng, Alexander Diehl + MO_612 cell + cell specimen + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + specimen from organism + + A specimen that derives from an anatomical part or substance arising from an organism. Examples of tissue specimen include tissue, organ, physiological system, blood, or body location (arm). + PERSON: Chris Stoeckert, Jie Zheng + tissue specimen + MO_954 organism_part + specimen from organism + + + + @@ -3605,10 +3680,9 @@ This issue is outside the scope of OBI. specimen - Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen. + Biobanking of blood taken and stored in a freezer for potential future investigations stores specimen; collecting a stone from a site. - A material entity that has the specimen role. - Note: definition is in specimen creation objective which is defined as an objective to obtain and store a material entity for potential use as an input during an investigation. + A material entity that is collected for potential use as an input upon which measurements or observations are performed. PERSON: James Malone PERSON: Philippe Rocca-Serra GROUP: OBI Biomaterial Branch @@ -3938,6 +4012,30 @@ realizes some 'host of immune response role' + + + + + material anatomical entity + Anatomical entity that has mass. + + material anatomical entity + + + + + + + + + anatomical cluster + Anatomical group whose component anatomical structures lie in close proximity to each other. + + anatomical cluster + + + + - - - - entity - - entity - - - - - - - - - continuant - An entity that exists in full at any time in which it exists at all, persists through time while maintaining its identity and has no temporal parts. - - continuant - - - - - - - - - quality - - quality - - - - - - - - - specifically dependent continuant - b is a specifically dependent continuant = Def. b is a continuant & there is some independent continuant c which is not a spatial region and which is such that b s-depends_on c at every time t during the course of b’s existence. (axiom label in BFO2 Reference: [050-003]) - - specifically dependent continuant - - - - @@ -300,18 +254,6 @@ - - - - - action specification - A directive information entity that describes an action the bearer will take. - - action specification - - - - @@ -337,18 +279,6 @@ interpreted by or directly executed by a processing unit. - - - - - information carrier - A quality of an information bearer that imparts the information content - - information carrier - - - - @@ -424,7 +354,7 @@ interpreted by or directly executed by a processing unit. - + graph A diagram that presents one or more tuples of information by mapping those tuples in to a two dimensional space in a non arbitrary way. @@ -460,7 +390,7 @@ interpreted by or directly executed by a processing unit. - + curation status specification The curation status of the term. The allowed values come from an enumerated list of predefined terms. See the specification of these instances for more detailed definitions of each enumerated value. @@ -530,18 +460,6 @@ Example: The ISO document specifying what encompasses an XML document; The instr - - - - - data about an ontology part - Data about an ontology part is a data item about a part of an ontology, for example a term - - data about an ontology part - - - - @@ -679,18 +597,6 @@ clustering algorithm. - - - - - diagram - A figure that expresses one or more propositions - - diagram - - - - @@ -727,22 +633,10 @@ clustering algorithm. - - - - - cartesian spatial coordinate datum - A cartesian spatial coordinate datum is a representation of a point in a spatial region, in which equal changes in the magnitude of a coordinate value denote length qualities with the same magnitude - - cartesian spatial coordinate datum - - - - - + one dimensional cartesian spatial coordinate datum A cartesion spatial coordinate datum that uses one value to specify a position along a one dimensional spatial region @@ -862,7 +756,7 @@ points together with a line. - + centrally registered identifier registry A code set of CRID records, each consisting of a CRID symbol and additional information which was recorded in the code set through an assigning a centrally registered identifier process. @@ -883,18 +777,6 @@ points together with a line. - - - - - code set - An information content entity that is a collection of other information content entities that has been created to identify or annotate things in a specified domain, and where the intention of its creators is that the collection has a one-to-one correspondence with those things. - - code set - - - - From c83ff101837b86b5926c6f126e3ecfa7c89917f8 Mon Sep 17 00:00:00 2001 From: Sebastian Duesing <66700705+sebastianduesing@users.noreply.github.com> Date: Thu, 19 Dec 2024 13:27:28 -0600 Subject: [PATCH 07/12] Remove references to BFO_0000001 --- src/ontology/modules/data-sets.owl | 12 ------- src/ontology/obi-edit.owl | 50 ++++++++-------------------- src/ontology/templates/data-sets.tsv | 2 +- 3 files changed, 14 insertions(+), 50 deletions(-) diff --git a/src/ontology/modules/data-sets.owl b/src/ontology/modules/data-sets.owl index cab821ed..b97be9d9 100644 --- a/src/ontology/modules/data-sets.owl +++ b/src/ontology/modules/data-sets.owl @@ -92,12 +92,6 @@ - - - - - - @@ -114,12 +108,6 @@ - - - - - - The output produced by a digital imaging technique, such as microscopy, MRI, or CT. A data set that is comprised of multidimensional structured measurements and metadata required for a morphological representation of an entity. An image data set can be the source from which an image (such as a 2D image using pixels or a 3D image using voxels) is produced. https://orcid.org/0000-0001-9625-1899 "William D. Duncan" diff --git a/src/ontology/obi-edit.owl b/src/ontology/obi-edit.owl index a9a30569..a88f008a 100644 --- a/src/ontology/obi-edit.owl +++ b/src/ontology/obi-edit.owl @@ -14,7 +14,6 @@ xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"> - @@ -59,6 +58,7 @@ + en Ontology for Biomedical Investigations @@ -1530,14 +1530,6 @@ https://sourceforge.net/tracker/index.php?func=detail&aid=3512902&group_ - - - - - - - - @@ -16638,34 +16630,18 @@ Pubmed: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867615/ - - - - - - - - - - - - - - - - - - - - - - - - - - - - + + + + + + + + + + + + diff --git a/src/ontology/templates/data-sets.tsv b/src/ontology/templates/data-sets.tsv index 749d1489..73adafd5 100644 --- a/src/ontology/templates/data-sets.tsv +++ b/src/ontology/templates/data-sets.tsv @@ -1,6 +1,6 @@ ontology ID label has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class is about is specified output of has member ID A rdfs:label AI has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=, A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE CI C 'is about' some % C 'is specified output of' some % C 'has member' some % -OBI:0003327 image data set A data set that is comprised of multidimensional structured measurements and metadata required for a morphological representation of an entity. An image data set can be the source from which an image (such as a 2D image using pixels or a 3D image using voxels) is produced. The output produced by a digital imaging technique, such as microscopy, MRI, or CT. https://orcid.org/0000-0001-9625-1899 ""William D. Duncan"",https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie"",https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik"",https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl"",https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra"",https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"" https://github.com/obi-ontology/obi/issues/1481 subclass data set entity +OBI:0003327 image data set A data set that is comprised of multidimensional structured measurements and metadata required for a morphological representation of an entity. An image data set can be the source from which an image (such as a 2D image using pixels or a 3D image using voxels) is produced. The output produced by a digital imaging technique, such as microscopy, MRI, or CT. https://orcid.org/0000-0001-9625-1899 ""William D. Duncan"",https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie"",https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik"",https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl"",https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra"",https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"" https://github.com/obi-ontology/obi/issues/1481 subclass data set OBI:0003328 magnetic resonance image data set An image data set whose information content originates from some MR imaging assay and is about some MRI participant. MRI at a Glance, ISBN 10: 1119053552 The DICOM file produced by an MRI machine when a multiple sclerosis patient undergoes a brain scan. https://orcid.org/0000-0001-9625-1899 ""William D. Duncan"",https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie"",https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik"",https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl"",https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra"",https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"" https://github.com/obi-ontology/obi/issues/1481 equivalent image data set magnetic resonance imaging participant OBI:0003331 raw image data set An image data set that encodes measurement values produced by some instrument before undergoing a data transformation. The untransformed (""k-space"") data produced by an MRI machine, prior to mathematical transformation into a form that corresponds to the anatomical structure of the brain. https://orcid.org/0000-0001-9625-1899 ""William D. Duncan"",https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie"",https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik"",https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl"",https://orcid.org/0000-0002-2104-0568 ""Lucas M. Serra"",https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"",https://orcid.org/0000-0002-1604-3078 ""Alan Ruttenberg"" https://github.com/obi-ontology/obi/issues/1481 subclass image data set OBI:0003333 computed image data set An image data set that is the output of an image data set analysis. The production of JPEG file by a digital camera. https://orcid.org/0000-0001-9625-1899 ""William D. Duncan"",https://orcid.org/0000-0001-9676-7377 ""Alexander D. Bartnik"",https://orcid.org/0000-0001-9990-8331 ""Alexander D. Diehl"",https://orcid.org/0000-0002-1604-3078 ""Alan Ruttenberg"",https://orcid.org/0000-0002-7245-3450 ""Lauren M. Wishnie"",https://orcid.org/0000-0002-9821-4132 ""Mackenzie T. Smith"" https://github.com/obi-ontology/obi/issues/1481 equivalent image data set image data set analysis From dec6bf87e44c212d85178222f671ae48c198fee7 Mon Sep 17 00:00:00 2001 From: Sebastian Duesing <66700705+sebastianduesing@users.noreply.github.com> Date: Thu, 19 Dec 2024 13:33:23 -0600 Subject: [PATCH 08/12] Remove references to BFO_0000002 --- src/ontology/obi-edit.owl | 10 +--------- 1 file changed, 1 insertion(+), 9 deletions(-) diff --git a/src/ontology/obi-edit.owl b/src/ontology/obi-edit.owl index a88f008a..bb933507 100644 --- a/src/ontology/obi-edit.owl +++ b/src/ontology/obi-edit.owl @@ -956,8 +956,6 @@ instance level relation [GOC:cjm] - - is_proxy_for position on a gel is_proxy_for mass and charge of molecule in an western blot. Florescent intensity is_proxy_for amount of protein labeled with GFP. Examples: A260/A280 (of a DNA sample) is_proxy_for DNA-purity. NMR Sample scan is a proxy for sample quality. @@ -1530,12 +1528,6 @@ https://sourceforge.net/tracker/index.php?func=detail&aid=3512902&group_ - - - - - - @@ -5863,7 +5855,7 @@ Proposal is to obsolete. - + ionize process From 2c3431292d0cfd24278af1ac5c3ae8c2861c443b Mon Sep 17 00:00:00 2001 From: Sebastian Duesing <66700705+sebastianduesing@users.noreply.github.com> Date: Thu, 19 Dec 2024 13:41:15 -0600 Subject: [PATCH 09/12] Remove references to BFO_0000003 --- src/ontology/obi-edit.owl | 8 -------- 1 file changed, 8 deletions(-) diff --git a/src/ontology/obi-edit.owl b/src/ontology/obi-edit.owl index bb933507..26f379e8 100644 --- a/src/ontology/obi-edit.owl +++ b/src/ontology/obi-edit.owl @@ -1299,8 +1299,6 @@ https://sourceforge.net/tracker/index.php?func=detail&aid=3512902&group_ - - process is result of The production of IFN-gamma by effector T cells is a process result of T cell stimulation through the TCR is a relationship between a process and a preceding occurrent that directly caused the later one to occur @@ -1528,12 +1526,6 @@ https://sourceforge.net/tracker/index.php?func=detail&aid=3512902&group_ - - - - - - From 66fa0bb83ca17dd0eea9e114f51b3dc1612a9224 Mon Sep 17 00:00:00 2001 From: Sebastian Duesing <66700705+sebastianduesing@users.noreply.github.com> Date: Thu, 19 Dec 2024 13:46:02 -0600 Subject: [PATCH 10/12] Remove references to BFO_0000004 --- src/ontology/obi-edit.owl | 8 -------- 1 file changed, 8 deletions(-) diff --git a/src/ontology/obi-edit.owl b/src/ontology/obi-edit.owl index 26f379e8..5ed19edb 100644 --- a/src/ontology/obi-edit.owl +++ b/src/ontology/obi-edit.owl @@ -1397,8 +1397,6 @@ https://sourceforge.net/tracker/index.php?func=detail&aid=3512902&group_ - - @@ -1526,12 +1524,6 @@ https://sourceforge.net/tracker/index.php?func=detail&aid=3512902&group_ - - - - - - From 75644d94d9d4b5d47c3e775b734da17776f4dd50 Mon Sep 17 00:00:00 2001 From: Sebastian Duesing <66700705+sebastianduesing@users.noreply.github.com> Date: Thu, 19 Dec 2024 13:58:03 -0600 Subject: [PATCH 11/12] Remove references to BFO_0000035 --- src/ontology/obi-edit.owl | 22 +++++----------------- 1 file changed, 5 insertions(+), 17 deletions(-) diff --git a/src/ontology/obi-edit.owl b/src/ontology/obi-edit.owl index 5ed19edb..e9e014af 100644 --- a/src/ontology/obi-edit.owl +++ b/src/ontology/obi-edit.owl @@ -1396,8 +1396,7 @@ https://sourceforge.net/tracker/index.php?func=detail&aid=3512902&group_ - - + @@ -1578,12 +1577,6 @@ https://sourceforge.net/tracker/index.php?func=detail&aid=3512902&group_ - - - - - - @@ -14256,15 +14249,10 @@ http://www.pdb.org/pdb/download/downloadFile.do?fileFormat=pdb&compression=N - - - - - - - - - + + + + From 6f6b23baeb4ac5189753a73b2fd8bf2c99dd938d Mon Sep 17 00:00:00 2001 From: Sebastian Duesing <66700705+sebastianduesing@users.noreply.github.com> Date: Thu, 19 Dec 2024 17:04:15 -0600 Subject: [PATCH 12/12] Update RO import and switch out 'bearer of' and 'inheres in' --- src/ontology/obi-edit.owl | 2 +- src/ontology/templates/administration.tsv | 10 +++++----- src/ontology/templates/assays.tsv | 12 ++++++------ src/ontology/templates/devices.tsv | 2 +- src/ontology/templates/epitope-assays.tsv | 2 +- src/ontology/templates/physical-examination.tsv | 2 +- 6 files changed, 15 insertions(+), 15 deletions(-) diff --git a/src/ontology/obi-edit.owl b/src/ontology/obi-edit.owl index e9e014af..3de56b23 100644 --- a/src/ontology/obi-edit.owl +++ b/src/ontology/obi-edit.owl @@ -59,7 +59,7 @@ - + en Ontology for Biomedical Investigations Advisors for this project come from the IFOMIS group, Saarbruecken and from the Co-ODE group in Manchester diff --git a/src/ontology/templates/administration.tsv b/src/ontology/templates/administration.tsv index c0f26942..39ad0dfb 100644 --- a/src/ontology/templates/administration.tsv +++ b/src/ontology/templates/administration.tsv @@ -1,14 +1,14 @@ ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type logical note parent class target of administration material administered administration technique objective associated axiom ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'realizes' some ('target of material addition role' and ('role of' some %)) SPLIT=| C 'realizes' some ('material to be added role' and ('role of' some %)) SPLIT=| C 'has part' some % SPLIT=| C achieves_planned_objective some % C % -OBI:0000281 intraperitoneal injection intraperitoneal injection is the injection of a material entity (bearing the administered substance role) into the peritoneum (bearing the target role) of an organism using a syringe BP equivalent intraperitoneal administration ('realizes' some ('function' and ('inheres in' some 'syringe'))) +OBI:0000281 intraperitoneal injection intraperitoneal injection is the injection of a material entity (bearing the administered substance role) into the peritoneum (bearing the target role) of an organism using a syringe BP equivalent intraperitoneal administration ('realizes' some ('function' and ('characteristic of' some 'syringe'))) OBI:0000429 intraperitoneal administration intraperitoneal administration The administration of a substance into the peritoneum of an organism Rats were injected intraperitoneally with either rrIL-6 (250 ng/0.5 ml) or equal-volume sterile saline twice within an interval of 24 h Person:Bjoern Peters equivalent administering substance in vivo peritoneum OBI:0000837 oral ingestion of pill oral ingestion of pill An adding a material entity to target with the entity is a pill and the target is the mouth Person:Alan Ruttenberg 2009/09/28 Alan Ruttenberg. Fucoidan-use-case equivalent oral administration pill ('has specified input' some 'pill') -OBI:0000934 intramuscular injection intramuscular injection is the injection of a material entity (bearing the administered substance role) into the muscle (bearing the target role) of an organism using a syringe equivalent administering substance in vivo skeletal muscle tissue ('realizes' some ('function' and ('inheres in' some 'syringe'))) -OBI:0000942 intradermal injection intradermal injection is the injection of a material entity (bearing the administered substance role) into the dermis (bearing the target role) of an organism using a syringe PERSON: Melanie Courtot equivalent administering substance in vivo dermis ('realizes' some ('function' and ('inheres in' some 'syringe'))) +OBI:0000934 intramuscular injection intramuscular injection is the injection of a material entity (bearing the administered substance role) into the muscle (bearing the target role) of an organism using a syringe equivalent administering substance in vivo skeletal muscle tissue ('realizes' some ('function' and ('characteristic of' some 'syringe'))) +OBI:0000942 intradermal injection intradermal injection is the injection of a material entity (bearing the administered substance role) into the dermis (bearing the target role) of an organism using a syringe PERSON: Melanie Courtot equivalent administering substance in vivo dermis ('realizes' some ('function' and ('characteristic of' some 'syringe'))) OBI:0000952 oral administration oral administration An administering substance in vivo into the mouth of an organism PERSON: Melanie Courtot equivalent administering substance in vivo mouth -OBI:0000954 subcutaneous injection subcutaneous injection is the injection of a material entity (bearing the administered substance role) into the hypodermis (bearing the target role) of an organism using a syringe PERSON: Melanie Courtot equivalent administering substance in vivo hypodermis ('realizes' some ('function' and ('inheres in' some 'syringe'))) +OBI:0000954 subcutaneous injection subcutaneous injection is the injection of a material entity (bearing the administered substance role) into the hypodermis (bearing the target role) of an organism using a syringe PERSON: Melanie Courtot equivalent administering substance in vivo hypodermis ('realizes' some ('function' and ('characteristic of' some 'syringe'))) OBI:0000983 intranasal mucosal administration intranasal mucosal administration The administration of a substance into the intranasal mucosis of an organism PERSON: Melanie Courtot equivalent administering substance in vivo mucosa of nasopharynx -OBI:0000994 intravenous injection intravenous injection is the injection of a material entity (bearing the administered substance role) into the vein (bearing the target role) of an organism using a syringe PERSON: Melanie Courtot equivalent administering substance in vivo vein ('realizes' some ('function' and ('inheres in' some 'syringe'))) +OBI:0000994 intravenous injection intravenous injection is the injection of a material entity (bearing the administered substance role) into the vein (bearing the target role) of an organism using a syringe PERSON: Melanie Courtot equivalent administering substance in vivo vein ('realizes' some ('function' and ('characteristic of' some 'syringe'))) OBI:0001174 passive immunization passive immunization adoptive transfer The injection of immune effector material (antibodies, T cells or B cells) into an organism so that the organisms immune system gains its immune effector function to recognize specific antigens. Giving VIG (concentrated antibodies from vaccinated donors) to a patient that is infected with smallpox. Transferring epitope specific T cells from one mouse into another. PERSON: Bjoern Peters, Randi Vita, Jason Greenbaum subclass administering substance in vivo adaptive immune receptor OBI:0003057 antibiotic administration process antibiotic administration process Administering substance in vivo where an antibiotic substance is administered to a living organism. Penn Group Chris Stoeckert|Cristian Cocos|Jie Zheng subclass administering substance in vivo antibacterial OBI:0003413 administering substance in vivo to cause disease An administration of substance in vivo with the intention to induce disease in the organism. IEDB IEDB subclass administering substance in vivo disease causation objective diff --git a/src/ontology/templates/assays.tsv b/src/ontology/templates/assays.tsv index 066cfd1e..7225c6bc 100644 --- a/src/ontology/templates/assays.tsv +++ b/src/ontology/templates/assays.tsv @@ -1,13 +1,13 @@ ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type logical note parent class material processing technique detection technique evaluant measurand analyte device reagent molecular label input output target entity target context objective associated axioms -ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some (% and 'has role' some 'evaluant role')) and (realizes some ('evaluant role' and ('role of' some %))) SPLIT=| C ('has specified input' some %) and (realizes some ('measurand role' and ('inheres in' some %))) C ('has specified input' some %) and (realizes some ('analyte role' and ('inheres in' some %))) C ('has specified input' some %) and (realizes some (function and ('inheres in' some %))) SPLIT=| C ('has specified input' some %) and (realizes some ('reagent role' and ('inheres in' some %))) C ('has specified input' some %) and (realizes some ('molecular label role' and ('inheres in' some %))) C 'has specified input' some % C 'has specified output' some % C 'has specified output' some ('is about' some %) C 'has specified output' some ('is about' some ( 'has assay target context' some %)) C achieves_planned_objective some % C % -CHMO:0000087 fluorescence microscopy assay fluorescence imaging|fluorescence microscopic imaging|FM Any type of light microscopy assay where the specimen can be made to fluoresce (emit energy as visible light) by illuminating it with light of specific wavelengths. These specimens are called fluorophores. CHMO subclass light microscopy assay ('material entity' and ('bearer of' some fluorescence)) +ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some (% and 'has role' some 'evaluant role')) and (realizes some ('evaluant role' and ('role of' some %))) SPLIT=| C ('has specified input' some %) and (realizes some ('measurand role' and ('characteristic of' some %))) C ('has specified input' some %) and (realizes some ('analyte role' and ('characteristic of' some %))) C ('has specified input' some %) and (realizes some (function and ('characteristic of' some %))) SPLIT=| C ('has specified input' some %) and (realizes some ('reagent role' and ('characteristic of' some %))) C ('has specified input' some %) and (realizes some ('molecular label role' and ('characteristic of' some %))) C 'has specified input' some % C 'has specified output' some % C 'has specified output' some ('is about' some %) C 'has specified output' some ('is about' some ( 'has assay target context' some %)) C achieves_planned_objective some % C % +CHMO:0000087 fluorescence microscopy assay fluorescence imaging|fluorescence microscopic imaging|FM Any type of light microscopy assay where the specimen can be made to fluoresce (emit energy as visible light) by illuminating it with light of specific wavelengths. These specimens are called fluorophores. CHMO subclass light microscopy assay ('material entity' and ('has characteristic' some fluorescence)) CHMO:0000089 confocal fluorescence microscopy assay CLSM|confocal fluorescence imaging|confocal laser scanning fluorescence microscopy|confocal laser scanning microscopy|confocal-laser scanning microscopy|fluorescence confocal microscopy|fluorescence confocal scanning laser microscopy|LSCM|scanning confocal fluorescence microscopy Microscopy where the specimen can be made to fluoresce (emit energy as visible light) by scanning a gas (Ar or Kr) laser spot of specific wavelength over its surface and using a spatial pinhole to eliminate out-of-focus fluorescence. CHMO subclass microscopy assay CHMO:0000102 light microscopy assay light microscopy|OM|optical microscopy Microscopy where the specimen is illuminated with visible light and a system of lenses is used to produce an image. CHMO subclass microscopy assay CHMO:0000701 liquid chromatography-tandem mass spectrometry LC-MSMS|LC-MS-MS|LC-MS/MS|liquid chromatography tandem mass spectroscopy|LC-MS2|liquid chromatography-tandem mass spectroscopy|LCMSMS|liquid chromatography tandem mass spectrometry|LC/MS/MS A method where a sample mixture is first separated by liquid chromatography before being ionised and characterised by mass-to-charge ratio and relative abundance using two mass spectrometers in series. CHMO subclass tandem mass spectrometry assay liquid chromatography OBI:0000117 Bernoulli trial pending final vetting An assay where the output data is a datum with one of two values denoting success and failure. OBI branch derived PlanAndPlannedProcess Branch subclass assay OBI:0000182 NMR 3D molecular structure determination assay A 3D molecular structure determination assay that uses magnetic properties of atomic nuclei to determine the 3D structure and dynamics of molecules in the input sample. IEDB Determining the binding of epitope-specific nanobody cAb-HuL5 to wild type human lysozyme by chemical shift perturbations in NMR spectra (Erwin De Genst, J Phys Chem B 2013). PlanAndPlannedProcess Branch|IEDB equivalent 3D molecular structure determination assay NMR instrument 3D structural organization datum OBI:0000185 imaging assay pending final vetting An assay that produces a picture of an entity. OBI branch derived PlanAndPlannedProcess Branch subclass assay image -OBI:0000201 radioactivity detection An assay that measures the amount of radiation in the radioactive spectrum (alpha, beta or gamma rays) emitted from an input material. IEDB Placing the evaluant input material close to a scintillation counter which emits light upon being hit with alpha/beta/gamma radiation and counting the frequency of light blasts to determine the radioactivity of the input material. PlanAndPlannedProcess Branch|IEDB equivalent assay ('material entity' and ('bearer of' some radioactive)) ('material entity' and ('bearer of' some radioactive)) +OBI:0000201 radioactivity detection An assay that measures the amount of radiation in the radioactive spectrum (alpha, beta or gamma rays) emitted from an input material. IEDB Placing the evaluant input material close to a scintillation counter which emits light upon being hit with alpha/beta/gamma radiation and counting the frequency of light blasts to determine the radioactivity of the input material. PlanAndPlannedProcess Branch|IEDB equivalent assay ('material entity' and ('has characteristic' some radioactive)) ('material entity' and ('has characteristic' some radioactive)) OBI:0000288 protein-protein interaction detection assay metadata incomplete An assay that determines interactions between proteins, such as protein-protein binding. subclass assay OBI:0000291 transcription factor binding site assay metadata complete TF binding An assay tthat determines DNA regions specifically recognized by proteins that function as transcription factors OBI Transcription factor binding site identification in yeast: a comparison of high-density oligonucleotide and PCR-based microarray platforms. Philippe Rocca-Serra https://sourceforge.net/p/obi/obi-terms/767/ subclass binding assay information content entity TF_binding_site OBI:0000366 metabolite profiling assay metadata complete metabolite assay|metabolomic assay An assay that detects and identifies chemical entities resulting from biochemical and cellular metabolism OBI Metabolite profiling of human colon carcinoma - deregulation of TCA cycle and amino acid turnover. Mol Cancer. 2008 Sep 18;7(1):72. PMID: 18799019 Philippe Rocca-Serra subclass assay specimen @@ -68,7 +68,7 @@ OBI:0000893 real time polymerase chain reaction assay metadata complete Q-PCR|q OBI:0000897 DEPC structure mapping assay ready for release A single-nucleotide-resolution nucleic acid structure mapping assay which determines nucleic acid secondary structure at a nucleotide resolution scale using DEPC as reagent and chemical probe RNA ontology PMID:2446263. Probing the structure of RNAs in solution. Nucleic Acids Res. 1987 Nov 25;15(22):9109-28. Philippe Rocca-Serra subclass single-nucleotide-resolution nucleic acid structure mapping assay using chemical probing ('deoxyribonucleic acid' or 'ribonucleic acid') measurement datum secondary structure of sequence macromolecule OBI:0000903 in vitro cell killing assay A cell killing assay that measures if and how many target cells are actively killed by other cells in a cell culture. IEDB Autologous EBV-transformed B-LCL were used as target cells for the influenza virus-specific CTL assays. Equal volumes of target and effector cells were added to tissue culture plates, and 1:2 serial dilutions of effectors were made. After a 4-h incubation of the effector cells with the target cells, supernatants were collected and counted with the LKB 1272 Clinigamma counter. Percent specific killing was determined with the following equation: (experimental 51Cr release - spontaneous 51Cr release)/(maximum 51Cr release - spontaneous 51Cr release) x 100. IEDB equivalent cell-cell killing assay cultured cell population OBI:0000904 reporter cell line analyte detection bioassay An analyte assay in which a cell line whose growth is known to be affected by the presence of a specific type of material (the anlyte) is cultured in the presence of an input material (the evaluant) in order to detect presence of the analyte in the evaluant. IEDB CTLL-2 cells were grown in the presence of hybridoma supernatants and their growth was monitored by a 3H-thymidine incorporation cell proliferation assay in order to detect IL-2 in the hybridoma supernatant. IEDB subclass logical definition does not specify how the cell line is used as a reporter analyte assay maintaining cell culture cell line -OBI:0000910 radio immuno assay An assay in which a radioactive labeled antigen or antibody is used to determine the interaction between an antigen and its receptor. This can be used to detect the presence of an antigen of interest in an input sample or determine the specificity of an input antibody. IEDB To evaluate the specificity of antibody binding to 35S-labeled IA-2(256-760) in comparison with 35S-labeled IA-2IC construct, the mutual inhibition activity of different concentrations of unlabeled IA-2IC and/or IA-2(256-760) fragments were tested. Unlabeled recombinant IA-2(256-760) and/or IA-2IC (0.5-, 1-, 2-, and 4-fold the amount of 35S-labeled protein) were added to each tube and incubated overnight at 4C with patient sera. The following day, after incubation with radiolabeled 35 IA-2(256-760) or 35S IA-2IC proteins, samples were processed with the usual radioimmunoprecipitation assay. IEDB subclass logical definition does not capture the interaction aspect assay ('material entity' and ('bearer of' some radioactive)) +OBI:0000910 radio immuno assay An assay in which a radioactive labeled antigen or antibody is used to determine the interaction between an antigen and its receptor. This can be used to detect the presence of an antigen of interest in an input sample or determine the specificity of an input antibody. IEDB To evaluate the specificity of antibody binding to 35S-labeled IA-2(256-760) in comparison with 35S-labeled IA-2IC construct, the mutual inhibition activity of different concentrations of unlabeled IA-2IC and/or IA-2(256-760) fragments were tested. Unlabeled recombinant IA-2(256-760) and/or IA-2IC (0.5-, 1-, 2-, and 4-fold the amount of 35S-labeled protein) were added to each tube and incubated overnight at 4C with patient sera. The following day, after incubation with radiolabeled 35 IA-2(256-760) or 35S IA-2IC proteins, samples were processed with the usual radioimmunoprecipitation assay. IEDB subclass logical definition does not capture the interaction aspect assay ('material entity' and ('has characteristic' some radioactive)) OBI:0000911 real time reverse-transcription polymerase chain reaction assay metadata complete RRT-PCR|qRT-PCR|RT-rt PCR An assay that uses a reverse transcription step (an RNA strand is reverse transcribed into its DNA complement using the enzyme reverse transcriptase) before a PCR assay. Melanie Courtot|Bjoern Peters subclass assay artificially induced reverse transcription real time polymerase chain reaction assay information content entity gene expression OBI:0000912 X-ray crystallography 3D molecular structure determination assay A 3D molecular structure determination assay in which the diffraction of pattern of X-ray beams in a crystal of purified material entities is used to resolve the 3-dimensional structure of the material entity of interest. IEDB Crystallizing an antibody:antigen complex, and recording the diffraction pattern of a synchrotron beam, and assembling the 3d complex structure based on homologous complexes. IEDB subclass logical definition does not capture diffraction pattern 3D molecular structure determination assay X-ray source OBI:0000913 promoter activity detection by reporter gene assay An assay in which the activity of a promoter in a cell is monitored by using a reporter gene that was inserted in a genomic location under control of the promoter and whose expression can be easily detected based on qualities or functions of the gene. IEDB A T cell hybridoma in which the beta-galactosidase gene (lacZ) was inserted under the control of the IL-2 promoter, is detected by adding the X-gal substrate which when cleaved by lacZ results in detectable blue color. IEDB subclass logical definition does not capture gene insertion assay cell core promoter sequence-specific DNA binding @@ -141,7 +141,7 @@ OBI:0001476 phage display binding assay A binding assay in which a collection OBI:0001488 epitope tolerance induction experiment metadata complete tolerance induction An efficacy of epitope intervention experiment that tests the ability of the intervention to decrease an existing immune response IEDB IEDB subclass efficacy of epitope intervention experiment OBI:0001491 binding assay using radioactivity detection metadata complete A binding assay that uses radioactivity detection as an indicator of binding. IEDB Bjoern Peters|Randi Vita equivalent binding assay radioactivity detection OBI:0001499 binding assay using fluorescence detection metadata complete A binding assay that uses fluorescence detection as an indicator of binding. IEDB Bjoern Peters|Randi Vita equivalent binding assay fluorescence detection assay -OBI:0001501 fluorescence detection assay An assay in which a material's fluorescence is determined. IEDB Using a laser to stimulate a cell culture that was previously labeled with fluorescent antibodies to detect light emmission at a different wavelength in order to determine the presence of surface markers the antibodies are specific for. IEDB equivalent assay ('material entity' and ('bearer of' some fluorescence)) +OBI:0001501 fluorescence detection assay An assay in which a material's fluorescence is determined. IEDB Using a laser to stimulate a cell culture that was previously labeled with fluorescent antibodies to detect light emmission at a different wavelength in order to determine the presence of surface markers the antibodies are specific for. IEDB equivalent assay ('material entity' and ('has characteristic' some fluorescence)) OBI:0001591 direct binding assay metadata complete A binding assay that measures the formation or disassociation of a complex of 2 material entities directly without use of a competitve ligand. IEDB Detecting the binding of a fluorescently labeled antibody to a peptide bound to the bottom of an ELISA plate, by incubating the antibody in the well, washing the plate, and detecing fluorescence which is a proxy for the presence of the bound antibody._ Bjoern Peters|Randi Vita subclass binding assay OBI:0001593 competitive inhibition of binding assay A binding assay that detects the inhibition of binding between 2 material entities known to form a complex by the addition of a third material entity of interest. Inhibition of binding between the 2 materials reflects binding by the third material. IEDB Detecting the inhibition of binding of a fluorescently labeled antibody to its known protein ligand bound to the bottom of an ELISA plate, by incubating the antibody in the presence of a peptide of interest, adding it to the plate, washing the plate, and detecing fluorescence which is a proxy for the presence of the bound antibody. Reduction in binding due to the presence of the peptide indicates that the antibody binds the peptide._ IEDB subclass logical definition does not capture inhibition of binding binding assay ('material entity' and ('has role' some 'competitive binding reference ligand role')) OBI:0001624 organism species detection assay metadata complete organism identification assay An organism detection assay that identifies the organism species in a specimen. NIAID GSCID-BRC metadata working group Chris Stoeckert|Jie Zheng equivalent organism detection assay (achieves_planned_objective some 'organism species detection objective') @@ -662,7 +662,7 @@ OBI:0003661 in vitro CRISPR screen using flow cytometry in vitro CRISPR perturba OBI:0003662 single-nucleus methylcytosine and transcriptome sequencing assay single-nucleus methylcytosine and transcriptome sequencing assay snmCT-seq A DNA methylation profiling by high throughput sequencing assay that measures the cytosine DNA methylation and gene expression signature of single nuclei. Jennifer Jou https://www.biorxiv.org/content/10.1101/434845v1 Sebastian Duesing|Jennifer Jou Jennifer Jou https://github.com/obi-ontology/obi/issues/1785 equivalent DNA methylation profiling by high throughput sequencing assay artificially induced reverse transcription RNA extract DNA sequencer RNA extract sequence data primary structure of RNA molecule OBI:0003686 chromatin accessibility assay chromatin accessibility assay An assay that determines which regions of a DNA molecule are in the form of euchromatin and thus able to make direct physical contact with (i.e. are accessible to) other molecules such as RNA polymerase, transcription factors, etc. Michelle Giglio Sebastian Duesing|Michelle Giglio|Bjoern Peters Jennifer Jou https://github.com/obi-ontology/obi/issues/1813 subclass assay OBI:0003687 m6A-MTase sequencing assay m6A-MTase sequencing assay Fiber-seq A DNA methylation profiling assay in which chromatin stencils are created by treating nuclei with m6A methyltransferase (MTase) and then sequenced using single-molecule circular consensus sequencing to identify regions of accessible DNA at nucleotide resolution. Jennifer Jou https://pubmed.ncbi.nlm.nih.gov/32587015/ Jennifer Jou|Sebastian Duesing Jennifer Jou https://github.com/obi-ontology/obi/issues/1813 subclass chromatin accessibility assay -OBI:0302736 comet assay ready for release single cell gel electrophoresis assay|SCGE assay An assay that measures DNA damage (DNA breakage) in eucaryotic cells exposed to a challenge by determining the size and shape of DNA migration by detecting fluorescently labeled DNA from a cell placed in an electric field using gel electrophoresis PMID:7686265 PMID: 18326531.Mutagenesis. 2008 Mar 6.Recommendations for design of the rat comet assay. Philippe Rocca-Serra subclass assay fluorescence microscopy assay cell ('material entity' and ('has role' some 'dye role') and ('bearer of' some fluorescence)) agarose gel information content entity DNA damage response +OBI:0302736 comet assay ready for release single cell gel electrophoresis assay|SCGE assay An assay that measures DNA damage (DNA breakage) in eucaryotic cells exposed to a challenge by determining the size and shape of DNA migration by detecting fluorescently labeled DNA from a cell placed in an electric field using gel electrophoresis PMID:7686265 PMID: 18326531.Mutagenesis. 2008 Mar 6.Recommendations for design of the rat comet assay. Philippe Rocca-Serra subclass assay fluorescence microscopy assay cell ('material entity' and ('has role' some 'dye role') and ('has characteristic' some fluorescence)) agarose gel information content entity DNA damage response OBI:0302737 PCR-SSCP assay ready for release polymerase chain reaction-single strand conformation polymorphism assay An assay that identifies DNA sequence variation (mutation, deletion, insertions) in target DNA sequences amplified using polymerase chain reaction using gel electrophoresis and denaturating conditions PMID:18219595 PMID: 17334176.Hum Exp Toxicol. 2007 Jan;26(1):9-18.Is there a role for PCR-SSCP among the methods for missense mutation detection of TP53 gene? Philippe Rocca-Serra subclass genotyping assay polymerase chain reaction|material component separation amplified DNA (image and 'genotype information') OBI:0600002 tumor grading pending final vetting grading of tumor An assay that determines the grade (severity/stage) of a tumor sample, used in cancer biology to describe abnormalities/qualities of tumor cells or tissues. Values can be described by terms from NCI Thesaurus. OBI branch derived; submitted by MO Compiled by Helen Parkinson for Transcriptomics thanks to Adam Witney subclass assay specimen disease course OBI:0600017 assay detecting a molecular label pending final vetting An assay that detects the presence or a quality of a molecular label which is a proxy for the detection of the molecular target to which the label is attached OBI developer call, 3-12-12 Determination of the amount of phycoerytherin label present in a cell population stained with anti-CD8-PE in order to determine the percentage of CD8+ T cells present Matthew Brush subclass assay molecular-labeled material measurement datum molecular-labeled material diff --git a/src/ontology/templates/devices.tsv b/src/ontology/templates/devices.tsv index 32bce389..aa2112ac 100644 --- a/src/ontology/templates/devices.tsv +++ b/src/ontology/templates/devices.tsv @@ -309,7 +309,7 @@ OBI:0001204 SNP microarray SNP microarray metadata complete A DNA microarray us OBI:0001307 tiling microarray tiling microarray metadata complete genome tiling array A DNA microarray which has short fragments of nucleic acid immobilized on a substrate. These are designed to cover the whole genome of the target species. Tiling arrays are used to determine genome binding in ChIP assays or to identify transcribed regions. EFO_0002704: tiling array Person: Helen Parkinson DNA microarray OBI:0001865 assay array metadata complete A device made to be used in an analyte assay for immobilization of substances that bind the analyte at regular spatial positions on a surface. Penn Group PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg device solid support function OBI:0001869 Illumina BeadChip metadata complete An array that consists of 3-micron silica beads that self assemble in microwells on either of two materials: fiber optic bundles or planar silica slides. http://www.illumina.com/technology/beadarray_technology.ilmn PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg, Venkat Malladi assay array Illumina -OBI:0001870 Illumina methylation BeadChip metadata complete A BeadChip made for an analyte assay that generates information about DNA methylation. Penn Group PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg Illumina BeadChip ('bearer of' some (function and ('realized in' only (assay and ('has specified output' some ('measurement datum' and ('is about' some (deoxyribonucleotide and ('has part' some 'methyl group'))))))))) +OBI:0001870 Illumina methylation BeadChip metadata complete A BeadChip made for an analyte assay that generates information about DNA methylation. Penn Group PERSON: Chris Stoeckert, Jie Zheng, Alan Ruttenberg Illumina BeadChip ('has characteristic' some (function and ('realized in' only (assay and ('has specified output' some ('measurement datum' and ('is about' some (deoxyribonucleotide and ('has part' some 'methyl group'))))))))) OBI:0001871 LSRFortessa X-20 metadata complete A flow cytometer analyzer manifactured by Becton ans Dickinson. Can be configured with up to 5 lasers, 488nm, 532 or 561 nm, 640 nm, 405 nm, 355 nm for measuring up to 20 parameters simultaneously. http://www.bdbiosciences.com/instruments/lsrx20/index.jsp?WT.srch=1&gclid=CJjJ8JTR5LoCFXBo7AodZycAbg Anna Maria Masci flow cytometer analyzer Becton Dickinson (BD Biosciences) OBI:0001971 Ion 316 Chip v2 Ion 316 Chip v2 Ion PGM 316 Chip|Ion 316 Chip|Ion PGM 316 Chip v2 An ion semiconductor chip manufactured by Life Technologies which detects polymerase-driven base incorporation to translate into digital form. The 316 chip is compatible with the Ion Torrent PGM and has a run time of: 3.0 hours for 200 bp reads with an output of 30-50 Mb, 4.9 hours for 400 bp reads with an output of 60 Mb-1 Gb. http://www.lifetechnologies.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-run-sequence/ion-pgm-ion-proton-system-chips.html PERSON: Sagar Jain Issue Tracker #774 https://sourceforge.net/p/obi/obi-terms/774/ ion semiconductor chip OBI:0001972 Ion 318 Chip v2 Ion 318 Chip v2 Ion 318 Chip|Ion PGM 318 Chip|Ion PGM 318 Chip v2 An ion semiconductor chip manufactured by Life Technologies which detects polymerase-driven base incorporation to translate into digital form. The 318 chip is compatible with the Ion Torrent PGM and has a run time of: 4.4 hours for 200 bp reads with an output of 60 Mb-1 Gb, 7.3 hours for 400 bp reads with an output of 1.2 Gb-2 Gb. http://www.lifetechnologies.com/us/en/home/life-science/sequencing/next-generation-sequencing/ion-torrent-next-generation-sequencing-workflow/ion-torrent-next-generation-sequencing-run-sequence/ion-pgm-ion-proton-system-chips.html PERSON: Sagar Jain Issue Tracker #775 https://sourceforge.net/p/obi/obi-terms/775/ ion semiconductor chip diff --git a/src/ontology/templates/epitope-assays.tsv b/src/ontology/templates/epitope-assays.tsv index d1e7e6d6..da3ee3b5 100644 --- a/src/ontology/templates/epitope-assays.tsv +++ b/src/ontology/templates/epitope-assays.tsv @@ -1,5 +1,5 @@ Ontology ID label editor preferred term has curation status alternative label IEDB alternative term definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type parent class material processing technique detection technique reagent input output MHC source target entity target context unit -ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| A IEDB alternative term AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some %) and (realizes some ('reagent role' and ('inheres in' some %))) C 'has specified input' some % C 'has specified output' some % C 'has specified input' some (% and ('has part' some 'MHC protein complex')) C 'has specified output' some ('is about' some %) C 'has specified output' some ('is about' some ( 'has assay target context' some %)) C 'has specified output' some ('has measurement unit label' value %) +ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| A IEDB alternative term AL definition@en A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some % SPLIT=| C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some %) and (realizes some ('reagent role' and ('characteristic of' some %))) C 'has specified input' some % C 'has specified output' some % C 'has specified input' some (% and ('has part' some 'MHC protein complex')) C 'has specified output' some ('is about' some %) C 'has specified output' some ('is about' some ( 'has assay target context' some %)) C 'has specified output' some ('has measurement unit label' value %) OBI:0001194 ELISPOT assay measuring epitope specific transforming growth factor-beta production by T cells TGFb release|ELISPOT An enzyme-linked immunospot assay that detects transforming growth factor-beta production by T cells. IEDB PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters equivalent enzyme-linked immunospot assay ('transforming growth factor beta production' and ('process is result of' some 'MHC:epitope complex binding to TCR')) OBI:0001196 cytometric bead array assay measuring epitope specific IP-10 production by T cells CXCL10/IP-10 release|cytometric bead array A cytometric bead array assay that detects IP-10 production by T cells. IEDB PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters equivalent antigen detection by cytometric bead array assay ('IP-10 production' and ('process is result of' some 'MHC:epitope complex binding to TCR')) OBI:0001198 assay measuring epitope specific interleukin-27 production by T cells IL-27 release|biological activity A T cell epitope specific cytokine production assay that detects interleukin-27 production by T cells. IEDB PERSON:Randi Vita, Jason Greenbaum, Bjoern Peters equivalent assay ('interleukin-27 production' and ('process is result of' some 'MHC:epitope complex binding to TCR')) diff --git a/src/ontology/templates/physical-examination.tsv b/src/ontology/templates/physical-examination.tsv index ede2326d..d6380b55 100644 --- a/src/ontology/templates/physical-examination.tsv +++ b/src/ontology/templates/physical-examination.tsv @@ -1,5 +1,5 @@ ontology ID label editor preferred term has curation status alternative label definition definition source example of usage term editor editor note curator note ontology term requester term tracker item logical type logical note parent class detection technique evaluant device input output anatomical site assessed biological trait -ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some (% and 'has role' some 'evaluant role')) and (realizes some ('evaluant role' and ('role of' some %))) SPLIT=| C ('has specified input' some %) and (realizes some (function and ('inheres in' some %))) SPLIT=| C 'has specified input' some % C 'has specified output' some % C 'has specified output' some ('is about' some %) C 'has specified output' some ('is quality measurement of' some %) +ID A rdfs:label A editor preferred term AI has curation status A alternative label SPLIT=| AL definition@en SPLIT=| A definition source SPLIT=| A example of usage SPLIT=| A term editor SPLIT=| A editor note SPLIT=| A curator note SPLIT=| A ontology term requester A term tracker item CLASS_TYPE C % C 'has part' some ( % and 'detection technique') SPLIT=| C ('has specified input' some (% and 'has role' some 'evaluant role')) and (realizes some ('evaluant role' and ('role of' some %))) SPLIT=| C ('has specified input' some %) and (realizes some (function and ('characteristic of' some %))) SPLIT=| C 'has specified input' some % C 'has specified output' some % C 'has specified output' some ('is about' some %) C 'has specified output' some ('is quality measurement of' some %) OBI:0003501 functional assessment of individual A physical examination of an organism's ability to perform functional activities. Critical Path Institute Daniel Olson, ORCID: 0000-0002-8134-1207 https://github.com/obi-ontology/obi/issues/1637 subclass physical examination of an organism OBI:0003502 facial atrophy assessment An observational assessment of the loss of facial muscle tissue due to inactivity or disease. Critical Path Institute Daniel Olson, ORCID: 0000-0002-8134-1207 https://github.com/obi-ontology/obi/issues/1637 subclass observational assessment of individual facial muscle facial muscle performance OBI:0003503 tongue atrophy assessment An observational assessment of the loss of muscle tissue related to tongue movement due to inactivity or disease. Critical Path Institute Daniel Olson, ORCID: 0000-0002-8134-1207 https://github.com/obi-ontology/obi/issues/1637 subclass observational assessment of individual tongue facial muscle performance